CD36 antigen
| CD36 family | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | CD36 | ||||||||
| Pfam | PF01130 | ||||||||
| InterPro | IPR002159 | ||||||||
| |||||||||
CD36 antigen is a transmembrane, highly glycosylated, glycoprotein expressed by monocytes, macrophages, platelets, microvascular endothelial cells and adipose tissues. CD36 recognises oxidized low density lipoprotein, long chain fatty acids, anionic phospholipids, collagen types I, IV and V, thrombospondin and Plasmodium falciparum infected erythrocytes.[1]
CD molecules are leucocyte antigens on cell surfaces. CD antigens nomenclature is updated at Protein Reviews On The Web (https://web.archive.org/web/20080920090434/http://mpr.nci.nih.gov/prow/).
Subfamilies
[edit]Human proteins containing this domain
[edit]References
[edit]- ^ Crombie R, Silverstein R (February 1998). "Lysosomal integral membrane protein II binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif". The Journal of Biological Chemistry. 273 (9): 4855–63. doi:10.1074/jbc.273.9.4855. PMID 9478926.
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