Genetex
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GeneTex is a life science, biotechnology company that develops, licenses, and sells a product catalog of research reagents related to the study of the biomedical sciences. The company provides antibodies and proteins for use by academic and industry investigators involved in basic and translational research in biology and medicine.[1]
| Company type | Private |
|---|---|
| Industry | Biotechnology, Life Sciences |
| Founded | 1997 |
| Founders | Joel B. Baseman, Eva Y.-H. P. Lee, Wen-Hwa Lee, C. Kent Osborne |
| Headquarters | |
Areas served | International |
| Products | Research Antibodies, kits and assays for biological research |
Number of employees | 50-200 |
| Website | www |
In 2016, GeneTex together with antibody research companies Novus Biologicals, R&D Systems, and Atlas Antibodies joined the International Working Group on Antibody Validation (IWGAV) with the intention to help standardize best practices in antibody validation.[2][3]
Recombinant monoclonal antibody technology
[edit]GeneTex has incorporated recombinant monoclonal antibody technology into its product development platform. This technology has numerous well-documented advantages, with consistency of performance being of paramount significance. The protocol employed is a multi-parameter approach based on fluorescence-activated cell sorting (FACS) to isolate antigen-specific memory B cells from an immunized animal, with subsequent cloning of the antibody variable-region genes into an Immunoglobulin G (IgG) backbone and expression in mammalian cells. The entire development procedure can be completed in weeks.[4]
References
[edit]- ^ "About Us | GeneTex". www.genetex.com. Retrieved 2019-07-18.
- ^ "GeneTex Five Pillars of Antibody Validation".
- ^ Uhlen, Mathias; Bandrowski, Anita; Carr, Steven; Edwards, Aled; Ellenberg, Jan; Lundberg, Emma; Rimm, David L.; Rodriguez, Henry; Hiltke, Tara; Snyder, Michael; Yamamoto, Tadashi (October 2016). "A proposal for validation of antibodies". Nature Methods. 13 (10): 823–827. doi:10.1038/nmeth.3995. PMC 10335836. PMID 27595404. S2CID 34259132.
- ^ "Recombinant Antibodies | GeneTex". www.genetex.com. Retrieved 2020-10-30.