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File:Schematic representation of breast cancer metastatic study models.pdf

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English: The transgenic mice can be crossed with other transgenic mice generating tri transgenic or multiple transgenic mice. Crossbreeding with a reporter mice or inducible mice will generate multiple transgenes in the mammary gland as the promoter is mammary specific. Cells from new transgenic mice mammary glands can be transplanted in the cleared mammary fat pad or in lateral tail vein (in immunodeficient recipient mice) recipient to see the metastasis at ectopic sites. Mice have ten mammary glands and all of them can be harvested from transgenic mice to make single-cell suspension for metastases study assays
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Master's work

Previously published: Published on thesis at McGill university
Author FarhiaKabeer

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1 January 2013

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current19:19, 4 March 2015Thumbnail for version as of 19:19, 4 March 20151,650 × 1,275 (704 KB)Sjones008{{subst:Upload marker added by en.wp UW}} {{Information |Description = {{en|The tri transgenic mice can be bread with reporter mice or inducible mice to generate multiple transgenes in the mammary gland such that when the cells from mammary glands are...

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