Wikipedia:Version 1.0 Editorial Team/U.S. Highway system articles by quality log
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December 29, 2024
[edit]Renamed
[edit]- Anniston Eastern Bypass renamed to U.S. Route 431 in Alabama.
- Arrowhead Trafficway renamed to U.S. Route 169 in Missouri.
- BIA Road 18 renamed to Indian Reservation Roads Program.
- BIA Route 125 renamed to Indian Reservation Roads Program.
- BIA Route 14 renamed to Indian Reservation Roads Program.
- BIA Route 15 renamed to Indian Reservation Roads Program.
- BIA Route 221 renamed to Indian Reservation Roads Program.
- BIA Route 41 renamed to Indian Reservation Roads Program.
- BIA Route 6 renamed to Indian Reservation Roads Program.
- BIA Route 60 renamed to Indian Reservation Roads Program.
- BIA Route 62 renamed to Indian Reservation Roads Program.
- BIA Route 6660 renamed to Indian Reservation Roads Program.
- BIA Route 6710 renamed to Indian Reservation Roads Program.
- BIA Route 68 renamed to Indian Reservation Roads Program.
- BIA Route N12 renamed to Indian Reservation Roads Program.
- Bannered routes of U.S. Route 270 renamed to U.S. Route 270.
- Business routes of U.S. Route 24 in Michigan renamed to U.S. Route 24 in Michigan.
- City Avenue renamed to U.S. Route 1 in Pennsylvania.
- Col. 'Doc' Clyde Stinson Perimeter renamed to U.S. Route 441.
- Columbia Parkway renamed to U.S. Route 50 in Ohio.
- Connector routes of U.S. Route 24 in Michigan renamed to List of state trunkline highways in Michigan.
- Danville Expressway renamed to U.S. Route 29 in Virginia.
- Falls-to-Falls Corridor renamed to U.S. Route 53.
- Federal Lands Highway Program renamed to Federal Highway Administration.
- Florida State Road 95 renamed to U.S. Route 29 in Florida.
- Hoosier Heartland Industrial Corridor renamed to U.S. Route 24.
- I-35W/US 10/I-694 North Central Corridor Reconstruction Project renamed to Interstate 694.
- James V. Hansen Highway renamed to U.S. Route 89 in Utah.
- Johnson County Line-Ozark-Crawford County Line Road, Altus Segment renamed to U.S. Route 64 in Arkansas.
- Kings Hill Scenic Byway renamed to U.S. Route 89 in Montana.
- List of Interstate and U.S. Highways in Washington renamed to List of Interstate Highways in Washington.
- List of intrastate U.S. Highways renamed to List of United States Numbered Highways.
- Maryland Route 826 renamed to List of state highways in Maryland shorter than one mile (800–899).
- Maryland Route 831 renamed to List of state highways in Maryland shorter than one mile (800–899).
- Midland Trail (West Virginia) renamed to U.S. Route 60 in West Virginia.
- Old U.S. Route 64 (Menifee, Arkansas) renamed to U.S. Route 64 in Arkansas.
- Old U.S. Route 64 (Scotia, Arkansas) renamed to U.S. Route 64 in Arkansas.
- Old U.S. Route 64 (Van Buren, Arkansas) renamed to U.S. Route 64 in Arkansas.
- Old U.S. Route 71 (Ogden, Arkansas) renamed to U.S. Route 71 in Arkansas.
- Royal Gorge Boulevard renamed to U.S. Route 50 in Colorado.
- Sixth Street Expressway renamed to U.S. Route 50 in Ohio.
- Skokie Highway renamed to U.S. Route 41 in Illinois.
- Special routes of U.S. Route 160 renamed to U.S. Route 160.
- Special routes of U.S. Route 218 renamed to U.S. Route 218.
- Special routes of U.S. Route 3 renamed to U.S. Route 3.
- Special routes of U.S. Route 99 renamed to U.S. Route 99.
- U.S. Highway 1 Business (St. Augustine, Florida) renamed to Special routes of U.S. Route 1.
- U.S. Highway 62 Business renamed to Special routes of U.S. Route 62.
- U.S. Highway 62 Business (Cotter) renamed to Special routes of U.S. Route 62.
- U.S. Route 1/9 Business renamed to New Jersey Route 139.
- U.S. Route 101E (California) renamed to Interstate 880 (California).
- U.S. Route 101W (California) renamed to Van Ness Avenue.
- U.S. Route 101 Alternate (Ilwaco, Washington) renamed to U.S. Route 101 in Washington.
- U.S. Route 101 Alternate (Long Beach, California) renamed to California State Route 1.
- U.S. Route 101 Alternate (Los Angeles, California) renamed to California State Route 1.
- U.S. Route 101 Alternate (Santa Monica, California) renamed to California State Route 1.
- U.S. Route 101 Business (Astoria, Oregon) renamed to Special routes of U.S. Route 101.
- U.S. Route 101 Business (Fortuna, California) renamed to Special routes of U.S. Route 101.
- U.S. Route 101 Business (McKinleyville, California) renamed to Special routes of U.S. Route 101.
- U.S. Route 101 Business (Rio Dell, California) renamed to California State Route 283.
- U.S. Route 101 Business (Ventura, California) renamed to Special routes of U.S. Route 101.
- U.S. Route 101 Bypass (Los Angeles, California) renamed to Santa Ana Freeway.
- U.S. Route 101 Bypass (San Francisco, California) renamed to Bayshore Freeway.
- U.S. Route 101 Truck (Port Angeles, Washington) renamed to Washington State Route 117.
- U.S. Route 102 renamed to U.S. Route 141.
- U.S. Route 104 renamed to New York State Route 104.
- U.S. Route 106 renamed to Pennsylvania Route 106.
- U.S. Route 109 renamed to U.S. Route 9 in New York.
- U.S. Route 10N (Minnesota) renamed to U.S. Route 10 in Minnesota.
- U.S. Route 10N (Montana) renamed to List of U.S. Highways in Montana.
- U.S. Route 10S (Minnesota) renamed to U.S. Route 10 in Minnesota.
- U.S. Route 10S (Montana) renamed to List of U.S. Highways in Montana.
- U.S. Route 10 Alternate (Drummond–Anaconda, Montana) renamed to Montana Highway 1.
- U.S. Route 10 Alternate (Seattle, Washington) renamed to Washington State Route 900.
- U.S. Route 10 Alternate (Washington) renamed to U.S. Route 10 Alternate.
- U.S. Route 10 Business (Clare, Michigan) renamed to Business routes of U.S. Route 10 in Michigan.
- U.S. Route 10 Business (Flint, Michigan) renamed to Business routes of U.S. Route 10 in Michigan.
- U.S. Route 10 Business (Midland, Michigan) renamed to Business routes of U.S. Route 10 in Michigan.
- U.S. Route 10 Business (Neillsville, Wisconsin) renamed to U.S. Route 10 in Wisconsin.
- U.S. Route 10 Business (Pontiac, Michigan) renamed to Business routes of U.S. Route 10 in Michigan.
- U.S. Route 10 Business (Reed City, Michigan) renamed to Business routes of U.S. Route 10 in Michigan.
- U.S. Route 110 in Wisconsin renamed to Wisconsin Highway 110.
- U.S. Route 111 Alternate (York, Pennsylvania) renamed to U.S. Route 111.
- U.S. Route 112 renamed to U.S. Route 12 in Michigan.
- U.S. Route 112S renamed to U.S. Route 12 in Michigan.
- U.S. Route 112 (1925) renamed to Wisconsin Highway 110.
- U.S. Route 112 (Wisconsin) renamed to Wisconsin Highway 110.
- U.S. Route 112 Business (Niles, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 112 Business (Ypsilanti, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 112 Bypass (Ypsilanti, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 113 Alternate (Delaware) renamed to U.S. Route 113.
- U.S. Route 113 Business (Snow Hill, Maryland) renamed to U.S. Route 113.
- U.S. Route 116 renamed to U.S. Route 14.
- U.S. Route 117 (1926) renamed to U.S. Route 158.
- U.S. Route 117 (1927–1932) renamed to U.S. Route 158.
- U.S. Route 117 (North Carolina–Virginia) renamed to U.S. Route 158.
- U.S. Route 117 Alternate (Burgaw, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Alternate (Calypso–Brogden, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Alternate (Goldsboro, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Alternate (Goldsboro–Wilson, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Business (Burgaw, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Business (Calypso–Mount Olive, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Business (Goldsboro, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Connector (Calypso, North Carolina) renamed to U.S. Route 117.
- U.S. Route 117 Connector (North Carolina) renamed to U.S. Route 117.
- U.S. Route 118 renamed to U.S. Route 151.
- U.S. Route 11E Business (Greeneville, Tennessee) renamed to U.S. Route 11E.
- U.S. Route 11 Alternate (Chattanooga, Tennessee) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Alternate (Lemoyne, Pennsylvania) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Alternate (Salem–Roanoke, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Alternate (Winchester, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Business (Athens, Tennessee) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Business (Chattanooga, Tennessee) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Business (Lexington, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Business (Meridian, Mississippi) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Business (Staunton, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Bypass (Chattanooga, Tennessee) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Bypass (Cleveland, Tennessee) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Bypass (Lemoyne, Pennsylvania) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Bypass (Lexington, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Bypass (Tuscaloosa, Alabama) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Truck (Birmingham, Alabama) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Truck (Bristol, Virginia) renamed to Special routes of U.S. Route 11.
- U.S. Route 11 Truck (Staunton, Virginia) renamed to Virginia State Route 261.
- U.S. Route 120 renamed to Pennsylvania Route 120.
- U.S. Route 120 (Wyoming) renamed to U.S. Route 26.
- U.S. Route 121 (1926) renamed to U.S. Route 52.
- U.S. Route 121 (North Carolina–Virginia) renamed to U.S. Route 52.
- U.S. Route 121 (Virginia-North Carolina) renamed to U.S. Route 52.
- U.S. Route 122 (1926–1934) renamed to U.S. Route 202.
- U.S. Route 122 (Delaware–New Jersey) renamed to U.S. Route 202.
- U.S. Route 122 in New York renamed to U.S. Route 202 in New York.
- U.S. Route 122 in Pennsylvania renamed to U.S. Route 122.
- U.S. Route 123 (1930s) renamed to U.S. Route 119.
- U.S. Route 123 (Kentucky) renamed to U.S. Route 119.
- U.S. Route 123 Alternate (Greenville, South Carolina) renamed to U.S. Route 123.
- U.S. Route 123 Business (Easley, South Carolina) renamed to U.S. Route 123.
- U.S. Route 123 Business (Seneca, South Carolina) renamed to U.S. Route 123.
- U.S. Route 123 Connector (Easley, South Carolina) renamed to U.S. Route 123.
- U.S. Route 124 renamed to Illinois Route 116.
- U.S. Route 126 renamed to Oregon Route 126.
- U.S. Route 127 Business (Albany, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 127 Business (Alma, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Clare, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Harrison, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Ithaca, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Jackson, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Jamestown, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 127 Business (Lansing, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Lawrenceburg, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 127 Business (Mason, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Mount Pleasant, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (Mt. Pleasant, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (St. Johns, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Business (St. Louis, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 127 Bypass (Danville, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 127 Bypass (Harrodsburg, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 127 Bypass (Lawrenceburg, Kentucky) renamed to Special routes of U.S. Route 127 in Kentucky.
- U.S. Route 129 Alternate (Hawkinsville–Macon, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Alternate (Jefferson, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Alternate (Old Town, Florida) renamed to U.S. Route 129 in Florida.
- U.S. Route 129 Business (Arcade–Jefferson, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Business (Eatonton, Georgia) renamed to Georgia State Route 24.
- U.S. Route 129 Business (Gainesville, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Business (Hawkinsville, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Business (Watkinsville, Georgia) renamed to Georgia State Route 24.
- U.S. Route 129 Bypass (Cleveland, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Bypass (Gainesville, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Bypass (Madison, Georgia) renamed to Georgia State Route 24.
- U.S. Route 129 Temporary (Branford–Live Oak, Florida) renamed to Special routes of U.S. Route 129.
- U.S. Route 129 Truck (Blairsville, Georgia) renamed to Special routes of U.S. Route 129.
- U.S. Route 12A (Kalamazoo, Michigan) renamed to M-96 (Michigan highway).
- U.S. Route 12 Alternate (Kalamazoo, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 12 Business (Albion, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 12 Business (Battle Creek, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 12 Business (Eau Claire, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 Business (Jackson, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 12 Business (Kalamazoo, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 12 Business (Lake Delton, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 Business (Madison, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 Business (Marshall, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 12 Business (Niles, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 12 Business (Sauk Prairie, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 Business (Whitewater, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 Business (Ypsilanti, Michigan) renamed to U.S. Route 12 in Michigan.
- U.S. Route 12 Bypass (Madison, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 12 City (Madison, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 131 Business (Big Rapids, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Cadillac, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Constantine, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Grand Rapids, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Kalamazoo, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Manton, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Business (Three Rivers, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 131 Bypass (Grand Rapids, Michigan) renamed to Business routes of U.S. Route 131.
- U.S. Route 13A (Windsor, North Carolina) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Bethel–Williamston, North Carolina) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Bridgeville, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Camden, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Delmar, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Dover, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Wilmington, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate (Windsor, North Carolina) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Alternate Truck (Bensalem, Pennsylvania) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Accomac–Onley, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Bethel, North Carolina) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Bridgeville, Delaware) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Cheriton, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Chester, Pennsylvania) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Eastville, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Exmore, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Onley–Accomac, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Pocomoke City, Maryland) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Suffolk, Virginia) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Business (Windsor, North Carolina) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Bypass (Chester, Pennsylvania) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Bypass (Marcus Hook, Pennsylvania) renamed to Special routes of U.S. Route 13.
- U.S. Route 13 Bypass (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 13.
- U.S. Route 141 Business (Coleman–Pound, Wisconsin) renamed to U.S. Route 141.
- U.S. Route 141 Business (Manitowoc, Wisconsin) renamed to U.S. Route 141.
- U.S. Route 141 Business (Sheboygan, Wisconsin) renamed to U.S. Route 141.
- U.S. Route 143 renamed to U.S. Route 31E.
- U.S. Route 143 in Kentucky renamed to U.S. Route 31E.
- U.S. Route 14C renamed to U.S. Route 14 in Wisconsin.
- U.S. Route 14 Alternate (Spearfish–Sturgis, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Alternate (Wyoming) renamed to U.S. Route 14 in Wyoming.
- U.S. Route 14 Business (Dodge Center, Minnesota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Business (Huron, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Business (Janesville, Wisconsin) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Business (Madison, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 14 Business (Rapid City, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Business (Sheridan, Wyoming) renamed to Business routes of Interstate 90.
- U.S. Route 14 Business (Woodstock, Illinois) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Bypass (Brookings, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 Bypass (Pierre, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 City (Janesville, Wisconsin) renamed to Special routes of U.S. Route 14.
- U.S. Route 14 City (Madison, Wisconsin) renamed to Business routes of U.S. Route 12 in Wisconsin.
- U.S. Route 14 Truck (Pierre, South Dakota) renamed to Special routes of U.S. Route 14.
- U.S. Route 15-501 in North Carolina renamed to U.S. Route 15 in North Carolina.
- U.S. Route 150 Business (Champaign, Illinois) renamed to U.S. Route 150 in Illinois.
- U.S. Route 150 Business (Peoria, Illinois) renamed to U.S. Route 150 in Illinois.
- U.S. Route 150 Business (Springfield, Kentucky) renamed to U.S. Route 150.
- U.S. Route 150 Bypass (Danville, Kentucky) renamed to U.S. Route 150.
- U.S. Route 150 City (Peoria, Illinois) renamed to U.S. Route 150 in Illinois.
- U.S. Route 150 Truck (Bardstown, Kentucky) renamed to U.S. Route 31E.
- U.S. Route 151 Business (Beaver Dam, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Cascade, Iowa) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Cedar Rapids, Iowa) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Columbus, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Mineral Point, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Monticello, Iowa) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Mount Horeb, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Platteville, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Sun Prairie, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Verona, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 151 Business (Waupun, Wisconsin) renamed to Special routes of U.S. Route 151.
- U.S. Route 152 renamed to U.S. Route 231 in Indiana.
- U.S. Route 154 renamed to U.S. Route 400.
- U.S. Route 154 Spur (Dodge City, Kansas) renamed to K-129 (1980–1997 Kansas highway).
- U.S. Route 155 renamed to K-156 (Kansas highway).
- U.S. Route 158 Alternate (Gatesville, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Alternate (Henderson, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Alternate (Oxford, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Alternate (Warrenton, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Gatesville, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Henderson, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Kill Devil Hills, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Murfreesboro, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Oxford, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Warrenton, North Carolina) renamed to U.S. Route 158.
- U.S. Route 158 Business (Winston-Salem, North Carolina) renamed to U.S. Route 158.
- U.S. Route 15A (Chapel Hill, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15A (Sanford, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Chapel Hill, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Farmville, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Sanford, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Sumter-Society Hill, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Sumter–Society Hill, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Alternate (Walterboro, South Carolina–Creedmoor, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Bennettsville, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Chapel Hill, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Culpeper, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Durham, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Emmitsburg, Maryland) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Farmville, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Gettysburg, Pennsylvania) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Hartsville, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Keysville, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Laurinburg, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Leesburg, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Mansfield, Pennsylvania) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Remington, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Sanford, North Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Shamokin Dam, Pennsylvania) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Business (Warrenton, Virginia) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Connector (Santee, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Connector (Summerton, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 15 Connector (Sumter, South Carolina) renamed to Special routes of U.S. Route 15.
- U.S. Route 160 Business (Bayfield, Colorado) renamed to U.S. Route 160.
- U.S. Route 160 Business (Mancos, Colorado) renamed to U.S. Route 160.
- U.S. Route 163 (1930s) renamed to Iowa Highway 163.
- U.S. Route 163 (Iowa) renamed to Iowa Highway 163.
- U.S. Route 164 (1960s) renamed to U.S. Route 160.
- U.S. Route 164 (Arizona-New Mexico-Colorado) renamed to U.S. Route 160.
- U.S. Route 164 (Arizona–Colorado) renamed to U.S. Route 160.
- U.S. Route 164 (Oklahoma-Texas) renamed to U.S. Route 60.
- U.S. Route 164 (Texas–Oklahoma) renamed to U.S. Route 60.
- U.S. Route 164 (pre-1930) renamed to U.S. Route 60.
- U.S. Route 165B (Gillett, Arkansas) renamed to U.S. Route 165.
- U.S. Route 165 Business renamed to U.S. Route 165.
- U.S. Route 165 Business (Alexandria, Louisiana) renamed to U.S. Route 165.
- U.S. Route 165 Business (Gillett, Arkansas) renamed to U.S. Route 165.
- U.S. Route 165 Business (Monroe, Louisiana) renamed to U.S. Route 165.
- U.S. Route 165 Bypass (Alexandria, Louisiana) renamed to U.S. Route 165.
- U.S. Route 166 Business (Sedan, Kansas) renamed to U.S. Route 166.
- U.S. Route 167 Business (Alexandria, Louisiana) renamed to U.S. Route 167.
- U.S. Route 167 Business (El Dorado, Arkansas) renamed to U.S. Route 167.
- U.S. Route 167 Business (Sheridan, Arkansas) renamed to U.S. Route 167.
- U.S. Route 167 Business (Thornton, Arkansas) renamed to U.S. Route 167.
- U.S. Route 168 renamed to U.S. Route 150.
- U.S. Route 169 Alternate (Nowata, Oklahoma) renamed to Special routes of U.S. Route 169.
- U.S. Route 169 Alternate (Oklahoma) renamed to Special routes of U.S. Route 169.
- U.S. Route 169 Business (Fort Dodge, Iowa) renamed to Special routes of U.S. Route 169.
- U.S. Route 169 Business (Garnett, Kansas) renamed to Special routes of U.S. Route 169.
- U.S. Route 169 Spur (Smithville, Missouri) renamed to Special routes of U.S. Route 169.
- U.S. Route 16A (Farmington, Michigan) renamed to U.S. Route 16 in Michigan.
- U.S. Route 16 Alternate (Wall–Kadoka, South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Business (Farmington, Michigan) renamed to U.S. Route 16 in Michigan.
- U.S. Route 16 Business (Grand Rapids, Michigan) renamed to U.S. Route 16 in Michigan.
- U.S. Route 16 Business (Newcastle, Wyoming) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Business (Rapid City, South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Business (Watertown, Wisconsin) renamed to Wisconsin Highway 16.
- U.S. Route 16 Bypass (Grand Rapids, Michigan) renamed to U.S. Route 16 in Michigan.
- U.S. Route 16 Truck (Hill City, South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Truck (Newcastle, Wyoming) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Truck (Rapid City, South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 16 Truck (South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 17-1 renamed to Special routes of U.S. Route 17.
- U.S. Route 17/92 renamed to U.S. Route 17 in Florida.
- U.S. Route 170 renamed to U.S. Route 29.
- U.S. Route 171 Business (Zwolle, Louisiana) renamed to U.S. Route 171.
- U.S. Route 175 Business (Athens, Texas) renamed to Business routes of U.S. Route 175.
- U.S. Route 175 Business (Crandall, Texas) renamed to Business routes of U.S. Route 175.
- U.S. Route 175 Business (Kemp, Texas) renamed to Business routes of U.S. Route 175.
- U.S. Route 175 Business (Mabank, Texas) renamed to Business routes of U.S. Route 175.
- U.S. Route 175 Business (Poynor, Texas) renamed to Business routes of U.S. Route 175.
- U.S. Route 176 Alternate (Spartanburg, South Carolina) renamed to U.S. Route 176.
- U.S. Route 176 Business (Union, South Carolina) renamed to U.S. Route 176.
- U.S. Route 176 Connector (Union, South Carolina) renamed to U.S. Route 176.
- U.S. Route 176 Connector (Whitmire, South Carolina) renamed to U.S. Route 176.
- U.S. Route 176 Connector 1 (Spartanburg, South Carolina) renamed to U.S. Route 176.
- U.S. Route 176 Connector 2 (Spartanburg, South Carolina) renamed to U.S. Route 176.
- U.S. Route 178 Business (Greenwood, South Carolina) renamed to U.S. Route 178.
- U.S. Route 178 Business (Orangeburg, South Carolina) renamed to U.S. Route 178.
- U.S. Route 178 Connector (Northlake, South Carolina) renamed to U.S. Route 178.
- U.S. Route 178 Connector (Saluda, South Carolina) renamed to U.S. Route 178.
- U.S. Route 17A (Elizabeth City, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17A (Williamston, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17A (Windsor, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Elizabeth City, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Georgia–South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Jacksonville, Florida) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Limehouse, South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Savannah, Georgia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Williamston, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate (Windsor, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Alternate Truck (Summerville, South Carolina) renamed to U.S. Route 17 Alternate.
- U.S. Route 17 Business renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Bolivia, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Chesapeake, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Chocowinity–Washington, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Edenton, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Elizabeth City, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Fredericksburg, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Gloucester Courthouse, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Hertford, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Jacksonville, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Marshall, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Mount Pleasant, South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Myrtle Beach, South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (New Bern, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Saluda, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Shallotte, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (South Mills, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Vanceboro, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Warrenton, Virginia) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Williamston, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business (Wilmington, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Business Truck (Elizabeth City, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Bypass (Elizabeth City, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Bypass (Hampstead, North Carolina) renamed to Hampstead Bypass (North Carolina).
- U.S. Route 17 Bypass (Windsor, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Connector (Murrells Inlet–Garden City, South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Connector (Yemassee, South Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Truck (Kissimmee, Florida) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Truck (Maitland, Florida) renamed to Special routes of U.S. Route 17.
- U.S. Route 17 Truck (Wilmington, North Carolina) renamed to Special routes of U.S. Route 17.
- U.S. Route 180 (1926) renamed to U.S. Route 70.
- U.S. Route 181 Business (Beeville, Texas) renamed to U.S. Route 181.
- U.S. Route 181 Business (Karnes City, Texas)(north) renamed to U.S. Route 181.
- U.S. Route 181 Business (Karnes City, Texas)(south) renamed to U.S. Route 181.
- U.S. Route 181 Business (Kenedy, Texas)(north) renamed to U.S. Route 181.
- U.S. Route 181 Business (Kenedy, Texas)(south) renamed to U.S. Route 181.
- U.S. Route 183 Bypass (Hays, Kansas) renamed to U.S. Route 183 in Kansas.
- U.S. Route 185 renamed to U.S. Route 87.
- U.S. Route 187 renamed to U.S. Route 191.
- U.S. Route 189 (1920s) renamed to Utah State Route 132.
- U.S. Route 189 (1928–1938) renamed to Utah State Route 132.
- U.S. Route 189 (Utah 1920s) renamed to Utah State Route 132.
- U.S. Route 189 Alternate (Utah) renamed to Utah State Route 32.
- U.S. Route 18 Alternate (Milwaukee, Wisconsin) renamed to Special routes of U.S. Route 18.
- U.S. Route 18 Business (Marquette–McGregor, Iowa) renamed to Iowa Highway 76.
- U.S. Route 18 Business (Mason City, Iowa) renamed to Special routes of U.S. Route 18.
- U.S. Route 18 Business (Mount Horeb, Wisconsin) renamed to Special routes of U.S. Route 18.
- U.S. Route 18 Business (Verona, Wisconsin) renamed to Special routes of U.S. Route 18.
- U.S. Route 18 Bypass (Hot Springs, South Dakota) renamed to Special routes of U.S. Route 18.
- U.S. Route 190 Business (Copperas Cove, Texas) renamed to U.S. Route 190.
- U.S. Route 190 Business (Heidenheimer, Texas) renamed to U.S. Route 190.
- U.S. Route 190 Business (Killeen, Texas) renamed to U.S. Route 190.
- U.S. Route 190 Business (Slidell, Louisiana) renamed to U.S. Route 190.
- U.S. Route 190 Bypass (Baton Rouge, Louisiana) renamed to Airline Highway.
- U.S. Route 191 Business (Douglas, Arizona) renamed to U.S. Route 191 in Arizona.
- U.S. Route 191 Spur (Luzena, Arizona) renamed to U.S. Route 191 in Arizona.
- U.S. Route 191 Temporary (Arizona) renamed to U.S. Route 191 in Arizona.
- U.S. Route 191 in Wyoming renamed to U.S. Route 191.
- U.S. Route 193 renamed to Unconstructed state routes in Arizona.
- U.S. Route 195 Spur (Washington) renamed to U.S. Route 195.
- U.S. Route 199 in California renamed to U.S. Route 199.
- U.S. Route 19A (1947–1948 Ela–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19A (1948–1987 Ela–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19A (Asheville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19A (Bryson City-Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19A (Ela-Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19A (Waynesville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Asheville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Brooksville, Florida) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Bryson City-Lake Junaluska) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Bryson City–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Cane River–Elk Park, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Ela–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Prosperity, West Virginia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Alternate (Waynesville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Albany, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Andrews, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Asheville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Atlanta, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Dahlonega, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Griffin, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Lebanon, Virginia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Murphy, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Tazewell, Virginia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Thomasville, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Thomasville–Meigs, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Business (Weaverville, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Bypass (Bryson City–Lake Junaluska) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Bypass (Bryson City–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Bypass (Leesburg, Georgia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Connector (Bryson City, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Spur (Fairmont, West Virginia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Truck (Bristol, Virginia) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Truck (Bryson City–Lake Junaluska, North Carolina) renamed to Special routes of U.S. Route 19.
- U.S. Route 19 Truck (Harlansburg, Pennsylvania) renamed to Special routes of U.S. Route 19.
- U.S. Route 1A (Aroostook County, Maine) renamed to U.S. Route 1A.
- U.S. Route 1A (Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1A (Franklinton, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1A (Milbridge, Maine) renamed to U.S. Route 1A.
- U.S. Route 1A (Portland, Maine) renamed to U.S. Route 1A.
- U.S. Route 1A (Rhode Island) renamed to U.S. Route 1A.
- U.S. Route 1A (Rockland, Maine) renamed to U.S. Route 1A.
- U.S. Route 1A (Stonington, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1A (Whitneyville–Machias, Maine) renamed to U.S. Route 1A.
- U.S. Route 1A (York, Maine) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Acosta Bridge) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Alternate (Branford, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Bridgeport, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Cary–Raleigh, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Darien, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Daytona Beach–St. Augustine, Florida) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Alternate (East Haven, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Franklinton, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Groton, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Henderson, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Jacksonville, Florida) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Alternate (Milford, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Moore County, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Norwalk, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Old Saybrook, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Port Chester, New York) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Raleigh, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Raleigh, North Carolina 1946–1948) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Raleigh, North Carolina 1948–1957) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Sanford, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Southern Pines, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Stamford, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Wake Forest–Youngsville, North Carolina) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate (Washington, D.C.) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Alternate (Waterford, Connecticut) renamed to U.S. Route 1A.
- U.S. Route 1 Alternate Truck (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Alternate Truck (West Grove, Pennsylvania) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Damariscotta, Maine) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Florida City–Homestead, Florida) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Fredericksburg, Virginia) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Henderson, North Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Louisville, Georgia) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Maine) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Penndel, Pennsylvania) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Raleigh, North Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Sanford, North Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (St. Augustine, Florida) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Swainsboro, Georgia) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Wadley, Georgia) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Business (Waycross, Georgia) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Bypass (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Bypass (Washington, D.C.) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Connector (Columbia, South Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Connector (Lexington, South Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Truck (Aiken, South Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Truck (Camden, South Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 1 Truck (Cheraw, South Carolina) renamed to Special routes of U.S. Route 1.
- U.S. Route 201A renamed to U.S. Route 201.
- U.S. Route 202 Alternate Truck (North Wales, Pennsylvania) renamed to Special routes of U.S. Route 202.
- U.S. Route 202 Truck (Norristown, Pennsylvania) renamed to Special routes of U.S. Route 202.
- U.S. Route 206 Bypass (Hillsborough, New Jersey) renamed to U.S. Route 206.
- U.S. Route 208 renamed to Minnesota State Highway 210.
- U.S. Route 209 Business (Pennsylvania) renamed to U.S. Route 209.
- U.S. Route 209 Truck renamed to U.S. Route 209.
- U.S. Route 209 Truck (East Stroudsburg–Marshalls Creek, Pennsylvania) renamed to U.S. Route 209.
- U.S. Route 209 Truck (Kresgeville–Brodheadsville, Pennsylvania) renamed to U.S. Route 209.
- U.S. Route 209 Truck (Pottsville–Tamaqua, Pennsylvania) renamed to U.S. Route 209.
- U.S. Route 20A (Eastern Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 20.
- U.S. Route 20A (Western Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 20.
- U.S. Route 20N renamed to U.S. Route 20 in Ohio.
- U.S. Route 20S renamed to U.S. Route 20A (Ohio).
- U.S. Route 20S (Ohio) renamed to U.S. Route 20A (Ohio).
- U.S. Route 20 Alternate (Eastern Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Alternate (Idaho) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Alternate (Indiana) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Alternate (Western Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Bend, Oregon) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Casper, Wyoming) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Chicago, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Elgin, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Fort Dodge, Iowa) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Freeport, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Idaho Falls, Idaho) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Rockford, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Sioux City, Iowa) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (South Bend, Indiana) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (St. Anthony, Idaho) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Business (Toledo, Oregon) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Bypass (South Bend, Indiana) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 City (Chicago, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Toll Business (Chicago, Illinois) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Truck (Osceola–Elkhart, Indiana) renamed to Special routes of U.S. Route 20.
- U.S. Route 20 Truck (Silver Creek, New York) renamed to U.S. Route 20 in New York.
- U.S. Route 211 Business (Luray, Virginia) renamed to U.S. Route 211.
- U.S. Route 211 Business (Warrenton, Virginia) renamed to U.S. Route 211.
- U.S. Route 211 Business (Washington, Virginia) renamed to U.S. Route 211.
- U.S. Route 213 renamed to Maryland Route 213.
- U.S. Route 216 renamed to U.S. Route 16.
- U.S. Route 218 Business (Charles City, Iowa) renamed to U.S. Route 218.
- U.S. Route 218 Business (Mount Pleasant, Iowa) renamed to U.S. Route 218.
- U.S. Route 218 Business (Waverly, Iowa) renamed to U.S. Route 218.
- U.S. Route 219 Alternate (Pennsylvania) renamed to Special routes of U.S. Route 219.
- U.S. Route 219 Business (Meyersdale, Pennsylvania) renamed to Special routes of U.S. Route 219.
- U.S. Route 219 Truck (Ridgway, Pennsylvania) renamed to Special routes of U.S. Route 219.
- U.S. Route 21 Business (Beaufort, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Business (Elkin, North Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Business (Fort Mill, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Business (Orangeburg, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Business (Orangeburg, South Carolina 1950–1967) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Business (Rock Hill, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Bypass (Bluefield, West Virginia) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Connector (Columbia, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Connector (Orangeburg, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Connector (Ridgeway, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Connector (West Columbia, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Spur (Columbia, South Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 21 Truck (Sparta, North Carolina) renamed to Special routes of U.S. Route 21.
- U.S. Route 220 (1925) renamed to U.S. Route 14 in Wyoming.
- U.S. Route 220 (Wyoming) renamed to U.S. Route 14 in Wyoming.
- U.S. Route 220 Alternate renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Alternate (Centre County, Pennsylvania) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Alternate (Roanoke, Virginia) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Alternate (Rocky Mount, Virginia) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Business (Bedford, Pennsylvania) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Business (Blair County, Pennsylvania) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 Truck (Maryland) renamed to Special routes of U.S. Route 220.
- U.S. Route 220 in New York renamed to U.S. Route 220.
- U.S. Route 221 Alternate (Chesnee, South Carolina–Rutherfordton, North Carolina) renamed to Special routes of U.S. Route 221.
- U.S. Route 221 Business (Bedford, Virginia) renamed to Special routes of U.S. Route 221.
- U.S. Route 221 Business (Marion, North Carolina) renamed to Special routes of U.S. Route 221.
- U.S. Route 221 Connector (Chesnee, South Carolina) renamed to Special routes of U.S. Route 221.
- U.S. Route 221 Truck (Linville–Boone, North Carolina) renamed to Special routes of U.S. Route 221.
- U.S. Route 221 Truck (Perry, Florida) renamed to Special routes of U.S. Route 221.
- U.S. Route 222 Truck renamed to U.S. Route 222.
- U.S. Route 222 in Maryland renamed to U.S. Route 222.
- U.S. Route 222 in Pennsylvania renamed to U.S. Route 222.
- U.S. Route 223 in Ohio renamed to U.S. Route 223.
- U.S. Route 224 in Indiana renamed to U.S. Route 224.
- U.S. Route 224 in Ohio renamed to U.S. Route 224.
- U.S. Route 224 in Pennsylvania renamed to U.S. Route 224.
- U.S. Route 22 Alternate (Bethlehem–Easton, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Alternate (Phillipsburg, New Jersey) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Business (Lewistown, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Business (Monroeville, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Bypass (Easton, Pennsylvania–Phillipsburg, New Jersey) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Bypass (Harrisburg, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Temporary (Green Tree–Pittsburgh, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 Truck (Pittsburgh, Pennsylvania) renamed to Special routes of U.S. Route 22.
- U.S. Route 22 in West Virginia renamed to U.S. Route 22.
- U.S. Route 230 renamed to Pennsylvania Route 230.
- U.S. Route 231 Alternate (Sylacauga–Pell City, Alabama) renamed to Special routes of U.S. Route 231.
- U.S. Route 23A in North Carolina renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Alternate renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Alternate (Asheville, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Alternate (Canton, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Alternate (Waynesville, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Alternate (Wolf Laurel, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Ann Arbor, Michigan) renamed to Business routes of U.S. Route 23 in Michigan.
- U.S. Route 23 Business (Asheville, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Ashland, Kentucky) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Baldwin–Cornelia, Georgia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Bay City, Michigan) renamed to Business routes of Interstate 75 in Michigan.
- U.S. Route 23 Business (Big Stone Gap–Norton, Virginia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Chillicothe, Ohio) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Cochran, Georgia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Fenton, Michigan) renamed to Business routes of U.S. Route 23 in Michigan.
- U.S. Route 23 Business (Gate City, Virginia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Hazlehurst, Georgia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Pikeville, Kentucky) renamed to Special routes of U.S. Route 460.
- U.S. Route 23 Business (Pound, Virginia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Rogers City, Michigan) renamed to Business routes of U.S. Route 23 in Michigan.
- U.S. Route 23 Business (Saginaw, Michigan) renamed to Business routes of Interstate 75 in Michigan.
- U.S. Route 23 Business (Sylva, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Waycross, Georgia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Waynesville, North Carolina) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Business (Wise, Virginia) renamed to Special routes of U.S. Route 23.
- U.S. Route 23 Truck (Portsmouth, Ohio) renamed to Special routes of U.S. Route 23.
- U.S. Route 240 Alternate renamed to U.S. Route 240.
- U.S. Route 240 in Maryland renamed to U.S. Route 240.
- U.S. Route 240 in Washington, D.C. renamed to U.S. Route 240.
- U.S. Route 241 (1926) renamed to U.S. Route 41.
- U.S. Route 241 (1930s) renamed to U.S. Route 431.
- U.S. Route 241 (1930s) in Alabama renamed to U.S. Route 431.
- U.S. Route 241 (1930s) in Tennessee renamed to U.S. Route 431.
- U.S. Route 241 (Alabama–Tennessee) renamed to U.S. Route 431.
- U.S. Route 241 (Kentucky-Tennessee) renamed to U.S. Route 41.
- U.S. Route 241 (Tennessee-Alabama) renamed to U.S. Route 431.
- U.S. Route 241 (Tennessee–Kentucky) renamed to U.S. Route 41.
- U.S. Route 241 in Alabama renamed to U.S. Route 431 in Alabama.
- U.S. Route 241 in Kentucky renamed to U.S. Route 41.
- U.S. Route 241 in Tennessee renamed to U.S. Route 241.
- U.S. Route 24A (Michigan) renamed to Interstate 75 in Michigan.
- U.S. Route 24 Business (Kansas City, Missouri) renamed to Special routes of U.S. Route 24.
- U.S. Route 24 Business (Pontiac, Michigan) renamed to U.S. Route 24 in Michigan.
- U.S. Route 250 Business (Charlottesville, Virginia) renamed to U.S. Route 250 in Virginia.
- U.S. Route 250 Truck (Philippi, West Virginia) renamed to U.S. Route 250.
- U.S. Route 250 Truck (Staunton, Virginia) renamed to Virginia State Route 261.
- U.S. Route 258 Alternate (Smithfield, Virginia) renamed to U.S. Route 258.
- U.S. Route 258 Business (Farmville, North Carolina) renamed to U.S. Route 258.
- U.S. Route 258 Business (Franklin, Virginia) renamed to U.S. Route 258.
- U.S. Route 258 Business (Kinston, North Carolina) renamed to U.S. Route 258.
- U.S. Route 258 Business (Smithfield, Virginia) renamed to U.S. Route 258.
- U.S. Route 258 Truck (Snow Hill, North Carolina) renamed to U.S. Route 258.
- U.S. Route 258 in North Carolina renamed to U.S. Route 258.
- U.S. Route 258 in Virginia renamed to U.S. Route 258.
- U.S. Route 259 Business (Kilgore, Texas) renamed to U.S. Route 259.
- U.S. Route 259 Bypass (Idabel, Oklahoma) renamed to U.S. Route 259.
- U.S. Route 259 in Oklahoma renamed to U.S. Route 259.
- U.S. Route 259 in Texas renamed to U.S. Route 259.
- U.S. Route 25A (Erie, Michigan) renamed to U.S. Route 25 in Michigan.
- U.S. Route 25A (Hendersonville, North Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25A (Port Huron, Michigan) renamed to U.S. Route 25 in Michigan.
- U.S. Route 25A in North Carolina renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Alternate (Asheville, North Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Alternate (Hendersonville, North Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Augusta, Georgia) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Augusta, Georgia–North Augusta, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Dry Ridge, Kentucky) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Edgefield, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Greenville, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Greenwood, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Hendersonville, North Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Lexington, Kentucky) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Marshall, North Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (North Augusta, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Port Huron, Michigan) renamed to Business routes of Interstate 94 in Michigan.
- U.S. Route 25 Business (Richmond, Kentucky) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Business (Ware Shoals, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Bypass (Statesboro, Georgia) renamed to Georgia State Route 67.
- U.S. Route 25 Bypass (Waynesboro, Georgia) renamed to Georgia State Route 121.
- U.S. Route 25 Connector (North Augusta, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Connector (Travelers Rest, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 25 Truck (Edgefield, South Carolina) renamed to Special routes of U.S. Route 25.
- U.S. Route 260 renamed to U.S. Route 180.
- U.S. Route 260 in Arizona renamed to U.S. Route 180.
- U.S. Route 260 in New Mexico renamed to U.S. Route 180.
- U.S. Route 264A (Belhaven, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264A (Farmville, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264A (Greenville, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264A (Wilson, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Alternate (Middlesex–Greenville, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Alternate (Wilson–Greenville, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Business (Belhaven, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Business (Greenville, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Business (Wilson, North Carolina) renamed to U.S. Route 264.
- U.S. Route 264 Bypass (Manns Harbor–Manteo, North Carolina) renamed to U.S. Route 264.
- U.S. Route 26N renamed to U.S. Route 26 in Nebraska.
- U.S. Route 26 Business (Casper, Wyoming) renamed to Special routes of U.S. Route 20.
- U.S. Route 26 Business (Douglas, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 26 Business (Ririe, Idaho) renamed to U.S. Route 26 in Idaho.
- U.S. Route 270B (Malvern, Arkansas) renamed to U.S. Route 270.
- U.S. Route 270 (1926) renamed to U.S. Route 70S.
- U.S. Route 270 Business (Hot Springs, Arkansas) renamed to U.S. Route 270.
- U.S. Route 270 in Arkansas renamed to U.S. Route 270.
- U.S. Route 270 in Kansas renamed to U.S. Route 270.
- U.S. Route 270 in Oklahoma renamed to U.S. Route 270.
- U.S. Route 270 in Tennessee renamed to U.S. Route 70S.
- U.S. Route 271 Business (Bogata, Texas) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 Business (Deport, Texas) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 Business (Hugo, Oklahoma) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 Business (Mount Pleasant, Texas) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 Business (Paris, Texas) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 Bypass (Poteau, Oklahoma) renamed to Special routes of U.S. Route 271.
- U.S. Route 271 in Arkansas renamed to U.S. Route 271.
- U.S. Route 271 in Oklahoma renamed to U.S. Route 271.
- U.S. Route 271 in Texas renamed to U.S. Route 271.
- U.S. Route 275 in Missouri renamed to U.S. Route 275.
- U.S. Route 275 in Nebraska renamed to U.S. Route 275.
- U.S. Route 276 Business (Greenville, South Carolina) renamed to U.S. Route 276.
- U.S. Route 276 Business (Greenville, South Carolina 1940s–1970s) renamed to U.S. Route 276.
- U.S. Route 276 Business (Greenville, South Carolina 1983–1984) renamed to U.S. Route 276.
- U.S. Route 276 Connector (Travelers Rest, South Carolina) renamed to U.S. Route 276.
- U.S. Route 276 in North Carolina renamed to U.S. Route 276.
- U.S. Route 276 in South Carolina renamed to U.S. Route 276.
- U.S. Route 276 in Tennessee renamed to U.S. Route 276.
- U.S. Route 277 Business (Holliday, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 277 in Oklahoma renamed to U.S. Route 277.
- U.S. Route 277 in Texas renamed to U.S. Route 277.
- U.S. Route 278B (Camden, Arkansas) renamed to Special routes of U.S. Route 278.
- U.S. Route 278B (Hope, Arkansas) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Business (Hilton Head Island, South Carolina) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Business (Piedmont, Alabama) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Business (Rockmart, Georgia) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Business (Warren, Arkansas) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Bypass (Warrenton, Georgia) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Connector (Ridgeland, South Carolina) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 Truck (Warrenton, Georgia) renamed to Special routes of U.S. Route 278.
- U.S. Route 278 in Mississippi renamed to U.S. Route 278.
- U.S. Route 27A (Alma, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Alternate (Florida) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Alternate (Haines City, Florida) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Alternate (Lake Weir, Florida) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Alternate (Sebring–Avon Park, Florida) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Alternate (Williston–Perry, Florida) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Alma, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Attapulgus, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Bainbridge, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Blakely, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Bremen, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Buchanan, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Cedartown, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Charlotte, Michigan) renamed to Business routes of Interstate 69 in Michigan.
- U.S. Route 27 Business (Clare, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Cuthbert, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Cynthiana, Kentucky) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Harrison, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Ithaca, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (LaFayette, Georgia) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (Lansing, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Marshall, Michigan) renamed to U.S. Route 27 in Michigan.
- U.S. Route 27 Business (Mount Pleasant, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Mt. Pleasant, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (Nicholasville, Kentucky) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Business (St. Johns, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Business (St. Louis, Michigan) renamed to Business routes of U.S. Route 127 in Michigan.
- U.S. Route 27 Connector (Cynthiana, Kentucky) renamed to Special routes of U.S. Route 27.
- U.S. Route 27 Truck (Lansing, Michigan) renamed to U.S. Route 27 in Michigan.
- U.S. Route 280 in Alabama renamed to U.S. Route 280.
- U.S. Route 280 in Georgia renamed to U.S. Route 280.
- U.S. Route 281S renamed to U.S. Route 281 in North Dakota.
- U.S. Route 281 Alternate (Great Bend, Kansas) renamed to U.S. Route 281 in Kansas.
- U.S. Route 281 Bypass (Great Bend, Kansas) renamed to U.S. Route 281.
- U.S. Route 281 in Nebraska renamed to U.S. Route 281.
- U.S. Route 281 in Oklahoma renamed to U.S. Route 281.
- U.S. Route 281 in South Dakota renamed to U.S. Route 281.
- U.S. Route 283 Spur (WaKeeney, Kansas) renamed to U.S. Route 283 in Kansas.
- U.S. Route 283 in Nebraska renamed to U.S. Route 283.
- U.S. Route 283 in Oklahoma renamed to U.S. Route 283.
- U.S. Route 285 (1926) renamed to U.S. Route 287.
- U.S. Route 287 Business (Corsicana, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Business (Electra, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Business (Grapeland, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Business (Midlothian, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Business (Vernon, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Business (Waxahachie, Texas) renamed to Business routes of U.S. Route 287 in Texas.
- U.S. Route 287 Bypass (Rawlins, Wyoming) renamed to U.S. Route 287.
- U.S. Route 287 in Wyoming renamed to U.S. Route 287.
- U.S. Route 290 Business (Cypress, Texas) renamed to U.S. Route 290.
- U.S. Route 290 Business (Hempstead–Hockley, Texas) renamed to U.S. Route 290.
- U.S. Route 295 renamed to Washington State Route 127.
- U.S. Route 299 renamed to California State Route 299.
- U.S. Route 29A (Bessemer City, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29A (Greensboro, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29A (Lexington, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29A (Reidsville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29A (Salisbury, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29A (Thomasville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Bessemer City, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Danville, Virginia 1936–1941) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Danville, Virginia 1941–1970) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Greensboro, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Greenville, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (High Point, North Carolina 1934–1948) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (High Point, North Carolina 1948–1991) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Kannapolis, North Carolina 1938–1940) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Kannapolis, North Carolina 1940–1948) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Kannapolis, North Carolina 1948–1997) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Lexington, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Lynchburg, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Palmetto–Red Oak, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Reidsville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Salisbury, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Spartanburg–Blacksburg, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Alternate (Thomasville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Anderson, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Auburn-Winder, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Charlotte, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Charlottesville, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Chatham, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Culpeper, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Danville, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Danville, Virginia 1970–1998) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Decatur, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Greenville, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Gretna, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Hurt–Altavista, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (LaGrange, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lawrenceville–Athens, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lawrenceville–Winder, Georgia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lexington, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lovingston, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lynchburg, Virginia 1971–2005) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Lynchburg–Amherst, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Madison, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Reidsville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Reidsville, North Carolina 1960–1973) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Remington, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Salisbury, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Thomasville, North Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Business (Warrenton, Virginia) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Connector (Greenville, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Connector (Spartanburg, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Connector (Wade Hampton, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Connector (Williamston, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Spur (Greenville, South Carolina) renamed to Special routes of U.S. Route 29.
- U.S. Route 29 Truck (Union Springs, Alabama) renamed to Special routes of U.S. Route 29.
- U.S. Route 2A (Aroostook County, Maine) renamed to Special routes of U.S. Route 2.
- U.S. Route 2A (Orono–Old Town, Maine) renamed to Special routes of U.S. Route 2.
- U.S. Route 2N renamed to U.S. Route 2 in North Dakota.
- U.S. Route 2S renamed to U.S. Route 2 in North Dakota.
- U.S. Route 2 Business (Grand Forks, North Dakota) renamed to Special routes of U.S. Route 2.
- U.S. Route 2 Business (Ironwood, Michigan) renamed to U.S. Route 2 in Michigan.
- U.S. Route 2 Business (Minot, North Dakota) renamed to Special routes of U.S. Route 2.
- U.S. Route 2 Business (Montpelier, Vermont) renamed to Special routes of U.S. Route 2.
- U.S. Route 2 Business (Williston, North Dakota) renamed to Special routes of U.S. Route 2.
- U.S. Route 2 Business (Wisconsin–Michigan) renamed to U.S. Route 2 in Michigan.
- U.S. Route 2 Truck (St. Johnsbury, Vermont) renamed to Special routes of U.S. Route 2.
- U.S. Route 2 Truck (Superior, Wisconsin) renamed to Special routes of U.S. Route 2.
- U.S. Route 301A (Fayetteville, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301A (Halifax, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301A (Lumberton, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301A (Rocky Mount, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301A (Wilson, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301N renamed to U.S. Route 301 in Delaware.
- U.S. Route 301S renamed to U.S. Route 301 in Delaware.
- U.S. Route 301 Alternate (Petersburg, Virginia) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Business (Dade City, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 301 Business (Elm City, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Business (Fayetteville, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Business (Lumberton, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Business (Sylvania, Georgia) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Business (Wilson, North Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Bypass (Statesboro, Georgia) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Connector 1 (Alcolu, South Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Connector 2 (Alcolu, South Carolina) renamed to Special routes of U.S. Route 301.
- U.S. Route 301 Truck (Dade City, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 301 Truck (Delaware) renamed to Special routes of U.S. Route 301.
- U.S. Route 302 Business (Bartlett, New Hampshire) renamed to New Hampshire Route 16.
- U.S. Route 302 in Maine renamed to U.S. Route 302.
- U.S. Route 302 in New Hampshire renamed to U.S. Route 302.
- U.S. Route 302 in Vermont renamed to U.S. Route 302.
- U.S. Route 309 Bypass (Allentown, Pennsylvania) renamed to Pennsylvania Route 309.
- U.S. Route 309 Truck (Philadelphia, Pennsylvania) renamed to Pennsylvania Route 309.
- U.S. Route 30N (Idaho-Wyoming) renamed to U.S. Route 30.
- U.S. Route 30N (Idaho–Oregon) renamed to Special routes of U.S. Route 95.
- U.S. Route 30N (Idaho–Wyoming) renamed to U.S. Route 30.
- U.S. Route 30N (Ohio) renamed to U.S. Route 30 in Ohio.
- U.S. Route 30N (Oregon–Idaho) renamed to Special routes of U.S. Route 95.
- U.S. Route 30N (Wyoming-Idaho) renamed to U.S. Route 30.
- U.S. Route 30N in Idaho renamed to U.S. Route 30N.
- U.S. Route 30S (Idaho-Utah-Wyoming) renamed to Special routes of U.S. Route 30.
- U.S. Route 30S (Idaho–Wyoming) renamed to Special routes of U.S. Route 30.
- U.S. Route 30S (Nebraska-Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30S (Nebraska–Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30S (Ohio) renamed to Ohio State Route 309.
- U.S. Route 30S (Oregon) renamed to Oregon Route 201.
- U.S. Route 30S (Wyoming-Utah-Idaho) renamed to U.S. Route 30.
- U.S. Route 30 Alternate (Clinton, Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Dalton, Ohio) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Nebraska–Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Ogden–Marshalltown, Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Portland, Oregon) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Alternate (Sterling–Chicago, Illinois) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Aurora, Illinois) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Bedford, Pennsylvania) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Everett, Pennsylvania) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Green River, Wyoming) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Marshalltown, Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Ontario, Oregon) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Portland, Oregon) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Rawlins, Wyoming) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Rock Springs, Wyoming) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (St. Helens, Oregon) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Toledo–Tama, Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business (Van Wert, Ohio) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Business Alternate Truck (Downingtown, Pennsylvania) renamed to U.S. Route 30 Business (Chester County, Pennsylvania).
- U.S. Route 30 Bypass (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Bypass (Portland, Oregon) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Emergency (Cedar Rapids, Iowa) renamed to Special routes of U.S. Route 30.
- U.S. Route 30 Toll (Chicago, Illinois) renamed to Interstate 88 (Illinois).
- U.S. Route 30 Truck (Allegheny County, Pennsylvania) renamed to Special routes of U.S. Route 30.
- U.S. Route 310 in Montana renamed to U.S. Route 310.
- U.S. Route 310 in Wyoming renamed to U.S. Route 310.
- U.S. Route 311 (1927) in Virginia renamed to U.S. Route 311.
- U.S. Route 311 (Virginia 1926) renamed to U.S. Route 220 in Virginia.
- U.S. Route 312 renamed to Montana Highway 59.
- U.S. Route 312 in Montana renamed to Montana Highway 59.
- U.S. Route 312 in Wyoming renamed to Montana Highway 59.
- U.S. Route 319 Business (Moultrie, Georgia) renamed to U.S. Route 319.
- U.S. Route 319 in Florida renamed to U.S. Route 319.
- U.S. Route 319 in Georgia renamed to U.S. Route 319.
- U.S. Route 31A (Muskegon, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31A Business (Lewisburg, Tennessee) renamed to U.S. Route 31A.
- U.S. Route 31EX (Mount Washington, Kentucky) renamed to U.S. Route 31E.
- U.S. Route 31E Business (Glasgow, Kentucky) renamed to U.S. Route 31E.
- U.S. Route 31E Bypass (Hendersonville, Tennessee) renamed to Tennessee State Route 386.
- U.S. Route 31E Truck (Bardstown, Kentucky) renamed to U.S. Route 31E.
- U.S. Route 31W Business (West Point, Kentucky) renamed to U.S. Route 31W.
- U.S. Route 31W Bypass (Elizabethtown, Kentucky) renamed to U.S. Route 31W.
- U.S. Route 31W Truck (Elizabethtown, Kentucky) renamed to U.S. Route 31W.
- U.S. Route 31 Alternate (Ludington, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Alternate (Plymouth, Indiana) renamed to Special routes of U.S. Route 31.
- U.S. Route 31 Alternate (Seymour–Columbus, Indiana) renamed to Special routes of U.S. Route 31.
- U.S. Route 31 Business (Hart, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Holland, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Ludington, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Muskegon, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Niles, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Pentwater, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Peru, Indiana) renamed to Special routes of U.S. Route 31.
- U.S. Route 31 Business (South Bend, Indiana) renamed to Special routes of U.S. Route 31.
- U.S. Route 31 Business (South Haven, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Business (Whitehall–Montague, Michigan) renamed to Business routes of U.S. Route 31 in Michigan.
- U.S. Route 31 Emergency (Grand Haven, Michigan) renamed to Permanently signed detour route.
- U.S. Route 31 Truck (Franklin, Tennessee) renamed to Tennessee State Route 397.
- U.S. Route 320 renamed to U.S. Route 26.
- U.S. Route 321A (Granite Falls-Lenoir, North Carolina) renamed to U.S. Route 321.
- U.S. Route 321A (Lenoir, North Carolina) renamed to U.S. Route 321.
- U.S. Route 321A (Lincolnton, North Carolina) renamed to U.S. Route 321.
- U.S. Route 321A in North Carolina renamed to U.S. Route 321.
- U.S. Route 321 Business (Chester, South Carolina) renamed to U.S. Route 321.
- U.S. Route 321 Business (Dallas–Hickory, North Carolina) renamed to U.S. Route 321.
- U.S. Route 321 Business (Newton, North Carolina) renamed to U.S. Route 321.
- U.S. Route 321 Business (Winnsboro, South Carolina) renamed to U.S. Route 321.
- U.S. Route 321 Business (York, South Carolina) renamed to U.S. Route 321.
- U.S. Route 321 Truck (Greeneville, Tennessee) renamed to U.S. Route 321.
- U.S. Route 322 Alternate Truck (Downingtown, Pennsylvania) renamed to Special routes of U.S. Route 322.
- U.S. Route 322 Business (Mullica Hill, New Jersey) renamed to Special routes of U.S. Route 322.
- U.S. Route 322 Truck (Downingtown, Pennsylvania) renamed to Special routes of U.S. Route 322.
- U.S. Route 322 in Ohio renamed to U.S. Route 322.
- U.S. Route 330 renamed to Illinois Route 38.
- U.S. Route 331 (1926) renamed to U.S. Route 29.
- U.S. Route 331 in Florida renamed to U.S. Route 331.
- U.S. Route 33 Business (Elkton, Virginia) renamed to U.S. Route 33 in Virginia.
- U.S. Route 33 Business (Stanardsville, Virginia) renamed to U.S. Route 33 in Virginia.
- U.S. Route 340 in Maryland renamed to U.S. Route 340.
- U.S. Route 340 in Virginia renamed to U.S. Route 340.
- U.S. Route 340 in West Virginia renamed to U.S. Route 340.
- U.S. Route 341 Business (Eastman, Georgia) renamed to Georgia State Route 27.
- U.S. Route 341 Business (Hawkinsville, Georgia) renamed to U.S. Route 341.
- U.S. Route 341 Bypass (Perry, Georgia) renamed to U.S. Route 341.
- U.S. Route 34 Business (Chariton, Iowa) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Estes Park, Colorado) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Fairfield, Iowa) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Glenwood, Iowa) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Greeley, Colorado) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Ottumwa, Iowa) renamed to Special routes of U.S. Route 34.
- U.S. Route 34 Business (Westwood–Mount Pleasant, Iowa) renamed to Special routes of U.S. Route 34.
- U.S. Route 35 Business (Xenia, Ohio) renamed to U.S. Route 35.
- U.S. Route 35 Spur (Teays Valley, West Virginia) renamed to U.S. Route 35.
- U.S. Route 35 in Ohio renamed to U.S. Route 35.
- U.S. Route 360 Business (Amelia Court House, Virginia) renamed to U.S. Route 360.
- U.S. Route 360 Business (Burkeville, Virginia) renamed to U.S. Route 360.
- U.S. Route 360 Business (Keysville, Virginia) renamed to U.S. Route 360.
- U.S. Route 360 Business (Mechanicsville, Virginia) renamed to U.S. Route 360.
- U.S. Route 366 (1926) renamed to U.S. Route 366 (1927–1932).
- U.S. Route 366 (1927–1932) in New Mexico renamed to U.S. Route 366 (1927–1932).
- U.S. Route 366 (1930s) renamed to U.S. Route 366 (1932–1939).
- U.S. Route 366 (1932–1939) in New Mexico renamed to U.S. Route 366 (1932–1939).
- U.S. Route 366 in New Mexico renamed to U.S. Route 366 (1932–1939).
- U.S. Route 366 in Texas renamed to U.S. Route 366 (1927–1932).
- U.S. Route 36 Business (Brookfield, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Cameron, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Chillicothe, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Clarence, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Hamilton, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Hannibal, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Macon, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Monroe City, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (Shelbina, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Business (St. Joseph, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 36 Spur (Macon, Missouri) renamed to Special routes of U.S. Route 36 in Missouri.
- U.S. Route 37 renamed to U.S. Route 31E.
- U.S. Route 371 (1930s) renamed to Minnesota State Highway 371.
- U.S. Route 371 in Arkansas renamed to U.S. Route 371.
- U.S. Route 371 in Louisiana renamed to U.S. Route 371.
- U.S. Route 377 in Texas renamed to U.S. Route 377.
- U.S. Route 378 Business (Lake City, South Carolina) renamed to U.S. Route 378.
- U.S. Route 378 Business (Sumter, South Carolina) renamed to U.S. Route 378.
- U.S. Route 378 Truck (Conway, South Carolina) renamed to U.S. Route 378.
- U.S. Route 378 in Georgia renamed to U.S. Route 378.
- U.S. Route 378 in South Carolina renamed to U.S. Route 378.
- U.S. Route 38 renamed to U.S. Route 6.
- U.S. Route 380 Business (Decatur, Texas) renamed to U.S. Route 380.
- U.S. Route 380 Business (Floyd, Texas) renamed to U.S. Route 380.
- U.S. Route 380 in New Mexico renamed to U.S. Route 380.
- U.S. Route 380 in Texas renamed to U.S. Route 380.
- U.S. Route 383 in Kansas renamed to U.S. Route 383.
- U.S. Route 383 in Nebraska renamed to U.S. Route 383.
- U.S. Route 385 (1926) renamed to U.S. Route 87.
- U.S. Route 385 Truck (Hill City, South Dakota) renamed to Special routes of U.S. Route 16.
- U.S. Route 385 in New Mexico renamed to U.S. Route 87.
- U.S. Route 385 in Oklahoma renamed to U.S. Route 385.
- U.S. Route 385 in South Dakota renamed to U.S. Route 385.
- U.S. Route 393 renamed to U.S. Route 491.
- U.S. Route 395 Alternate (Nevada) renamed to U.S. Route 395 Alternate.
- U.S. Route 395 Business (Nevada) renamed to U.S. Route 395 Business.
- U.S. Route 395 in Oregon renamed to U.S. Route 395.
- U.S. Route 3 Business (Concord, New Hampshire) renamed to U.S. Route 3.
- U.S. Route 3 Business (Laconia, New Hampshire) renamed to U.S. Route 3.
- U.S. Route 3 Bypass (Concord, New Hampshire) renamed to U.S. Route 3.
- U.S. Route 3 Bypass (Nashua, New Hampshire) renamed to U.S. Route 3.
- U.S. Route 400 in Colorado renamed to U.S. Route 400.
- U.S. Route 400 in Kansas renamed to U.S. Route 400.
- U.S. Route 400 in Missouri renamed to U.S. Route 400.
- U.S. Route 401A (Laurinburg, North Carolina) renamed to Special routes of U.S. Route 401.
- U.S. Route 401 (1925) renamed to U.S. Route 15.
- U.S. Route 401 (1926) renamed to U.S. Route 58.
- U.S. Route 401 (1927) renamed to U.S. Route 58.
- U.S. Route 401 (1930s) renamed to U.S. Route 401.
- U.S. Route 401 Business (Bennettsville, South Carolina) renamed to Special routes of U.S. Route 401.
- U.S. Route 401 Business (Rolesville, North Carolina) renamed to Special routes of U.S. Route 401.
- U.S. Route 401 in North Carolina renamed to U.S. Route 401.
- U.S. Route 401 in South Carolina renamed to U.S. Route 401.
- U.S. Route 401 in Virginia renamed to U.S. Route 58.
- U.S. Route 40N renamed to U.S. Route 40.
- U.S. Route 40S renamed to U.S. Route 40.
- U.S. Route 40 Alternate renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (California–Nevada) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (East St. Louis–Collinsville, Illinois) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Greenville–Vandalia, Illinois) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Junction City–Grandview Plaza, Kansas) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Kansas City, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Salt Lake City, Utah) renamed to Utah State Route 186.
- U.S. Route 40 Alternate (St. Louis, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Uniontown, Pennsylvania) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Alternate (Washington, Pennsylvania) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (Brownsville, Pennsylvania) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (Columbia, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (East St. Louis–Collinsville, Illinois) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (Junction City–Grandview Plaza, Kansas) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (Russell, Kansas) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (Uniontown, Pennsylvania) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Business (WaKeeney, Kansas) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Bypass (St. Louis, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 City (East St. Louis–Collinsville, Illinois) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 City (Kansas City, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Optional (Kansas City, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Thru (Washington, Pennsylvania) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Truck (Baltimore, Maryland) renamed to Special routes of U.S. Route 40.
- U.S. Route 40 Truck (St. Louis, Missouri) renamed to Special routes of U.S. Route 40.
- U.S. Route 410 in Idaho renamed to U.S. Route 410.
- U.S. Route 410 in Washington renamed to U.S. Route 410.
- U.S. Route 411 (1926) renamed to U.S. Route 58.
- U.S. Route 411 (1930s) renamed to U.S. Route 220 in North Carolina.
- U.S. Route 411 in Alabama renamed to U.S. Route 411.
- U.S. Route 411 in Georgia renamed to U.S. Route 411.
- U.S. Route 411 in North Carolina renamed to U.S. Route 220 in North Carolina.
- U.S. Route 411 in Tennessee renamed to U.S. Route 411.
- U.S. Route 411 in Virginia renamed to U.S. Route 411.
- U.S. Route 412B (Hindsville, Arkansas) renamed to Special routes of U.S. Route 412.
- U.S. Route 412B (Huntsville, Arkansas) renamed to Special routes of U.S. Route 412.
- U.S. Route 412 Alternate (Oklahoma) renamed to Special routes of U.S. Route 412.
- U.S. Route 412 Business (Hindsville, Arkansas) renamed to Special routes of U.S. Route 412.
- U.S. Route 412 Business (Huntsville, Arkansas) renamed to Special routes of U.S. Route 412.
- U.S. Route 412 Scenic renamed to Special routes of U.S. Route 412.
- U.S. Route 412 in New Mexico renamed to U.S. Route 412.
- U.S. Route 41A Bypass (Clarksville, Tennessee) renamed to U.S. Route 41 Alternate (Tennessee–Kentucky).
- U.S. Route 41A in Tennessee renamed to U.S. Route 41 Alternate (Tennessee–Kentucky).
- U.S. Route 41E (Tennessee–Kentucky) renamed to U.S. Route 41.
- U.S. Route 41W (Tennessee–Kentucky) renamed to U.S. Route 41.
- U.S. Route 41 Alternate (Atlanta–Marietta, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Alternate (Madisonville–Henderson, Kentucky) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Atlanta, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Baraga, Michigan) renamed to U.S. Route 41 in Michigan.
- U.S. Route 41 Business (Bradenton, Florida) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Fort Myers, Florida) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Griffin, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Ishpeming–Negaunee, Michigan) renamed to M-28 Business (Ishpeming–Negaunee, Michigan).
- U.S. Route 41 Business (Macon, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Oconto, Wisconsin) renamed to Business routes of U.S. Route 41 in Wisconsin.
- U.S. Route 41 Business (Peshtigo, Wisconsin) renamed to Business routes of U.S. Route 41 in Wisconsin.
- U.S. Route 41 Business (Tampa, Florida) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Valdosta, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Business (Venice, Florida) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Bypass (Atlanta–Marietta, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Temporary (Atlanta–Marietta, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Toll (Chicago, Illinois) renamed to Tri-State Tollway.
- U.S. Route 41 Truck (Hopkinsville, Kentucky) renamed to Special routes of U.S. Route 41.
- U.S. Route 41 Truck (Ringgold, Georgia) renamed to Special routes of U.S. Route 41.
- U.S. Route 420 renamed to U.S. Route 14 in Wyoming.
- U.S. Route 420 (1925) renamed to U.S. Route 730.
- U.S. Route 420 (Oregon–Washington) renamed to U.S. Route 730.
- U.S. Route 420 in Oregon renamed to U.S. Route 730.
- U.S. Route 420 in Washington renamed to U.S. Route 730.
- U.S. Route 421A (Clinton, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 421A (North Wilkesboro, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 421 Business (Clinton, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 421 Business (North Wilkesboro, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 421 Business (Richmond, Kentucky) renamed to Special routes of U.S. Route 25.
- U.S. Route 421 Business (Sanford, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 421 Connector (Sanford, North Carolina) renamed to Special routes of U.S. Route 421.
- U.S. Route 422 Alternate (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 422.
- U.S. Route 422 Business (Indiana, Pennsylvania) renamed to Special routes of U.S. Route 422.
- U.S. Route 422 Business (Kittanning, Pennsylvania) renamed to Special routes of U.S. Route 422.
- U.S. Route 422 Business (New Castle, Pennsylvania) renamed to Special routes of U.S. Route 422.
- U.S. Route 422 Bypass (Philadelphia, Pennsylvania) renamed to Special routes of U.S. Route 422.
- U.S. Route 422 in Ohio renamed to U.S. Route 422.
- U.S. Route 422 in Pennsylvania renamed to U.S. Route 422.
- U.S. Route 425 in Arkansas renamed to U.S. Route 425.
- U.S. Route 425 in Louisiana renamed to U.S. Route 425.
- U.S. Route 425 in Mississippi renamed to U.S. Route 425.
- U.S. Route 430 renamed to Illinois Route 31.
- U.S. Route 431 Truck (Franklin, Tennessee) renamed to Tennessee State Route 397.
- U.S. Route 441 Alternate (Lady Lake–Belleview, Florida) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Alternate (Ocala–Reddick, Florida) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Business (Baldwin–Clarkesville, Georgia) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Business (Baldwin–Hollywood, Georgia) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Business (Commerce, Georgia) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Business (Eatonton, Georgia) renamed to Georgia State Route 24.
- U.S. Route 441 Business (Milledgeville, Georgia) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Business (Watkinsville, Georgia) renamed to Georgia State Route 24.
- U.S. Route 441 Bypass (Dublin, Georgia) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Bypass (Gatlinburg, Tennessee) renamed to Gatlinburg Bypass.
- U.S. Route 441 Bypass (Madison, Georgia) renamed to Georgia State Route 24.
- U.S. Route 441 Truck (Lake City, Florida) renamed to Special routes of U.S. Route 441.
- U.S. Route 441 Truck (Leesburg, Florida) renamed to Special routes of U.S. Route 441.
- U.S. Route 44A renamed to U.S. Route 44.
- U.S. Route 44 in Connecticut renamed to U.S. Route 44.
- U.S. Route 44 in New York renamed to U.S. Route 44.
- U.S. Route 450 renamed to U.S. Route 160.
- U.S. Route 450 in Colorado renamed to U.S. Route 160 in Colorado.
- U.S. Route 45E Business (Martin, Tennessee) renamed to U.S. Route 45E.
- U.S. Route 45W Business (Trenton, Tennessee) renamed to Tennessee State Route 367.
- U.S. Route 45 Alternate (Brooksville–Shannon, Mississippi) renamed to U.S. Route 45 Alternate.
- U.S. Route 45 Business (Paducah, Kentucky) renamed to U.S. Route 45 in Kentucky.
- U.S. Route 45 Bypass (Jackson, Tennessee) renamed to Tennessee State Route 186.
- U.S. Route 45 Bypass (Mayfield, Kentucky) renamed to U.S. Route 45 in Kentucky.
- U.S. Route 460 Business (Paintsville, Kentucky) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Business (Petersburg, Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Business (Pikeville, Kentucky) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Business (Richlands–Cedar Bluff, Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Business (Suffolk, Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Business (Tazewell, Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Bypass renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Bypass (Bedford, Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Bypass (Georgetown, Kentucky) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 Temporary (Bluefield, Virginia–West Virginia) renamed to Special routes of U.S. Route 460.
- U.S. Route 460 in Illinois renamed to U.S. Route 460.
- U.S. Route 460 in Indiana renamed to U.S. Route 460.
- U.S. Route 460 in Missouri renamed to U.S. Route 460.
- U.S. Route 466 (New Mexico–Texas) renamed to U.S. Route 85.
- U.S. Route 466 in Arizona renamed to U.S. Route 93 in Arizona.
- U.S. Route 466 in California renamed to U.S. Route 466.
- U.S. Route 466 in Nevada renamed to U.S. Route 466.
- U.S. Route 470 renamed to U.S. Route 366 (1932–1939).
- U.S. Route 485 renamed to U.S. Route 64.
- U.S. Route 48 (1965) renamed to Interstate 68.
- U.S. Route 48 (1965–1991) renamed to Interstate 68.
- U.S. Route 48 (1969–1989) renamed to Interstate 68.
- U.S. Route 48 (1970s) in Maryland renamed to Interstate 68.
- U.S. Route 48 (1970s) in West Virginia renamed to Interstate 68.
- U.S. Route 48 (West Virginia-Maryland) renamed to Interstate 68.
- U.S. Route 48 (West Virginia–Maryland) renamed to Interstate 68.
- U.S. Route 491 in Colorado renamed to U.S. Route 491.
- U.S. Route 491 in New Mexico renamed to U.S. Route 491.
- U.S. Route 491 in Utah renamed to U.S. Route 491.
- U.S. Route 49E (1930-1936) renamed to U.S. Route 49.
- U.S. Route 49E (1930–1936) renamed to U.S. Route 49.
- U.S. Route 49E Business (Greenwood, Mississippi) renamed to Special routes of U.S. Route 49.
- U.S. Route 49W (1930-1936) renamed to U.S. Route 49.
- U.S. Route 49W (1930–1936) renamed to U.S. Route 49.
- U.S. Route 49 Business (Brookland, Arkansas) renamed to Special routes of U.S. Route 49.
- U.S. Route 49 Business (Hattiesburg, Mississippi) renamed to Special routes of U.S. Route 49.
- U.S. Route 49 Business (Helena–West Helena, Arkansas) renamed to Special routes of U.S. Route 49.
- U.S. Route 49 Business (Jonesboro, Arkansas) renamed to Special routes of U.S. Route 49.
- U.S. Route 49 Business (Paragould, Arkansas) renamed to Special routes of U.S. Route 49.
- U.S. Route 4 Alternate (Andover, Vermont–Boscawen, New Hampshire) renamed to Special routes of U.S. Route 4.
- U.S. Route 4 Alternate (Andover–Boscawen, New Hampshire) renamed to Special routes of U.S. Route 4.
- U.S. Route 4 Alternate (East Northwood–Dover, New Hampshire) renamed to Special routes of U.S. Route 4.
- U.S. Route 4 Alternate (Fair Haven–West Rutland, Vermont) renamed to Special routes of U.S. Route 4.
- U.S. Route 4 Business (Rutland, Vermont) renamed to Special routes of U.S. Route 4.
- U.S. Route 4 Bypass (Concord, New Hampshire) renamed to Special routes of U.S. Route 4.
- U.S. Route 501A (Roxboro, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Alternate (Chapel Hill, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Alternate (Sanford, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Buena Vista, Virginia) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Chapel Hill, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Conway, South Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Marion, South Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Roxboro, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 Business (Sanford, North Carolina) renamed to Special routes of U.S. Route 501.
- U.S. Route 501 in North Carolina renamed to U.S. Route 501.
- U.S. Route 501 in South Carolina renamed to U.S. Route 501.
- U.S. Route 501 in Virginia renamed to U.S. Route 501.
- U.S. Route 50N (Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50S (Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50 Alternate (Athens, Ohio–Ellenboro, West Virginia) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Alternate (California) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Alternate (Dodge City, Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50 Alternate (Garden City, Kansas) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Alternate (Nevada–Utah) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Alternate (Sumner–Lawrenceville, Illinois) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Alternate (Washington, D.C.) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Bedford, Indiana) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Belpre, Ohio) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (California, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Carson City, Nevada) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Dodge City, Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50 Business (Garden City, Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50 Business (Jefferson City, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Jefferson City, Missouri 1964–1975) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Knob Noster, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Lawrenceville, Illinois) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Oakland, California) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Olathe, Colorado) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Ottawa, Kansas) renamed to U.S. Route 50 in Kansas.
- U.S. Route 50 Business (Parkersburg, West Virginia) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Pueblo–Avondale, Colorado) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Sacramento, California) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (St. Louis, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (St. Martins, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Vincennes, Indiana) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Warrensburg, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Business (Washington, Indiana) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Bypass (Cincinnati, Ohio) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Bypass (Dodge City, Kansas) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Bypass (Garden City, Kansas) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Bypass (St. Louis, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Bypass (Washington, D.C.) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 City (St. Louis, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Optional (Kansas–Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Spur (Smithton, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Temporary (Carson City, Nevada) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Temporary (Colton–Castle Gate, Utah) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Temporary (District of Columbia–Maryland) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Truck (Cincinnati, Ohio) renamed to Special routes of U.S. Route 50.
- U.S. Route 50 Truck (St. Louis, Missouri) renamed to Special routes of U.S. Route 50.
- U.S. Route 511 renamed to U.S. Route 11E.
- U.S. Route 511 in Tennessee renamed to U.S. Route 11E.
- U.S. Route 511 in Virginia renamed to U.S. Route 11E.
- U.S. Route 51 Business (Dyersburg, Tennessee) renamed to U.S. Route 51 in Tennessee.
- U.S. Route 51 Business (Ponchatoula–Hammond, Louisiana) renamed to U.S. Route 51 in Louisiana.
- U.S. Route 521 Business (Andrews, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Business (Lancaster, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Bypass (Lancaster, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Connector (Kershaw, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Connector (Sumter, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Truck (Camden, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Truck (Kershaw, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Truck 1 (Camden, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 Truck 2 (Camden, South Carolina) renamed to Special routes of U.S. Route 521.
- U.S. Route 521 in North Carolina renamed to U.S. Route 521.
- U.S. Route 521 in South Carolina renamed to U.S. Route 521.
- U.S. Route 522 Business (Washington, Virginia) renamed to U.S. Route 211.
- U.S. Route 522 in Maryland renamed to U.S. Route 522.
- U.S. Route 522 in Pennsylvania renamed to U.S. Route 522.
- U.S. Route 522 in Virginia renamed to U.S. Route 522.
- U.S. Route 522 in West Virginia renamed to U.S. Route 522.
- U.S. Route 52A (Mount Airy, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52A (Pilot Mountain, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Alternate (Iowa) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Alternate (Mount Airy, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Alternate (Pilot Mountain, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Alternate (Welch, West Virginia) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Albemarle, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Darlington, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Harvey, North Dakota) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Ironton, Ohio) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Minot, North Dakota) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Mount Airy, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Business (Pilot Mountain, North Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Connector (Florence, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Connector (North Charleston, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Spur (Charleston, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Truck (Bluefield, West Virginia) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Truck (Cheraw, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Truck (Florence, South Carolina) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Truck (Jamestown, North Dakota) renamed to Special routes of U.S. Route 52.
- U.S. Route 52 Truck (Williamson, West Virginia) renamed to Special routes of U.S. Route 52.
- U.S. Route 530 renamed to U.S. Route 189.
- U.S. Route 530 (1925) renamed to U.S. Route 30.
- U.S. Route 530 (Idaho–Wyoming) renamed to U.S. Route 30.
- U.S. Route 541 renamed to Special routes of U.S. Route 41.
- U.S. Route 54 Alternate (Jefferson City, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Alamogordo, New Mexico) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (El Paso, Texas) renamed to U.S. Route 54 in Texas.
- U.S. Route 54 Business (Eldon, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Fulton, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Kankakee, Illinois) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Lake Ozark, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Louisiana, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Mexico, Missouri) renamed to Special routes of U.S. Route 54.
- U.S. Route 54 Business (Tucumcari, New Mexico) renamed to New Mexico State Road 237.
- U.S. Route 54 City (Kankakee, Illinois) renamed to Special routes of U.S. Route 54.
- U.S. Route 550 in Colorado renamed to U.S. Route 550.
- U.S. Route 550 in New Mexico renamed to U.S. Route 550.
- U.S. Route 55 (1950s) renamed to U.S. Route 56.
- U.S. Route 55 (Arizona–Wisconsin) renamed to U.S. Route 56.
- U.S. Route 560 renamed to U.S. Route 491.
- U.S. Route 566 renamed to U.S. Route 380.
- U.S. Route 570 renamed to U.S. Route 85.
- U.S. Route 58 Alternate (Portsmouth, Virginia) renamed to Virginia State Route 337 Alternate (Portsmouth).
- U.S. Route 58 Alternate Business (Dryden, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Alternate Business (Norton, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Boydton, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Clarksville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Courtland, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Danville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Dryden, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Emporia, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Ewing–Rose Hill, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Franklin–Carrsville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Gate City, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Hillsville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Lawrenceville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Martinsville, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Meadows of Dan, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (South Hill, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Stuart, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Suffolk, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 58 Business (Virginia Beach, Virginia) renamed to Special routes of U.S. Route 58.
- U.S. Route 59 (1934–1935) renamed to U.S. Route 59.
- U.S. Route 59 (Minnesota 1934–1935) renamed to U.S. Route 59.
- U.S. Route 59 Business (El Campo, Texas) renamed to U.S. Route 59 in Texas.
- U.S. Route 59 Business (Wharton, Texas) renamed to U.S. Route 59 in Texas.
- U.S. Route 59 Bypass (Poteau, Oklahoma) renamed to U.S. Route 59 in Oklahoma.
- U.S. Route 5A (Connecticut–Massachusetts) renamed to Route 159 (Connecticut–Massachusetts).
- U.S. Route 5A (Massachusetts) renamed to Route 159 (Connecticut–Massachusetts).
- U.S. Route 5 Alternate (Berlin, Connecticut) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (Derby Line, Vermont) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (East Hartford–East Windsorhill, Connecticut) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (Lamentation Mountain State Park–Tracy, Connecticut 1937–1941) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (Lamentation Mountain State Park–Tracy, Connecticut 1940s–1950s) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (New Haven, Connecticut 1933–1941) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (New Haven, Connecticut 1941–1966) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (New Haven–Meriden, Connecticut) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (Newport, Vermont) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Alternate (St. Johnsbury, Vermont) renamed to Special routes of U.S. Route 5.
- U.S. Route 5 Bypass (South Deerfield, Massachusetts) renamed to Special routes of U.S. Route 5.
- U.S. Route 6/202 Alternate renamed to Special routes of U.S. Route 6.
- U.S. Route 60/62 in Illinois renamed to U.S. Route 60 in Illinois.
- U.S. Route 601 Business (Concord, North Carolina) renamed to Special routes of U.S. Route 601.
- U.S. Route 601 Business (Kershaw, South Carolina) renamed to Special routes of U.S. Route 601.
- U.S. Route 601 Truck (Camden, South Carolina) renamed to Special routes of U.S. Route 601.
- U.S. Route 601 Truck (Orangeburg, South Carolina) renamed to Special routes of U.S. Route 601.
- U.S. Route 601 in North Carolina renamed to U.S. Route 601.
- U.S. Route 601 in South Carolina renamed to U.S. Route 601.
- U.S. Route 60X renamed to U.S. Route 60 in Arizona.
- U.S. Route 60 (1925) renamed to U.S. Route 66.
- U.S. Route 60 Alternate (Louisville, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Alternate (Norfolk, Virginia) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Cabool, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Clifton Forge, Virginia) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Cloverport, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Dexter, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Lexington, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Mansfield, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Monett, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Mountain Grove, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Neosho, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Paducah, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Ponca City, Oklahoma) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Poplar Bluff, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Rogersville, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Seneca, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Sikeston, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Springfield, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Tonkawa, Oklahoma) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Van Buren, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Verona–Aurora, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Versailles, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Business (Willow Springs, Missouri) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Bypass (Lexington, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Bypass (Owensboro, Kentucky) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Temporary (Arizona) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Truck (Charleston, West Virginia) renamed to Special routes of U.S. Route 60.
- U.S. Route 60 Truck (Richmond, Virginia) renamed to Special routes of U.S. Route 60.
- U.S. Route 611 renamed to Pennsylvania Route 611.
- U.S. Route 611 Alternate (Delaware Water Gap, Pennsylvania) renamed to Pennsylvania Route 611.
- U.S. Route 611 Alternate (Philadelphia, Pennsylvania) renamed to Pennsylvania Route 611.
- U.S. Route 611 in New Jersey renamed to Pennsylvania Route 611.
- U.S. Route 611 in Pennsylvania renamed to Pennsylvania Route 611.
- U.S. Route 61 Business (Bowling Green, Missouri) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Canton, Missouri) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Davenport, Iowa) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Fort Madison, Iowa) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Keokuk, Iowa) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (La Grange, Missouri) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Maquoketa, Iowa) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Muscatine, Iowa) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Natchez, Mississippi) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (New London, Missouri) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Palmyra, Missouri) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (St. Francisville, Louisiana) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Business (Vicksburg, Mississippi) renamed to Special routes of U.S. Route 61.
- U.S. Route 61 Bypass (Baton Rouge, Louisiana) renamed to Special routes of U.S. Route 61.
- U.S. Route 622 renamed to U.S. Route 522.
- U.S. Route 622 in Maryland renamed to U.S. Route 522.
- U.S. Route 622 in Pennsylvania renamed to U.S. Route 522.
- U.S. Route 62B renamed to Special routes of U.S. Route 62.
- U.S. Route 62B (Eureka Springs, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62S (Berryville, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62T (Ohio) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 (1925) renamed to U.S. Route 60.
- U.S. Route 62 Business (Cotter, AR) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Cotter, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Fayetteville, Arkansas) renamed to Arkansas Highway 180.
- U.S. Route 62 Business (Henryetta, Oklahoma) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Mountain Home, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Muskogee, Oklahoma) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Prairie Grove, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Rogers, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Salem, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Sharon, Pennsylvania) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Snyder, Oklahoma) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Tahlequah, Oklahoma) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Business (Yellville, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Spur (Berryville, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Spur (Pyatt, Arkansas) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Temporary (Alliance, Ohio) renamed to U.S. Route 62 in Ohio.
- U.S. Route 62 Truck (Elizabethtown, Kentucky) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 Truck (Lawrenceburg, Kentucky) renamed to Special routes of U.S. Route 62.
- U.S. Route 62 in Illinois renamed to U.S. Route 60 in Illinois.
- U.S. Route 630 renamed to Special routes of U.S. Route 95.
- U.S. Route 630 (Utah) renamed to Special routes of U.S. Route 95.
- U.S. Route 63 Business (Bono, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Hardy, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Hoxie, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Jonesboro, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Marked Tree, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Moberly, Missouri) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (New Hampton, Iowa) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Ottumwa, Iowa) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Pine Bluff, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Warren, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (West Plains, Missouri) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Business (Willow Springs, Missouri) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Spur (Hazen, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 63 Spur (Trumann, Arkansas) renamed to Special routes of U.S. Route 63.
- U.S. Route 641 Business (Murray, Kentucky) renamed to U.S. Route 641.
- U.S. Route 641 Spur (Benton, Kentucky) renamed to U.S. Route 641.
- U.S. Route 641 Truck (Benton, Kentucky) renamed to U.S. Route 641.
- U.S. Route 641 in Indiana renamed to U.S. Route 641.
- U.S. Route 641 in Kentucky renamed to U.S. Route 641.
- U.S. Route 641 in Tennessee renamed to U.S. Route 641.
- U.S. Route 64A (Bat Cave–Morganton, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Brevard, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Columbia, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Franklinville-Ramseur, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Rocky Mount, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Siler City, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Statesville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64A (Williamston, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64B (Alma, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Bat Cave–Morganton, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Brevard, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Columbia, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Franklinville–Ramseur, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Princeville–Williamston, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Rocky Mount, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Rocky Mount–Tarboro, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Siler City, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Spring Hope, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Statesville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Alternate (Williamston, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Alma, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Asheboro, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Augusta, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Brevard, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Brevard, North Carolina 1960–1980) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Columbia, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Crawfordsville, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Earle, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Enid, Oklahoma) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Farmington, New Mexico) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Hayesville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Jamesville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Lawrenceburg, Tennessee) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Morganton, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Muskogee, Oklahoma) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Nashville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Parkin, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Patterson–McCrory, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Pittsboro, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Raleigh, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Raleigh–Zebulon, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Rocky Mount, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Rosman, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Selmer, Tennessee) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Statesville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Tarboro–Princeville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Vilonia, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Whiteville, Tennessee) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Williamston, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Business (Wynne, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Bypass (Asheboro, North Carolina) renamed to U.S. Route 64 in North Carolina.
- U.S. Route 64 Bypass (Cleveland, Tennessee) renamed to APD-40.
- U.S. Route 64 Bypass (Fayetteville, Tennessee) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Bypass (Manns Harbor–Manteo, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Spur (Wynne, Arkansas) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Truck (Franklin–Hendersonville, North Carolina) renamed to Special routes of U.S. Route 64.
- U.S. Route 64 Truck (Savannah, Tennessee) renamed to Special routes of U.S. Route 64.
- U.S. Route 650 renamed to U.S. Route 285.
- U.S. Route 65B (Western Grove, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65S (Pine Bluff, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 (Mississippi-Louisiana) renamed to U.S. Route 65.
- U.S. Route 65 Business (Carrollton, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Clinton, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Conway, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Harrison, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Marshall, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Ozark, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Pine Bluff, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Point Lookout–Branson, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Springfield, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Trenton, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Business (Western Grove, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Bypass (Baton Rouge, Louisiana) renamed to U.S. Route 65 in Louisiana.
- U.S. Route 65 Bypass (Springfield, Missouri) renamed to Special routes of U.S. Route 65.
- U.S. Route 65 Spur (Pine Bluff, Arkansas) renamed to Special routes of U.S. Route 65.
- U.S. Route 666 renamed to U.S. Route 491.
- U.S. Route 666 in Arizona renamed to U.S. Route 191 in Arizona.
- U.S. Route 666 in Colorado renamed to U.S. Route 491.
- U.S. Route 666 in New Mexico renamed to U.S. Route 491.
- U.S. Route 666 in Utah renamed to U.S. Route 491.
- U.S. Route 66 Business (Pacific, Missouri) renamed to Business routes of Interstate 44.
- U.S. Route 66 City (St. Louis, Missouri) renamed to Special routes of U.S. Route 66.
- U.S. Route 66 Spur (Fort Leonard Wood, Missouri) renamed to Business routes of Interstate 44.
- U.S. Route 67B (Reyno, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67E (Arkadelphia–Donaldson, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67E (Little Rock, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67E (Morning Sun–Judsonia, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67W (Arkadelphia–Donaldson, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67W (Little Rock, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67W (Morning Sun–Judsonia, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Alternate (Illinois) renamed to Illinois Route 267.
- U.S. Route 67 Business renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Alvarado, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Beebe, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Biggers, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Cleburne, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Datto, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Dublin, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Fredericktown, Missouri) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Greenville, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Hoxie–Walnut Ridge, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Jacksonville, Illinois) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Leadington–Park Hills, Missouri) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Midlothian, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Poplar Bluff, Missouri) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Presidio, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Reyno, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Roseville, Illinois) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (San Angelo, Texas)(east) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (San Angelo, Texas)(west) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Searcy, Arkansas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Business (Sulphur Springs, Texas) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Bypass (St. Louis, Missouri) renamed to Special routes of U.S. Route 67.
- U.S. Route 67 Connector (Walnut Ridge, Arkansas) renamed to Special routes of U.S. Route 67.
- Draft:U.S. Route 67 in Illinois renamed to U.S. Route 67 in Illinois.
- U.S. Route 68 Alternate (Fairview, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Auburn, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Bowling Green, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Cadiz, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Elkton, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Glasgow, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Maysville, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Paris, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Business (Russellville, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Bypass (Hopkinsville, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Truck (Glasgow, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 68 Truck (Hopkinsville, Kentucky) renamed to Special routes of U.S. Route 68.
- U.S. Route 69 Alternate (Oklahoma–Kansas) renamed to U.S. Route 69.
- U.S. Route 6A renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Coventry–Windham, Connecticut) renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Danielson, Connecticut) renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Newtown–Southbury, Connecticut) renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Plymouth–Hartford, Connecticut) renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Rhode Island) renamed to Special routes of U.S. Route 6.
- U.S. Route 6A (Woodbury–Willimantic, Connecticut) renamed to Special routes of U.S. Route 6.
- U.S. Route 6N (Pennsylvania) renamed to U.S. Route 6N.
- U.S. Route 6N (Pennsylvania 1931–1935) renamed to U.S. Route 6N.
- U.S. Route 6 Alternate (Cortlandt, New York) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Alternate (Eastern Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Alternate (Ohio) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Alternate (Providence, Rhode Island) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Alternate (Western Greater Cleveland, Ohio) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Hastings, Nebraska) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Helper, Utah) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Lansing, Illinois–Lake Station, Indiana) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Napoleon, Ohio) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Price, Utah) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Scituate, Rhode Island) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Scranton, Pennsylvania) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Tunkhannock, Pennsylvania) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Business (Warren, Pennsylvania) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Bypass (Bourne, Massachusetts) renamed to Sandwich Road.
- U.S. Route 6 Bypass (Massachusetts) renamed to Special routes of U.S. Route 6.
- U.S. Route 6 Truck (Highlands, New York) renamed to Special routes of U.S. Route 6.
- U.S. Route 701 Alternate (Clinton, North Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 Business (Mount Pleasant, South Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 Business (Tabor City, North Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 Truck (Conway, South Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 Truck 1 (Conway, South Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 Truck 2 (Conway, South Carolina) renamed to Special routes of U.S. Route 701.
- U.S. Route 701 in North Carolina renamed to U.S. Route 701.
- U.S. Route 701 in South Carolina renamed to U.S. Route 701.
- U.S. Route 70A (Brownsville-Huntingdon, Tennessee) renamed to U.S. Route 70A (Tennessee).
- U.S. Route 70A (Durham, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Durham-Raleigh, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Goldsboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Greensboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Greensboro-High Point, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Hickory, North Carolina 1946-1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Hickory, North Carolina 1948-1957) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (High Point, North Carolina 1934-1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (High Point, North Carolina 1948-1957) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (High Point–Greensboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Hillsborough, North Carolina 1942-1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Hillsborough, North Carolina 1948-1960) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Kinston, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Lexington, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Morganton, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Salisbury, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A (Smithfield, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70A Bypass (Humboldt, Tennessee) renamed to U.S. Route 70A (Tennessee).
- U.S. Route 70A in Oklahoma renamed to U.S. Route 70 in Oklahoma.
- U.S. Route 70A in Pine Level, North Carolina renamed to Special routes of U.S. Route 70.
- U.S. Route 70A in Tennessee renamed to U.S. Route 70A (Tennessee).
- U.S. Route 70N (Oklahoma) renamed to U.S. Route 70 in Oklahoma.
- U.S. Route 70 Alternate (Durham, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Durham–Raleigh, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Goldsboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Greensboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (High Point, North Carolina 1934–1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (High Point, North Carolina 1948–1957) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (High Point–Greensboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Hildebran–Conover, North Carolina 1946-1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Hildebran–Conover, North Carolina 1948–1957) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Hillsborough, North Carolina 1942–1948) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Hillsborough, North Carolina 1948–1960) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Kinston, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Lexington, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Morganton, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Pine Level, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Salisbury, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Alternate (Smithfield, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Alamogordo, New Mexico) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Beaufort, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Camden, Tennessee) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Clayton–Smithfield, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (De Queen, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Dickson, Tennessee) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Durham, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Garner, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Glenwood, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Goldsboro, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Hillsborough, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Hot Springs, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Hugo, Oklahoma) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Huntingdon, Tennessee) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Kinston, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Lebanon, Tennessee) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Lexington, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Little Rock, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Marshall, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Morganton, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (New Bern, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Pomona, California) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Business (Thomasville, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Bypass (Durant, Oklahoma) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Bypass (Idabel, Oklahoma) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Bypass (Selma, North Carolina) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 City (Benton, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Temporary (Lockesburg–Kirby, Arkansas) renamed to Special routes of U.S. Route 70.
- U.S. Route 70 Truck (Roswell, New Mexico) renamed to U.S. Route 70 in New Mexico.
- U.S. Route 711 renamed to U.S. Route 220.
- U.S. Route 71B (Fort Smith, Arkansas) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Alternate (Joplin, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Alexandria, Louisiana) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Butler, Missouri) renamed to Business routes of Interstate 49.
- U.S. Route 71 Business (Butler–Passaic, Missouri) renamed to Business routes of Interstate 49.
- U.S. Route 71 Business (Clarinda, Iowa) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Fort Smith, Arkansas) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Joplin, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Maryville, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Neosho, Missouri) renamed to Business routes of Interstate 49.
- U.S. Route 71 Business (Nevada, Missouri) renamed to Business routes of Interstate 49.
- U.S. Route 71 Business (Northwest Arkansas) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Pineville–Anderson, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (St. Joseph, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Storm Lake, Iowa) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Tipton Ford–Carthage, Missouri) renamed to Business routes of Interstate 49.
- U.S. Route 71 Business (Waldron, Arkansas) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Business (Willmar, Minnesota) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Bypass (Alexandria, Louisiana) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Bypass (Kansas City, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Bypass (Platte City, Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 Temporary (Arkansas–Missouri) renamed to Special routes of U.S. Route 71.
- U.S. Route 71 in Iowa renamed to U.S. Route 71.
- U.S. Route 72 Business (Athens, Alabama) renamed to U.S. Route 72.
- U.S. Route 730 Spur (Wallula, Washington) renamed to U.S. Route 730.
- U.S. Route 730 Spur (Washington) renamed to U.S. Route 730.
- U.S. Route 73E renamed to U.S. Route 73.
- U.S. Route 73E (Kansas) renamed to U.S. Route 73.
- U.S. Route 73E (Nebraska) renamed to U.S. Route 73.
- U.S. Route 73W renamed to U.S. Route 73.
- U.S. Route 73W (Kansas) renamed to U.S. Route 73.
- U.S. Route 73W (Nebraska) renamed to U.S. Route 73.
- U.S. Route 74 Alternate (Asheville–Forest City) renamed to U.S. Route 74 Alternate (Asheville–Forest City, North Carolina).
- U.S. Route 74 Alternate (Bessemer City, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Leland, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Maxton–Lumberton, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Monroe, North Carolina 1949–1952) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Monroe, North Carolina 1952–1954) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Rockingham, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Rutherfordton, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Shelby, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Alternate (Wrightsville Beach, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Chadbourn–Whiteville, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Kings Mountain, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Laurinburg–Maxton, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Rockingham–Hamlet, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Rutherfordton–Forest City, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Business (Shelby, North Carolina) renamed to Special routes of U.S. Route 74.
- U.S. Route 74 Bypass (Monroe, North Carolina) renamed to Monroe Expressway.
- U.S. Route 74 Bypass (Shelby, North Carolina) renamed to Shelby Bypass.
- U.S. Route 74 Temporary (Chadbourn, North Carolina) renamed to U.S. Route 76 in North Carolina.
- U.S. Route 75 Alternate renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Alternate (Altoona, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Alternate (North Topeka–Hoyt, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Alternate (Wakarusa–North Topeka, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Altoona, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Henryetta, Oklahoma) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Houston, Texas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Le Mars, Iowa) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Nebraska City, Nebraska) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Sherman, Texas) renamed to Texas State Highway 91.
- U.S. Route 75 Business (Sioux City, Iowa) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Business (Topeka, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Bypass (Topeka, Kansas) renamed to Special routes of U.S. Route 75.
- U.S. Route 75 Temporary (Galveston–Houston, Texas) renamed to Special routes of U.S. Route 75.
- U.S. Route 76 Business (Chadbourn–Whiteville, North Carolina) renamed to U.S. Route 76 in North Carolina.
- U.S. Route 76 Business (Laurens, South Carolina) renamed to U.S. Route 76 in South Carolina.
- U.S. Route 76 Business (Newberry, South Carolina) renamed to U.S. Route 76 in South Carolina.
- U.S. Route 76 Business (Seneca, South Carolina) renamed to U.S. Route 76 in South Carolina.
- U.S. Route 76 Business (Sumter, South Carolina) renamed to U.S. Route 76 in South Carolina.
- U.S. Route 76 Connector (Columbia, South Carolina) renamed to Special routes of U.S. Route 76.
- U.S. Route 76 Connector (Florence, South Carolina) renamed to Special routes of U.S. Route 76.
- U.S. Route 76 Temporary (Chadbourn, North Carolina) renamed to U.S. Route 76 in North Carolina.
- U.S. Route 76 Truck (Ringgold, Georgia) renamed to U.S. Route 76 in Georgia.
- U.S. Route 77 (Minnesota-South Dakota) renamed to U.S. Route 77.
- U.S. Route 77 Alternate Business (Yoakum, Texas) renamed to U.S. Route 77 Alternate.
- U.S. Route 789 renamed to Wyoming Highway 789.
- U.S. Route 78N renamed to Special routes of U.S. Route 78.
- U.S. Route 78S renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Alternate (Alabama–Georgia) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Alternate (Birmingham–Irondale, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Alternate (Carbon Hill–Jasper, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Alternate (Hamilton–Graysville, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Anniston, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Athens, Georgia) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Blackville, South Carolina) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Hickory Flat, Mississippi) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Red Banks, Mississippi) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Business (Washington, Georgia) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Connector (Bamberg County, South Carolina) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Connector (Blackville, South Carolina) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Truck (Aiken, South Carolina) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Truck (Birmingham, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 78 Truck (Leeds, Alabama) renamed to Special routes of U.S. Route 78.
- U.S. Route 79B (Bearden, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79B (Fordyce, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79C (McNeil, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Altheimer, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Bearden, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Camden, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Carthage, Texas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Clarendon, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Fordyce, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Henderson, Texas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Magnolia, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Pine Bluff, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Stuttgart, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Taylor, Texas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Business (Thornton, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Bypass (Homer, Louisiana) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 Bypass (Humboldt, Tennessee) renamed to Special routes of U.S. Route 79.
- U.S. Route 79 City (McNeil, Arkansas) renamed to Special routes of U.S. Route 79.
- U.S. Route 7 Alternate (Burlington, Vermont) renamed to U.S. Route 7 in Vermont.
- U.S. Route 80N renamed to U.S. Route 80.
- U.S. Route 80 (California-Arizona-New Mexico) renamed to U.S. Route 80.
- U.S. Route 80 Alternate (Abilene–Weatherford, Texas) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Alternate (El Paso, Texas) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Alternate (Phoenix, Arizona 1930s–1940s) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Alternate (Phoenix, Arizona 1930s–1960s) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Business (Abilene, Texas) renamed to Business routes of Interstate 20 in Texas.
- U.S. Route 80 Business (Big Spring, Texas) renamed to Business routes of Interstate 20 in Texas.
- U.S. Route 80 Business (Colorado City, Texas) renamed to Business routes of Interstate 20 in Texas.
- U.S. Route 80 Business (Odessa–Midland, Texas) renamed to Business routes of Interstate 20 in Texas.
- U.S. Route 80 Business (Selma, Alabama) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Business (Sierra Blanca, Texas) renamed to Business routes of Interstate 10.
- U.S. Route 80 Business (Sweetwater, Texas) renamed to Business routes of Interstate 20 in Texas.
- U.S. Route 80 Business (Van Horn, Texas) renamed to Business routes of Interstate 10.
- U.S. Route 80 Business (Yuma, Arizona) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Truck (Arcadia, Louisiana) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Truck (Gibsland, Louisiana) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Truck (Minden, Louisiana) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Truck (Selma, Alabama) renamed to Special routes of U.S. Route 80.
- U.S. Route 80 Truck (Tombstone, Arizona) renamed to Special routes of U.S. Route 80.
- U.S. Route 81 Business (Alvord, Texas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Decatur, Texas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Fargo, North Dakota) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Grand Forks, North Dakota) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Lindsborg, Kansas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (McPherson, Kansas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (McPherson County, Kansas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Rhome, Texas) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (Rush Springs, Oklahoma) renamed to Special routes of U.S. Route 81.
- U.S. Route 81 Business (San Antonio, Texas) renamed to Special routes of U.S. Route 81.
- U.S. Route 82B (Magnolia, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82B (Montrose, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82S (Felsenthal National Wildlife Refuge, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82T (Stamps, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Alternate (Montgomery–Prattville, Alabama) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Albany, Georgia) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Avery, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Clarksville, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (El Dorado, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Holliday, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Magnolia, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Montgomery, Alabama) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Montrose, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Paris, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Wichita Falls, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Business (Wolfforth, Texas) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Bypass (Montgomery, Alabama 1961–1965) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Bypass (Montgomery, Alabama 1965–1975) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Bypass (Tuscaloosa, Alabama) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 City (Montgomery, Alabama) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Spur (Felsenthal National Wildlife Refuge) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Truck (Montgomery, Alabama) renamed to Special routes of U.S. Route 82.
- U.S. Route 82 Truck (Stamps, Arkansas) renamed to Special routes of U.S. Route 82.
- U.S. Route 83 Business (Abilene, Texas) renamed to Business routes of U.S. Route 83 in Texas.
- U.S. Route 83 Business (Garden City, Kansas) renamed to U.S. Route 83 in Kansas.
- U.S. Route 83 Business (Laredo, Texas) renamed to Business routes of U.S. Route 83 in Texas.
- U.S. Route 83 Business (San Ygnacio, Texas) renamed to Business routes of U.S. Route 83 in Texas.
- U.S. Route 84 Business (Bainbridge, Georgia) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Dothan, Alabama) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Enterprise, Alabama) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Hermleigh, Texas) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Natchez, Mississippi) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Roscoe, Texas) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Slaton, Texas) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Snyder, Texas) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Teague, Texas) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Business (Thomasville, Georgia) renamed to Special routes of U.S. Route 84.
- U.S. Route 84 Truck (Enterprise, Alabama) renamed to Special routes of U.S. Route 84.
- U.S. Route 85 Alternate (Albuquerque, New Mexico) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Alternate (Anthony–Las Cruces, New Mexico) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (Alexander, North Dakota) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (El Paso, Texas) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (Greeley, Colorado) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (Platteville, Colorado) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (Watford City, North Dakota) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Business (Williston, North Dakota) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Bypass (Fountain–Colorado Springs, Colorado) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Bypass (Santa Fe, New Mexico) renamed to Special routes of U.S. Route 85.
- U.S. Route 85 Truck (Lead–Deadwood, South Dakota) renamed to Special routes of U.S. Route 85.
- U.S. Route 86 renamed to U.S. Route 84.
- U.S. Route 87E renamed to U.S. Route 87.
- U.S. Route 87E (Arizona) renamed to Unconstructed state routes in Arizona.
- U.S. Route 87W (Arizona) renamed to Unconstructed state routes in Arizona.
- U.S. Route 87 Business (Big Spring, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Buffalo, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 87 Business (Casper, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 87 Business (Cheyenne, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 87 Business (Dalhart, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Douglas, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 87 Business (Lamesa, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Lubbock, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (New Deal, Texas) renamed to List of state highway loops in Texas (400–499).
- U.S. Route 87 Business (O'Donnell, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Plainview, Texas) renamed to Interstate 27 Business (Plainview, Texas).
- U.S. Route 87 Business (San Antonio, Texas) renamed to Texas State Highway Spur 345.
- U.S. Route 87 Business (Sheridan, Wyoming) renamed to Business routes of Interstate 90.
- U.S. Route 87 Business (Stockdale, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Tahoka, Texas) renamed to Special routes of U.S. Route 87 in Texas.
- U.S. Route 87 Business (Wheatland, Wyoming) renamed to Business routes of Interstate 25.
- U.S. Route 87 Business (Woodrow, Texas) renamed to List of state highway loops in Texas (400–499).
- U.S. Route 87 Bypass (Great Falls, Montana) renamed to U.S. Route 87 in Montana.
- U.S. Route 87 Bypass (Lewistown, Montana) renamed to U.S. Route 87 in Montana.
- U.S. Route 87 in Arizona renamed to Unconstructed state routes in Arizona.
- U.S. Route 89T renamed to U.S. Route 89 in Arizona.
- U.S. Route 8 Business (Rhinelander, Wisconsin) renamed to U.S. Route 8.
- U.S. Route 90-Z renamed to U.S. Route 90 Business (New Orleans, Louisiana).
- U.S. Route 90 Alternate (Jacksonville, Florida) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Alternate (Pensacola, Florida) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Alternate (Tallahassee, Florida) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Business (Houston–Barrett, Texas) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Business (Lake Charles, Louisiana) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Business (Morgan City, Louisiana) renamed to Special routes of U.S. Route 90.
- U.S. Route 90 Business (Orange, Texas) renamed to Special routes of U.S. Route 90.
- U.S. Route 91 (Montana) renamed to U.S. Route 91.
- U.S. Route 91 Alternate (Las Vegas, Nevada) renamed to Nevada State Route 604.
- U.S. Route 91 in Nevada renamed to Interstate 15 in Nevada.
- U.S. Route 92 Alternate (Lakeland, Florida) renamed to U.S. Route 92.
- U.S. Route 92 Business (Lakeland, Florida) renamed to U.S. Route 92.
- U.S. Route 92 Truck (Kissimmee, Florida) renamed to U.S. Route 92.
- U.S. Route 92 Truck (Maitland, Florida) renamed to U.S. Route 92.
- U.S. Route 92 Truck (Orlando, Florida) renamed to U.S. Route 92.
- U.S. Route 93A in Arizona renamed to Unconstructed state routes in Arizona.
- U.S. Route 93T renamed to Unconstructed state routes in Arizona.
- U.S. Route 93 Alternate (Shoshone–Challis, Idaho) renamed to U.S. Route 93.
- U.S. Route 93 Spur (Kingman, Arizona) renamed to U.S. Route 93 in Arizona.
- U.S. Route 94 renamed to Tamiami Trail.
- U.S. Route 95 Alternate renamed to Special routes of U.S. Route 95.
- U.S. Route 95 Alternate (St. Maries, Idaho) renamed to Special routes of U.S. Route 95.
- U.S. Route 95 Business (Las Vegas, Nevada) renamed to Nevada State Route 599.
- U.S. Route 95 Spur (Lewiston, Idaho) renamed to U.S. Route 195.
- U.S. Route 95 Spur (Payette, Idaho) renamed to Special routes of U.S. Route 95.
- U.S. Route 95 Spur (Weiser, Idaho) renamed to Special routes of U.S. Route 95.
- U.S. Route 95 Truck (San Luis, Arizona) renamed to Special routes of U.S. Route 95.
- U.S. Route 96 (1926) renamed to U.S. Route 59 in Texas.
- U.S. Route 96 Business (Buna, Texas) renamed to U.S. Route 96.
- U.S. Route 96 Business (Silsbee, Texas) renamed to U.S. Route 96.
- U.S. Route 97 Alternate (Chelan, Washington) renamed to U.S. Route 97 Alternate.
- U.S. Route 97 Business (Bend, Oregon) renamed to U.S. Route 97 in Oregon.
- U.S. Route 97 Business (Klamath Falls, Oregon) renamed to U.S. Route 97 in Oregon.
- U.S. Route 97 Business (Okanogan–Omak, Washington) renamed to Washington State Route 215.
- U.S. Route 97 Business (Redmond, Oregon) renamed to U.S. Route 97 in Oregon.
- U.S. Route 97 Spur (Orondo, Washington) renamed to U.S. Route 97 in Washington.
- U.S. Route 98 Alternate (Alabama) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Alternate (Panama City Beach, Florida) renamed to Florida State Road 30.
- U.S. Route 98 Business (Bartow, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Business (Dade City, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Business (Lakeland, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Business (Natchez, Mississippi) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Business (Panama City, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Business (Pensacola, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Bypass (Panama City Beach, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Toll (Pensacola, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Truck (Brooksville, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 98 Truck (Dade City, Florida) renamed to Special routes of U.S. Route 98.
- U.S. Route 99E (Oregon) renamed to Oregon Route 99E.
- U.S. Route 99T renamed to Washington State Route 599.
- U.S. Route 99W (Oregon) renamed to Oregon Route 99W.
- U.S. Route 99W (central California) renamed to U.S. Route 99 in California.
- U.S. Route 99 Alternate renamed to U.S. Route 99.
- U.S. Route 99 Alternate (Bellingham–Lynden, Washington) renamed to Washington State Route 539.
- U.S. Route 99 Alternate (Burlington–Bellingham, Washington) renamed to Washington State Route 11.
- U.S. Route 9E renamed to U.S. Route 9 in New York.
- U.S. Route 9 Alternate (Toms River, New Jersey) renamed to Special routes of U.S. Route 9.
- U.S. Route 9 Business renamed to Special routes of U.S. Route 9.
- U.S. Route 9 Business (Lewes, Delaware) renamed to Special routes of U.S. Route 9.
- U.S. Route 9 Temporary (Beesley's Point, New Jersey) renamed to Special routes of U.S. Route 9.
- U.S. Route 9 Truck renamed to Special routes of U.S. Route 9.
- U.S. Route 9 Truck (Georgetown, Delaware) renamed to Special routes of U.S. Route 9.
- U.S. Routes 98-301 Truck (Dade City, Florida) renamed to Special routes of U.S. Route 98.
- United States Numbered Highways renamed to United States Numbered Highway System.
- Washington State Route 95 renamed to U.S. Route 95.
- Wisconsin Dells Parkway renamed to U.S. Route 12 in Wisconsin.
Removed
[edit]- File:014 12.24.100.136 wrong way concurrency.jpg (talk) removed.
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- File:2014-05-21 13 50 19 Sign on Alternate U.S. Route 93 northbound just north of U.S. Route 93 in Lages Junction, Nevada.JPG (talk) removed.
- File:2016-10-02 12 21 25 View south along U.S. Route 1 (Rhode Island Avenue NE) at V Street NE in Washington, D.C..jpg (talk) removed.
- File:2017-07-12 11 23 10 View south along U.S. Route 13 (Chesapeake Bay Bridge-Tunnel) crossing the North Channel of the Chesapeake Bay in Northampton County, Virginia.jpg (talk) removed.
- File:2019-07-14 13 12 11 View west along Interstate 68 and U.S. Route 40 (National Freeway) from the Victor Cushwa Memorial Bridge as it passes through the Sideling Hill Road Cut in Forest Park, Washington County, Maryland.jpg (talk) removed.
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