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LL-100 panel

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The LL-100 panel is a group of 100 human leukemia and lymphoma cell line,[1] can be used in model of biomedical research.[2]

Purpose

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LL-100 panel cell lines cover the full spectrum of human leukemia and lymphoma including T-cell, B-cell and myeloid malignancies.[1]

List of LL-100 cell lines

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Pre-B-ALL

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Cell line Sex Age Ref Cellosaurus
697 Male 12Y [3] CVCL_0079
KOPN-8 Female 3M [4] CVCL_1866
NALM-6 Male 19Y [5] CVCL_0092
REH Female 15Y [6] CVCL_1650
SEM Female 5Y [7] CVCL_0095

B-NHL: Burkitt/B-ALL

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Cell line Sex Age Ref Cellosaurus
BJAB [zh] Female 5Y [8] CVCL_5711
Daudi cell [zh] Male 16Y [9] CVCL_0008
Raji Male 11Y [10] CVCL_0511
RAMOS Male 3Y [11] CVCL_0597
VAL Female 50Y [12] CVCL_1819

B-NHL: CLL/PLL

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Cell line Sex Age Ref Cellosaurus
HG-3 Male 70Y [13] CVCL_Y547
JVM-3 Male 73Y [14] CVCL_1320
JVM-13 Male 60-69Y [15] CVCL_1318
MEC-1 Male 61Y [16] CVCL_1870
PGA-1 Male unspecified [17] CVCL_Y545

B-NHL: DLBCL ABC

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Cell line Sex Age Ref Cellosaurus
NU-DHL-1 Male 73Y [18] CVCL_1876
OCI-Ly3 Male 52Y [19] CVCL_8800
Ri-1 Female 57Y [20] CVCL_1885
U-2932 Female 29Y [21] CVCL_1896
U-2946 Male 52Y [22] CVCL_X503

B-NHL: DLBCL GC

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Cell line Sex Age Ref Cellosaurus
DoHH2 Male 60Y [23] CVCL_1179
OCI-Ly7 Male 48Y [19] CVCL_1881
OCI-Ly19 Female 27Y [24] CVCL_1878
SU-DHL-4 Male 38Y [25] CVCL_0539
SU-DHL-6 Male 43Y [25] CVCL_2206
WSU-DLCL2 Male 41Y [26] CVCL_1902

B-NHL: HCL

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Cell line Sex Age Ref Cellosaurus
BONNA-12 Male 46Y [27] CVCL_1090
Hair-M Male 86Y [28] CVCL_B401
HC-1 Male 56Y [29] CVCL_1243

B-NHL: MCL

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Cell line Sex Age Ref Cellosaurus
Granta-519 Female 58Y [30] CVCL_1818
JeKo-1 Female 78Y [31] CVCL_1865
JVM-2 Female 63Y [14] CVCL_1319
Mino Male 68Y [32] CVCL_1872
REC-1 Male 61Y [33] CVCL_1884

B-NHL: PEL

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Cell line Sex Age Ref Cellosaurus
BC-3 Male 85Y [34] CVCL_1080
BCBL-1 Male 40Y [35] CVCL_0165
CRO-AP2 Male 49Y [36] CVCL_1147
CRO-AP5 Male 35Y [37] CVCL_1148

B-NHL: PMBL

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Cell line Sex Age Ref Cellosaurus
U-2940 Female 18Y [38] CVCL_1897

Multiple myeloma/PCL

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Cell line Sex Age Ref Cellosaurus
KMS-12-BM Female 64Y [39] CVCL_1334
L-363 Female 36Y [40] CVCL_1357
LP-1 Female 56Y [41] CVCL_0012
OPM-2 Female 56Y [42] CVCL_1625
RPMI-8226 Male 61Y [43] CVCL_0014
U-266 Male 53Y [44] CVCL_0566

Hodgkin lymphoma

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Cell line Sex Age Ref Cellosaurus
HDLM-2 Male 74Y [45] CVCL_0009
KM-H2 Male 37Y [46] CVCL_1330
L-428 Female 37Y [45] CVCL_1361
L-1236 Male 34Y [47] CVCL_2096
SUP-HD1 Male 37Y [48] CVCL_2208

T-ALL/T-LL

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Cell line Sex Age Ref Cellosaurus
CCRF-CEM [zh] Female 3Y11M [49] CVCL_0207
DND-41 [zh] Male 13Y [50] CVCL_2022
HPB-ALL Male 14Y [51] CVCL_1820
Jurkat Male 14Y [52] CVCL_0065
MOLT-4 Male 19Y [53] CVCL_0013
RPMI-8402 Female 16Y [54] CVCL_1667

Mature T-malignancy

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Cell line Sex Age Ref Cellosaurus
DERL-7 Male 30Y [55] CVCL_2017
HH Male 61Y [56] CVCL_1280
MOTN-1 Female 65Y [57] CVCL_2127

NK malignancy

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Cell line Sex Age Ref Cellosaurus
KHYG-1 Female 45Y [58] CVCL_2976
NK-92 Male 50Y [59] CVCL_2142
YT Male 15Y [60] CVCL_1797

ALCL

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Cell line Sex Age Ref Cellosaurus
DEL Male 12Y [61] CVCL_1170
SR-786 Male 11Y [62] CVCL_1711
SU-DHL-1 Male 10Y [63] CVCL_0538
SUP-M2 Female 5Y [64] CVCL_2209

AML myelocytic

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Cell line Sex Age Ref Cellosaurus
EoL-1 [zh] Male 33Y [65] CVCL_0258
HL-60 Female 36Y [66] CVCL_0002
Kasumi-1 Male 7Y [67] CVCL_0589
KG-1 [zh] Male 59Y [68] CVCL_0374
NB4 Female 23Y [69] CVCL_0005
OCI-AML3 Male 57Y [70] CVCL_1844
SKNO-1 Male 22Y [71] CVCL_2196

AML monocytic

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Cell line Sex Age Ref Cellosaurus
ME-1 Male 40Y [72] CVCL_2110
MOLM-13 Male 20Y [73] CVCL_2119
Mono-Mac-6 Male 64Y [74] CVCL_1426
MUTZ-3 Male 29Y [75] CVCL_1433
THP-1 Male 1Y [76] CVCL_0006
U-937 Male 37Y [77] CVCL_0007

AML erythroid

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Cell line Sex Age Ref Cellosaurus
F-36P Male 68Y [78] CVCL_2037
HEL Male 30Y [79] CVCL_0001
OCI-M2 unspecified 56Y [80] CVCL_2150
TF-1 Male 35Y [81] CVCL_0559

AML megakaryocytic

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Cell line Sex Age Ref Cellosaurus
CMK Male 10M [82][83] CVCL_0216
ELF-153 Male 41Y [84] CVCL_2031
M-07e Female 6M [85] CVCL_2106
MEGAL Female unspecified [86] CVCL_1833
MKPL-1 Male 66Y [87] CVCL_2116
UT-7 Male 64Y [83] CVCL_2233

CML myeloid BC

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Cell line Sex Age Ref Cellosaurus
EM-2 Female 5Y [88] CVCL_1196
K-562 Female 53Y [89][90] CVCL_0004
KCL-22 Female 32Y [91] CVCL_2091
Ku812 Male 38Y [92] CVCL_0379
LAMA-84 Female 29Y [93] CVCL_0388
MOLM-20 Female 63Y [86] CVCL_2121

CML lymphoid BC

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Cell line Sex Age Ref Cellosaurus
BV-173 Male 45Y [94] CVCL_0181
CML-T1 Female 36Y [95] CVCL_1126
NALM-1 Female 3Y [96] CVCL_0091
TK-6 Male 30Y [97] CVCL_X907

MPN

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Cell line Sex Age Ref Cellosaurus
SET-2 Female 71Y [98] CVCL_2187

See also

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References

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  2. ^ Drexler, HG; Quentmeier, H (13 August 2020). "The LL-100 Cell Lines Panel: Tool for Molecular Leukemia-Lymphoma Research". International Journal of Molecular Sciences. 21 (16): 5800. doi:10.3390/ijms21165800. PMC 7461097. PMID 32823535.
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