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Sim4Life
Developer(s)ZMT Zurich MedTech AG
Stable release
V8.0.1 / June 18, 2024; 6 months ago (2024-06-18)
TypeComputer-aided design
Websitewww.sim4life.swiss

Sim4Life (V8.x Web and Desktop) is a computational simulation platform developed by ZMT Zurich MedTech AG (ZMT) in Zurich, Switzerland, in partnership with the Foundation for Research on Information Technologies in Society (IT'IS), with funding from Innosuisse (formerly known as CTI),[1][2] a Swiss federal funding instrument. The Sim4Life platform is an extension of the SEMCAD X Matterhorn computer-aided-design-based simulation platform marketed by IT’IS partner Schmid and Partner Engineering AG (SPEAG), also based in Zurich. The SEMCAD 3D electromagnetic (EM) simulation software has been used for numerical assessment of EM interference and compatibility (EMI/EMC),[3] antenna design and optimization,[4][5] 5G cellular network research,[6] wireless power transfer (WPT),[7] dosimetry, optics,[8] high-performance computing (HPC), design of microwave[9] and mm-wave waveguide devices, and research on magnetic resonance imaging safety,[10] especially in the context of EM compatibility of implanted medical devices.[11]

All of the functions of SEMCAD, which is no longer on the market, are available as part of the Sim4Life platform, which combines the classical technical computer-aided-design tools of SEMCAD with multi-physics solvers, computational human phantoms, medical-image-based modeling, and physiological tissue models. The Sim4Life platform is used in personalized medicine applications for optimization of treatments involving medical devices and the safety of magnetic resonance imaging. Sim4Life has also been used by medical researchers to study non-invasive methods of brain stimulation[12][13] and transcranial focused ultrasound.

Sim4Life.lite is an online version of Sim4Life that is free-of-charge for students for team-learning and online collaboration with classmates and teachers on limited size projects. Sim4Life.lite and Sim4Life.web rely on open-source o²S²PARC technologies, which were developed as part of the 'Stimulating Peripheral Activity to Relieve Conditions' (SPARC) program of the National Institutes of Health Common Fund to enable collaborative, reproducible, and sustainable computational neurosciences.

References

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  1. ^ "Development of a Multiphysics Simulation Platform for Computational BioMed and Life Sciences (Sim4Life)". ARAMIS. 27 November 2014. Retrieved 17 March 2024.
  2. ^ "R and D project : S4L-CAPITALIS - Extension of the Sim4Life Platform (S4L) for Analysis and Optimization of the Neurovascular and Neurological Devices and Treatments in the Head". ARAMIS. 1 June 2015. Retrieved 17 March 2024.
  3. ^ Aminzadeh, R.; Abdolali, A.; Khaligh, H. (January 2014). "A Numerical Study on the Interaction Between Different Position of Cellular Headsets and a Human Head". The Applied Computational Electromagnetics Society Journal. 29 (1): 91–98 – via River Publishers.
  4. ^ Chang, Chih-Hua; Huang, Shao-Yu; Wei, Wan-Chu; Ma, Pei-Ji (27 August 2014). "Small-size adjustable LTE/WWAN coupled-fed loop antenna for mobile handset applications". Microwave and Optical Technology Letters. 56 (11): 2687–2691. doi:10.1002/mop.28671. S2CID 110896209 – via Wiley Online Library.
  5. ^ Kin-Lu Wong; Chih-Hsien Wu; Wei-Yu Li; Chih-Ming Su; Shih-Huang Yeh; Chia-Lun Tang (23 October 2006). "Simplified hand model for the study of hand-held device antenna". 2006 IEEE Antennas and Propagation Society International Symposium. pp. 2101–2104. doi:10.1109/APS.2006.1710997. ISBN 1-4244-0123-2. S2CID 44054946 – via IEEE Xplore.
  6. ^ Ramachandran, T.; Faruque MRI; Siddiky, A. M.; Islam, M. T. (29 January 2021). "Reduction of 5G cellular network radiation in wireless mobile phone using an asymmetric square shaped passive metamaterial design". Scientific Reports. 11 (1): 2619. Bibcode:2021NatSR..11.2619R. doi:10.1038/s41598-021-82105-7. PMC 7846749. PMID 33514772.
  7. ^ Ho, John S.; Yeh, Alexander J.; Neofytou, Evgenios; Kim, Sanghoek; Tanabe, Yuji; Patlolla, Bhagat; Beygui, Ramin E.; Poon, Ada S. Y. (19 May 2014). "Wireless power transfer to deep-tissue microimplants". Proceedings of the National Academy of Sciences. 111 (22): 7974–7979. Bibcode:2014PNAS..111.7974H. doi:10.1073/pnas.1403002111. PMC 4050616. PMID 24843161.
  8. ^ Л, Головашкин Д.; Л, Казанский Н. (18 December 2010). "Solving diffractive optics problems using graphics processing units". Aerospace and Mechanical Engineering. 9 (4): 159–168 – via VESTNIK of the Samara State Aerospace University.
  9. ^ Kurrant, D.; Bourqui, J.; Fear, E. (19 July 2017). "Surface Estimation for Microwave Imaging". Sensors. 17 (7): 1658. Bibcode:2017Senso..17.1658.. doi:10.3390/s17071658. PMC 5539471. PMID 28753914.
  10. ^ Zheng, Jianfeng; Ji, Xiaohe; Kainz, Wolfgang; Chen, Ji (14 November 2018). "Study on Search Strategies for Assessing the Worst Case RF-Induced Heating for Multi-Configuration Implant System Under MRI". IEEE Transactions on Electromagnetic Compatibility. 62 (1): 43–51. doi:10.1109/TEMC.2018.2879113. S2CID 116607781 – via IEEE Xplore.
  11. ^ Bassen, Howard I.; Angelone, L. M. (1 January 2012). "Evaluation of unintended electrical stimulation from MR gradient fields". Frontiers in Bioscience. 4 (5): 1731–1742. doi:10.2741/e494. PMID 22201989 – via IMR Press.
  12. ^ "Modelling of magnetoelectric nanoparticles for non-invasive brain stimulation: a computational study". Journal of Neural Engineering. 19: 056020. 23 September 2022 – via IOP Publishing.
  13. ^ "Electroporation and cell killing by milli- to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation". Scientific Reports. 12 (1): 1763. 2 February 2022 – via Nature.
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