User talk:94rain/Archive 3

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My Wiki Article

I added in my 2nd and 3rd hand sources for my Dideye Dito wiki article that you declined. thing is. i created him. its my own comic series ok. — Preceding unsigned comment added by ThatCheeseGuy (talk • contribs) 04:30, 16 September 2019 (UTC)

ThatCheeseGuy, Wikipedia is not a publisher of original thought or web hosting service. Please see WP:NOT 94rain ^Talk 04:31, 17 September 2019 (UTC)

Request on 11:04:28, 18 October 2019 for assistance on AfC submission by Rahulogies

• Rahulogies (talk · contribs)
  • Draft:Codesler (edit | talk | history | links | watch | logs)

Thankyou! For your response my friend. Codesler is a company and the google knowledge graph is also live, you can check it. All the information are true. Help me to how my page is live on wikipedia?

Rahulogies (talk) 11:04, 18 October 2019 (UTC)

Rahulogies, This submission lacks independent, reliable, published sources, not just to materials produced by the company itself. This is important so that the article can meet Wikipedia's verifiability policy and the notability of the subject can be established. Otherwise it is not worthy of inclusion in Wikipedia. 94rain ^Talk 11:07, 18 October 2019 (UTC)

Rahulogies, You can find sources from media, books or journals. Find sources: Google (books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL If sources cannot be found, I am sorry, it is not suitable for a stand-alone Wikipedia article. Otherwise, you can consider alternatives to publish this article. 94rain ^Talk 11:22, 18 October 2019 (UTC)

Edward Anders entry

Thanks, 94rain, for moving this forward. I see it's tagged for now as a Class C entry, and I'd be glad to do some more work to make it better. A bit of guidance would be welcome.

The most visible path to me would be a fuller recap of the subject's scientific work, with links to original papers in Nature, Science, etc., as well as relevant books. But if there are other gaps that I should attend to as well, just let me know. Thanks! GCA10 (talk) 16:04, 20 October 2019 (UTC)

We gots similar username

--94drought (talk) 07:00, 23 October 2019 (UTC)

Linda Seger

https://en.wikipedia.org/wiki/Linda_Seger

She may be a living person, but she's also a living scam, claiming to work in Hollywood, while never setting foot there.

She is a fraudster, who claims to help Hollywood movies with their scripts, while in reality all her credits are for reading scripts of Indie and foreign movies.

Sources cited to claim her legitimacy:

IMDB: written herself with IMDB Pro. scriptmag.com: it's just a blog of different people, the Script Magazine is long dead. — Preceding unsigned comment added by 31.200.239.202 (talk) 12:55, 13 December 2019 (UTC)

I've nominated that article for deletion. 94rain ^Talk 05:37, 14 December 2019 (UTC)

Merry Christmas!

	Merry Christmas and a Prosperous 2020!
	Hope you enjoy the Christmas eve with the ones you love and step into the new year with lots of happiness and good health. Wishing you a Merry Christmas and a very Happy New Year!CAPTAIN RAJU(T) 21:02, 21 December 2019 (UTC)

Patrolling of articles

Hello! Colleague, could you please to patrol this and this articles? Thank you. — Green Zero обг 21:54, 23 December 2019 (UTC)

Merry Christmas!

Hello 94rain: Enjoy the holiday season, and thanks for your work to maintain, improve and expand Wikipedia. Cheers, Everedux ^(talk) 19:34, 25 December 2019 (UTC)

Spread the WikiLove; use {{subst:Season's Greetings1}} to send this message

Some important informations from TonyBallioni

TonyBallioni provide some valuable advice to Light-n-Dorkiness-2k:

https://meta.wikimedia.org/wiki/User_talk:LightandDark2000#Arturo

This is a good advice because you are even more severe Goody2Shoes. Did T.Baloney contacted you via IRC? Anyway, you might have happier 2020 if follow T.Baloney's advice.

--96.78.176.205 (talk) 04:41, 1 January 2020 (UTC)

Well, if you stop wasting time creating accounts and messing around, we all can have a more meaningful new year. --94rain ^Talk 05:12, 1 January 2020 (UTC)

Happy New Year 94rain!

Happy New Year!

Hello 94rain:
Thanks for all of your contributions to improve the encyclopedia for Wikipedia's readers, and have a happy and enjoyable New Year! Cheers, Donner60 (talk) 05:30, 28 December 2019 (UTC)

Send New Year cheer by adding {{subst:Happy New Year fireworks (static)}} to user talk pages with a friendly message.

I would also like to wish you a Happy New Year and inquire if you made a same-named account on DP.   — Jeff G. ツ 18:24, 3 January 2020 (UTC)

Jeff G., yeah, that's me. Happy new year! -- 94rain ^Talk 04:36, 4 January 2020 (UTC)

Thanks!   — Jeff G. ツ 13:22, 4 January 2020 (UTC)

Regarding my article on Goshin Ishin-Ryu Karate Association

Thank you for your comment and advice. I will rewrite and submit it again. Any advice on the content? should I expand it. Have a good week ahead. — Preceding unsigned comment added by Teynmoli (talk • contribs) 12:59, 6 January 2020 (UTC)

Hi Teynmoli, sorry for the late reply. The major problem is about the sources. I'd suggest you find independent, reliable sources that provide significant coverage of the organization first. If such sources do not exist, it is not qualified for an article. If sources exist, you should then improve the article. The content should be written from a neutral point of view (See also Wikipedia:Manual of Style/Words to watch). Also, the founder section seems a bit irrelevant, as well as the image. Please consider simplify it or just remove it. Regards, 94rain ^Talk 12:03, 15 January 2020 (UTC)

Could you re-review Draft:Banpará?

Its been updated with references from Brazilian newspapers of record, along with some financial data and pictures. - Richevans69 (talk) 21:27, 21 January 2020 (UTC)

Request for review

Hi 94rain! I would like to request you for reviewing my draft page Epos 257 (https://en.wikipedia.org/wiki/Draft:Epos_257). I know that it was already reviewed and unfortunately declined, nevertheless I have rewritten it and I would like to ask you very much to check the article if at least a little possible...Thank you very much! Regards Jiří Jiří Gruber (talk) 12:35, 12 March 2020 (UTC)

Want to add my site's link

Hello sir,

I want to get back link from wiki for my affiliate blog. Let me know any way for that.

Thanks in advance. — Preceding unsigned comment added by Ervarun75 (talk • contribs) 15:54, 2 April 2020 (UTC)

A beer for you!

Enjoy your break. thanks for your comments and help. Kalyan1010 (talk) 16:15, 13 October 2021 (UTC)

thanks for the comments

https://www.thehindu.com/sci-tech/science/iisc-makes-two-potent-molecules-to-fight-tb/article18058311.ece https://www.deccanherald.com/content/564665/down-synthetic-route.html https://www.thehindu.com/sci-tech/health/iisc-team-unravels-how-vitamin-c-helps-kill-bacteria/article18191223.ece https://www.thebetterindia.com/97792/iisc-scientists-tb-health/ https://www.biovoicenews.com/sun-pharma-science-foundation-awards-indias-top-researchers/

Dr. Kirtimaan Syal's work has been cited in different newspapers from time to time. What else I can include for improvising the article. Can you suggest? thanks Kalyan1010 (talk) 16:45, 6 October 2021 (UTC)

>> all suggested changes have been incorporated. I request you to please re-review it. >> thanks Kalyan1010 (talk) 17:03, 10 October 2021 (UTC)

Hi Kalyan1010, sorry I've been a bit busy lately. Does Dr. Kirtimaan Syal satisfy any criteria mentioned in here (Wikipedia:Notability_(academics)#Criteria)? If not, are there any independent sources that introduce them in depth (not their work/publications)? If so, please specify and I'll take some time to review the article thoroughly within a week or so. Haven't looked through the revised article in detail yet, but I'd recommend not citing Dr. Kirtimaan Syal's publications directly (Wikipedia:No_original_research#Secondary). Thank you for your contributions. 94rain ^Talk 03:15, 13 October 2021 (UTC)

Thank you so much. Thanks to the interactions with several editors here who suggested WP:THREE, I made a list of independent references that I am copying here. See if there is more I can add to this article. These references independently describe his contribution to the field.

1. "ACS Omega (American Chemical Society). Antibiotic Resistance: Current Perspectives. by Anushya et al. (2017), 2 (10), 7400-7409. DOI: 10.1021/acsomega.7b01368. Paragraph, "With the aim of synthesizing more potent Rel inhibitors, Syal et al. modified guanosine at this C-2 position to synthesize acetylated and acetylated benzoylated derivatives of guanosine (Figure 5).(21) The acetylated benzoylated compound showed 50% inhibition at 40 μM and 75% inhibition at 100 μM. Addition of this compound led to inhibition of biofilm formation by M. tuberculosis. It also led to decreased long-term survival and cellular (p)ppGpp levels in Mycobacterium smegmatis. The compound was shown to be cell wall permeable in human lung epithelial cells and nontoxic to H460 cells. With information from the crystal structures of (p)ppGpp bound to its synthetases and effector proteins, more such analogues can be designed and synthesized chemically......Figure 5. Design of stringent response inhibitors. Relacin is a structural analogue of ppGpp. Guanosine was chemically modified to synthesize acetylated and acetylated benzoylated derivatives that inhibit Rel. Vitamin C is a natural analogue that resembles GDP in structure...... A recent study showed that vitamin C inhibits M. tuberculosis growth at high concentrations.(22) Syal et al. proposed vitamin C to be an inhibitor of stringent response and demonstrated its binding to Rel (Figure 5).(23) Addition of vitamin C inhibited (p)ppGpp synthesis by Rel in vitro as well as reduced in vivo (p)ppGpp levels and biofilm formation in M. smegmatis. Thus, this opens up opportunities to test vitamin C alone against bacterial infections....."".

2. Journal of Molecular Biology (Elsevier), Jacob et al. discusses Dr. Syal's work on Vitamin C. They say, "Interestingly, Syal and colleagues demonstrated that vitamin C inhibits (p)ppGpp synthesis inM. smegmatis, suggesting that vitamin C can exploit different mechanismsto prevent persister formation in mycobacteria. Although vitamin C and N-acetylcysteine could beused as adjunct therapy for TB as they are non-toxic and, in the case ofN-acetylcysteine, alreadyused in TB patients to help cope with TB drugtoxicity, the quantity required to achieve culture sterilization in vitro(mM range) may not be appli-cable in TB patients. Nevertheless, these findingssuggest that screening for compounds that increase M. tuberculosis respiration could provide a new path towards M. tuberculosis eradication....."

3. Ghosh et al. Small-Molecule Inhibition of Bacterial Biofilm. ACS Omega (American Chemical Society) 2020 5 (7), 3108-3115 DOI: 10.1021/acsomega.9b03695.

They discuss- "Both (p)ppGpp and c-di-GMP signaling pathways directly contribute to antimicrobial resistance development and hence can act as a promising therapeutic approach to reduce biofilm population, leading to increased susceptibility to standard drugs. The two second messenger synthetase enzymes, namely, Rel and DGC, are considered to be the most rational drug targets in order to reduce the intracellular concentration of (p)ppGpp and c-di-GMP, respectively. Syal and co-workers previously reported that vitamin C possesses structural similarity with Rel enzyme substrate guanosine diphosphate (GDP) and inhibits ppGpp biosynthesis by directly binding to Rel enzyme in M. smegmatis and subsequently prevents biofilm formation. Another study from the same group has shown that synthetic (p)ppGpp analogues directly inhibit ppGpp biosynthesis and can act as a potential biofilm inhibitor in mycobacteria. Figure 5 in this reference also comes from Dr. Syal’s work.…"

4. "Genes Robles CM, Coin F. Conducting the CTD orchestra. News and Views. Nature Chemical Biology (NPG) 2019 Feb;15(2):97-98". - It is a news and views article. The entire article discusses his group work. (Noncanonical CTD kinases regulate RNA polymerase II in a gene-class-specific manner. Nature Chemical Biology (NPG) 15, 123-131. Nemec, SAK, AA Tseng, K Syal, et al.)

Additionally, he has been felicitated by the Health Minister of India and Sun Pharma for his scientific contributions. There is a Syal method after his name which is being used by many. I included one citation on independent use as well. I guess there is enough ground for notability. Please share your thoughts. Kalyan1010 (talk) 05:45, 13 October 2021 (UTC)

Actually, if the sources are about their work, then these works will need to meet Wikipedia:Notability_(academics)#Specific_criteria_notes#1 to show the notability of the scholar. (academic-specific notability)
Alternatively, It'd be better to look for sources about themselves. (General notability) Are there sources about "he has been felicitated by the Health Minister of India and Sun Pharma for his scientific contributions."? --94rain ^Talk 06:51, 13 October 2021 (UTC)

Thank you so much for the comment and sharing interesting articles. I have gone through the notability aspect and in my opinion, he qualifies for it (considering point 1b in the specific criteria notes Wikipedia:Notability_(academics)#Specific_criteria_notes#1 and three independent resources WP:THREE). His work has been covered and discussed in detail in more than three peer-reviewed journals. Also, his Syal method and other research as discussed in the contribution section of the revised article qualify him as per point 4.

The coverage of his research in The Hindu, Times of India and Deccan Herald at different time points may add to the general notability aspect. Yes, I have added the citation to the felicitation by Health Minister and Sun Pharma in the revised article.

I think, he qualifies as per the academic notability criteria so the average general notability aspect should be ok. Kalyani Kalyan1010 (talk) 11:28, 13 October 2021 (UTC)

For the case of (1b) having developed a significant new concept, it is necessary to explicitly demonstrate, by a substantial number of references to academic publications. I am not seeing that at this point. For the general notability aspect, we are looking for coverage about themselves, not their research. 94rain ^Talk 23:51, 13 October 2021 (UTC)

I have already spent a lot of time on this article. As per the other editor, three independent reliable sources describing him and his work makes him notable. As far as number of references to publications are concerned, the number varies as per the field and research area. Besides, I do not know many scientists (Like him) in India who are being the topic of discussion in the peer reviewed journals. He designed sugars that are nutrient to humans and toxic to bacteria. He deciphered how VitaminC act as antibacterial. Earlier, Vit C was regarded as immunity booster and its role as antibacterial was largely underrepresented. He gave the molecular basis of antibacterial action of Vit C.

I described several Media citations along with the reference you were asking (felicitation by Health Minister of India). I don’t want to work more on it. If you let this article out, let others improvise it, then I may add to everyone’ efforts, else I don’t want to work individually on it. Kalyan1010 (talk) 05:11, 14 October 2021 (UTC)

I am sorry, but WP:No amount of editing can overcome a lack of notability. I appreciate your efforts. Let's consider WP:NACADEMIC#1d, are the journals where they published work selective? (low acceptance rate?) I requested for help from other reviewers in here --94rain ^Talk 01:14, 15 October 2021 (UTC)

Yes, the ACS journals are managed by American Chemical Society and Journal of Molecular Biology is headed by Editor-in-Chief from the Scripps Institute. Both are highly prestigious. On a lighter note, Harvard and Stanford hire researchers and faculty members based on publications in these journals. Kalyan1010 (talk) 04:56, 26 October 2021 (UTC)