TOX2
Appearance
TOX high mobility group box family member 2 | |||
---|---|---|---|
Identifiers | |||
Symbol | TOX2 | ||
Alt. symbols | C20orf100, GCX-1 | ||
NCBI gene | 84969 | ||
HGNC | 16095 | ||
OMIM | 611163 | ||
RefSeq | NM_001098796 | ||
UniProt | Q96NM4 | ||
Other data | |||
Locus | Chr. 20 q13.12 | ||
|
TOX high mobility group box family member 2, also known as TOX2, is a human gene.[1][2]
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX3, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[3]
References
[edit]- ^ "Entrez Gene: TOX high mobility group box family member 2".
- ^ Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K (May 2004). "Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells". Endocrinology. 145 (5): 2307–18. doi:10.1210/en.2003-1343. PMID 14764631. S2CID 25037508.
- ^ O'Flaherty E, Kaye J (April 2003). "TOX defines a conserved subfamily of HMG-box proteins". BMC Genomics. 4 (1): 13. doi:10.1186/1471-2164-4-13. PMC 155677. PMID 12697058.