Zidebactam

Zidebactam
Legal status
Legal status	Investigational;
Identifiers
	IUPAC name [(2S,5R)-7-oxo-2-[[[(3R)-piperidine-3-carbonyl]amino]carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate;
CAS Number	1436861-97-0;
PubChem CID	77846445;
DrugBank	DB13090;
ChemSpider	44209501;
UNII	YPM97423DB;
ChEMBL	ChEMBL4533605;
Chemical and physical data
Formula	C13H21N5O7S
Molar mass	391.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1C[C@H](CNC1)C(=O)NNC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OS(=O)(=O)O;
	InChI InChI=1S/C13H21N5O7S/c19-11(8-2-1-5-14-6-8)15-16-12(20)10-4-3-9-7-17(10)13(21)18(9)25-26(22,23)24/h8-10,14H,1-7H2,(H,15,19)(H,16,20)(H,22,23,24)/t8-,9-,10+/m1/s1; Key:YCZPXRQPDCXTIO-BBBLOLIVSA-N;

Zidebactam (WCK-5107) is an antibiotic adjuvant drug which acts as a beta-lactamase inhibitor, preventing the breakdown of other antibiotic drugs.^[1]

References

^ Karvouniaris M, Almyroudi MP, Abdul-Aziz MH, Blot S, Paramythiotou E, Tsigou E, et al. (April 2023). "Novel Antimicrobial Agents for Gram-Negative Pathogens". Antibiotics. 12 (4). Basel, Switzerland: 761. doi:10.3390/antibiotics12040761. PMC 10135111. PMID 37107124.