Draft:Gut Microbiome and Mental Health
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The gut microbiome, a complex ecosystem of bacteria, viruses, fungi, protozoa, and archaea, plays a critical role in regulating numerous physiological processes, including metabolism, immune function, and maintaining gut integrity. Its influence extends to the gut-brain axis, a bidirectional communication network connecting the gastrointestinal system and the central nervous system via neural, endocrine, and immune pathways. Disruptions in the gut microbiota, known as dysbiosis, have been associated with psychiatric disorders such as depression, anxiety, bipolar disorder, and autism spectrum disorder, often mediated by increased inflammation, impaired gut barrier function, and altered neurotransmitter synthesis. This growing understanding brings to light the critical role the microbiota plays in mental health and its potential as a therapeutic target.