Spasmolytic A29

Spasmolytic A29
Identifiers
CAS Number	29869-90-7 55011-89-7;
PubChem CID	122535;
ChemSpider	109252;
Chemical and physical data
Formula	C18H21N
Molar mass	251.373 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C=C(C1=CC=CC=C1)C2=CC=CC=C2)N(C)C;

A29^[1]^[2] is not used by itself but is co-administered with ketobemidone in a formulation, Ketogan. It is a regioisomer of amitriptyline with the bridge ethylene removed.

References

^ PETERSEN PV (1951). "Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21)". Acta Pharmacologica et Toxicologica. 7 (1): 51–64. doi:10.1111/j.1600-0773.1951.tb02849.x. PMID 14829296.
^ Ebert B, Thorkildsen C, Andersen S, Christrup LL, Hjeds H (September 1998). "Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists". Biochemical Pharmacology. 56 (5): 553–9. doi:10.1016/s0006-2952(98)00088-4. PMID 9783723.

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