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Orly Alter

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Orly Alter
Academic background
Alma mater
ThesisImpossibility of determining the quantum wavefunction of a single system and a fundamental limit to external force detection (1999)
Doctoral advisorYoshihisa Yamamoto (scientist)

Orly Alter is an Israeli-American physicist and research associate professor in the field of bioengineering and human genetics. She has published several papers about her research in genomic signal processing and bladder and brain cancers. She is a professor at the University of Utah[1].

Education and career

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Alter began attending school at Tel Aviv University in Israel and graduated in October 1989 magna cum laude with her bachelors of science in physics.[1] After receiving her undergraduate degree, she began pursuing her Ph.D. in applied physics at the Stanford University in California, USA. She completed her Ph.D. with a thesis on “Quantum Measurement of a Single System," under the mentorship of Yoshihisa Yamamoto in January of 1999[2] and then moved onto a postdoctoral fellowship working with genetics, remaining at Stanford. Alter moved to the University of Utah in 2010.[3]

Research

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Alter has one published book named Genomic Signal Processing: Discovery of Principles of Nature from Matrix and Tensor Modeling of Large-Scale Molecular Biological Data.[4] Alter's work on finding patterns in DNA finds predictors indicative of a woman's risk for ovarian cancer,[5] and she uses mathematical models to improve the outcomes for women with ovarian cancer.[6]

Awards and recognition

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In 2005 Alter was selected by the International Linear Algebra Society to give the Linear Algebra and its Applications Lecture.[7]

Selected publications

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  • Alter, Orly; Brown, Patrick O.; Botstein, David (29 August 2000). "Singular value decomposition for genome-wide expression data processing and modeling". Proceedings of the National Academy of Sciences. 97 (18): 10101–10106. Bibcode:2000PNAS...9710101A. doi:10.1073/pnas.97.18.10101. ISSN 0027-8424. PMC 27718. PMID 10963673.
  • Alter, Orly; Brown, Patrick O.; Botstein, David (18 March 2003). "Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms". Proceedings of the National Academy of Sciences. 100 (6): 3351–3356. Bibcode:2003PNAS..100.3351A. doi:10.1073/pnas.0530258100. ISSN 0027-8424. PMC 152296. PMID 12631705.
  • Omberg, Larsson; Golub, Gene H.; Alter, Orly (20 November 2007). "A tensor higher-order singular value decomposition for integrative analysis of DNA microarray data from different studies". Proceedings of the National Academy of Sciences. 104 (47): 18371–18376. Bibcode:2007PNAS..10418371O. doi:10.1073/pnas.0709146104. ISSN 0027-8424. PMC 2147680. PMID 18003902.
  • Alter, Orly. Genomic Signal Processing: Discovery of Principles of Nature from Matrix and Tensor Modeling. Wiley. ISBN 978-1-119-07837-1.

References

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  1. ^ a b "ORLY ALTER - Home - Faculty Profile - The University of Utah". faculty.utah.edu. Retrieved 13 March 2023.
  2. ^ Alter, Orly (1999). Impossibility of determining the quantum wavefunction of a single system and a fundamental limit to external force detection (Thesis).
  3. ^ "Orly Alter Joins the Scientific Computing and Imaging Institute as a USTAR Associate Professor of Bioengineering". www.sci.utah.edu. Retrieved 24 May 2024.
  4. ^ Alter, Orly. Genomic Signal Processing: Discovery of Principles of Nature from Matrix and Tensor Modeling. Wiley. ISBN 978-1119078371.
  5. ^ "Accuracy of Diagnosis, Prognosis". USA Today; Farmingdale. Vol. 144, no. 2849. February 2016. p. 8 – via Proquest.
  6. ^ "U. researchers' mathematical models could provide better ovarian cancer treatment, outcomes". The Salt Lake Tribune; Salt Lake City, Utah. 15 April 2015 – via Proquest.
  7. ^ "LAA-lecturers". International Linear Algebra Society. Retrieved 24 May 2024.
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