Pipramadol

Pipramadol
Clinical data
Other names	FQ 27-096
Identifiers
	IUPAC name 2-[1-[2-(2-chlorophenyl)ethyl]-4-hydroxypiperidin-4-yl]-N-cyclohexyl-N-methylpropanamide;
ChemSpider	2310156;
CompTox Dashboard (EPA)	DTXSID40866480 ;
Chemical and physical data
Formula	C23H35ClN2O2
Molar mass	407.00 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C(=O)N(C)C1CCCCC1)C2(CCN(CC2)CCC3=CC=CC=C3Cl)O;
	InChI InChI=1S/C23H35ClN2O2/c1-18(22(27)25(2)20-9-4-3-5-10-20)23(28)13-16-26(17-14-23)15-12-19-8-6-7-11-21(19)24/h6-8,11,18,20,28H,3-5,9-10,12-17H2,1-2H3; Key:JRLWHJKUNYBJRC-UHFFFAOYSA-N;

Pipramadol is an opioid narcotic with potent analgesic properties.^[1]

Review:^[2]

References

^ Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry 26 (1): 42–50. doi:10.1021/jm00355a010.
^ Kurbat, N. M.; Praliev, K. D.; Salita, T. A.; Yu, V. K.; Verina, E. L. (1991). "Neuropharmacological activity of piperidine derivatives (a review)". Pharmaceutical Chemistry Journal. 25 (7): 450–462. doi:10.1007/BF00771998.