Portal:Medicine

The Medicine Portal

The color fresco Care of The Sick by Domenico di Bartolo, 1441–1442, depicting the Santa Maria della Scala hospital in Siena, Italy

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.

Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.

Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery. (Full article...)

Featured articles -

Featured articles are displayed here, which represent some of the best content on English Wikipedia.

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  Ray Fletcher Farquharson MBE (4 August 1897 – 1 June 1965) was a Canadian medical doctor, university professor, and medical researcher. Born in Claude, Ontario, he attended and taught at the University of Toronto for most of his life, and was trained and employed at Toronto General Hospital. With co-researcher Arthur Squires, Farquharson was responsible for the discovery of the Farquharson phenomenon, an important principle of endocrinology, which is that administering external hormones suppresses the natural production of that hormone.
  
  He served in the First and Second World Wars, earning appointment as a Member of the Order of the British Empire for his medical work during the latter. He chaired the Penicillin Committee of Canada and served as a medical consultant for the Royal Canadian Air Force. He was awarded the Queen's Coronation Medal in 1953 for his work for the Defence Review Board. Farquharson was also a charter member of the Royal College of Physicians and Surgeons of Canada. (Full article...)
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  Dark Archives: A Librarian's Investigation into the Science and History of Books Bound in Human Skin is a 2020 non-fiction book by the medical librarian and death-positive advocate Megan Rosenbloom. Dealing with anthropodermic bibliopegy, the binding of books in human skin, it expounds upon Rosenbloom's research on such books and their historical, ethical, and cultural implications.
  
  The book focuses on the relationship between anthropodermic bibliopegy and the history of medicine; most confirmed cases of such books were created or owned by medical professionals, in contrast to common stereotypes that they were associated with Nazi Germany, serial killers, or the French Revolution. Rosenbloom discusses how the practice reflects the changing attitudes towards consent, ownership, and disposal of human bodies, and how the history of anthropodermic books intertwines with the history of medical ethics as a field. She interviews librarians, archivists, collectors, and experts on the topic, and examines notable examples of such books and their origins. Though Rosenbloom supports the preservation and maintenance of anthropodermic books, Dark Archives also covers arguments to the contrary, such as those espoused by Princeton University Library senior librarian Paul Needham. (Full article...)
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  A large flap lesion in the femur head typical of late stage Osteochondritis dissecans. In this case, the lesion was caused by avascular necrosis of the bone just under the cartilage.

  
  Osteochondritis dissecans (OCD or OD) is a joint disorder primarily of the subchondral bone in which cracks form in the articular cartilage and the underlying subchondral bone. OCD usually causes pain during and after sports. In later stages of the disorder there will be swelling of the affected joint that catches and locks during movement. Physical examination in the early stages does only show pain as symptom, in later stages there could be an effusion, tenderness, and a crackling sound with joint movement.
  
  
  OCD is caused by blood deprivation of the secondary physes around the bone core of the femoral condyle. This happens to the epiphyseal vessels under the influence of repetitive overloading of the joint during running and jumping sports. During growth such chondronecrotic areas grow into the subchondral bone. There it will show as bone defect area under articular cartilage. The bone will then possibly heal to the surrounding condylar bone in 50% of the cases. Or it will develop into a pseudarthrosis between condylar bone core and osteochondritis flake leaving the articular cartilage it supports prone to damage. The damage is executed by ongoing sport overload. The result is fragmentation (dissection) of both cartilage and bone, and the free movement of these bone and cartilage fragments within the joint space, causing pain, blockage and further damage. OCD has a typical anamnesis with pain during and after sports without any history of trauma. Some symptoms of late stages of osteochondritis dissecans are found with other diseases like rheumatoid disease of children and meniscal ruptures. The disease can be confirmed by X-rays, computed tomography (CT) or magnetic resonance imaging (MRI) scans. (Full article...)
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  Menstrual cycle

  
  The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the uterus (womb) to receive an embryo. These cycles are concurrent and coordinated, normally last between 21 and 35 days, with a median length of 28 days. Menarche (the onset of the first period) usually occurs around the age of 12 years; menstrual cycles continue for about 30–45 years.
  
  Naturally occurring hormones drive the cycles; the cyclical rise and fall of the follicle stimulating hormone prompts the production and growth of oocytes (immature egg cells). The hormone estrogen stimulates the uterus lining (endometrium) to thicken to accommodate an embryo should fertilization occur. The blood supply of the thickened lining provides nutrients to a successfully implanted embryo. If implantation does not occur, the lining breaks down and blood is released. Triggered by falling progesterone levels, menstruation (a "period", in common parlance) is the cyclical shedding of the lining, and is a sign that pregnancy has not occurred. (Full article...)
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  Race Against Time: Searching for Hope in AIDS-Ravaged Africa is a non-fiction book written by Stephen Lewis for the Massey Lectures. Lewis wrote it in early to mid-2005 and House of Anansi Press released it as a corresponding lecture series began in October 2005. Each of the book's chapters were delivered as a different lecture in a different Canadian city, beginning in Vancouver on October 18 and ending in Toronto on October 28. The speeches were aired on CBC Radio One between November 7 and 11. The author and orator, Stephen Lewis, was at that time the United Nations Special Envoy for HIV/AIDS in Africa and former Canadian ambassador to the United Nations. Although he wrote the book and lectures in his role as a concerned Canadian citizen, his criticism of the United Nations (UN), international organizations, and other diplomats, including naming specific people, was called undiplomatic and led several reviewers to speculate whether he would be removed from his UN position.
  
  In the book and the lectures, Lewis argues that significant changes are required to meet the Millennium Development Goals in Africa by their 2015 deadline. Lewis explains the historical context of Africa since the 1980s, citing a succession of disastrous economic policies by international financial institutions that contributed to, rather than reduced, poverty. He connects the structural adjustment loans, with conditions of limited public spending on health and education infrastructure, to the uncontrolled spread of AIDS and subsequent food shortages as the disease infected much of the working-age population. Lewis also addresses such issues as discrimination against women and primary education for children. To help alleviate problems, he ends with potential solutions which mainly require increased funding by G8 countries to levels beyond what they promise. (Full article...)
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  Bupropion, formerly called amfebutamone, and sold under the brand name Wellbutrin among others, is an atypical antidepressant primarily used to treat major depressive disorder, seasonal affective disorder and to support smoking cessation. It is also popular as an add-on medication in the cases of "incomplete response" to the first-line selective serotonin reuptake inhibitor (SSRI) antidepressant. Bupropion has several features that distinguish it from other antidepressants: it does not usually cause sexual dysfunction, it is not associated with weight gain and sleepiness, and it is more effective than SSRIs at improving symptoms of hypersomnia and fatigue. Bupropion, particularly the immediate-release formulation, carries a higher risk of seizure than many other antidepressants, hence caution is recommended in patients with a history of seizure disorder. The medication is taken by mouth.
  
  
  Common adverse effects of bupropion with the greatest difference from placebo are dry mouth, nausea, constipation, insomnia, anxiety, tremor, and excessive sweating. Raised blood pressure is notable. Rare but serious side effects include seizures, liver toxicity, psychosis, and risk of overdose. Bupropion use during pregnancy may be associated with increased likelihood of congenital heart defects. (Full article...)
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  A serpin (white) with its 'reactive centre loop' (blue) bound to a protease (grey). Once the protease attempts catalysis it will be irreversibly inhibited. (PDB: 1K9O​)

  
  Serpins are a superfamily of proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym serpin was originally coined because the first serpins to be identified act on chymotrypsin-like serine proteases (serine protease inhibitors). They are notable for their unusual mechanism of action, in which they irreversibly inhibit their target protease by undergoing a large conformational change to disrupt the target's active site. This contrasts with the more common competitive mechanism for protease inhibitors that bind to and block access to the protease active site.
  
  Protease inhibition by serpins controls an array of biological processes, including coagulation and inflammation, and consequently these proteins are the target of medical research. Their unique conformational change also makes them of interest to the structural biology and protein folding research communities. The conformational-change mechanism confers certain advantages, but it also has drawbacks: serpins are vulnerable to mutations that can result in serpinopathies such as protein misfolding and the formation of inactive long-chain polymers. Serpin polymerisation not only reduces the amount of active inhibitor, but also leads to accumulation of the polymers, causing cell death and organ failure. (Full article...)
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  Young people with polio receiving physiotherapy in the 1950s

  
  The social history of viruses describes the influence of viruses and viral infections on human history. Epidemics caused by viruses began when human behaviour changed during the Neolithic period, around 12,000 years ago, when humans developed more densely populated agricultural communities. This allowed viruses to spread rapidly and subsequently to become endemic. Viruses of plants and livestock also increased, and as humans became dependent on agriculture and farming, diseases such as potyviruses of potatoes and rinderpest of cattle had devastating consequences.
  
  Smallpox and measles viruses are among the oldest that infect humans. Having evolved from viruses that infected other animals, they first appeared in humans in Europe and North Africa thousands of years ago. The viruses were later carried to the New World by Europeans during the time of the Spanish Conquests, but the indigenous people had no natural resistance to the viruses and millions of them died during epidemics. Influenza pandemics have been recorded since 1580, and they have occurred with increasing frequency in subsequent centuries. The pandemic of 1918–19, in which 40–50 million died in less than a year, was one of the most devastating in history. (Full article...)
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  A chest X-ray showing a tumor in the lung (marked by arrow)

  
  Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize, spreading to other parts of the body.
  
  Early lung cancer often has no symptoms and can only be detected by medical imaging. As the cancer progresses, most people experience nonspecific respiratory problems: coughing, shortness of breath, or chest pain. Other symptoms depend on the location and size of the tumor. Those suspected of having lung cancer typically undergo a series of imaging tests to determine the location and extent of any tumors. Definitive diagnosis of lung cancer requires a biopsy of the suspected tumor be examined by a pathologist under a microscope. In addition to recognizing cancerous cells, a pathologist can classify the tumor according to the type of cells it originates from. Around 15% of cases are small-cell lung cancer (SCLC), and the remaining 85% (the non-small-cell lung cancers or NSCLC) are adenocarcinomas, squamous-cell carcinomas, and large-cell carcinomas. After diagnosis, further imaging and biopsies are done to determine the cancer's stage based on how far it has spread. (Full article...)
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  Scanning electron micrograph of Escherichia coli rods

  
  Bacteria (/bækˈtɪəriə/ ^ⓘ; sg.: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit the air, soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria play a vital role in many stages of the nutrient cycle by recycling nutrients and the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in mutualistic, commensal and parasitic relationships with plants and animals. Most bacteria have not been characterised and there are many species that cannot be grown in the laboratory. The study of bacteria is known as bacteriology, a branch of microbiology.
  
  Like all animals, humans carry vast numbers (approximately 10¹³ to 10¹⁴) of bacteria. Most are in the gut, though there are many on the skin. Most of the bacteria in and on the body are harmless or rendered so by the protective effects of the immune system, and many are beneficial, particularly the ones in the gut. However, several species of bacteria are pathogenic and cause infectious diseases, including cholera, syphilis, anthrax, leprosy, tuberculosis, tetanus and bubonic plague. The most common fatal bacterial diseases are respiratory infections. Antibiotics are used to treat bacterial infections and are also used in farming, making antibiotic resistance a growing problem. Bacteria are important in sewage treatment and the breakdown of oil spills, the production of cheese and yogurt through fermentation, the recovery of gold, palladium, copper and other metals in the mining sector (biomining, bioleaching), as well as in biotechnology, and the manufacture of antibiotics and other chemicals. (Full article...)
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  Golding Bird, 1840

  
  Golding Bird FRS FRCP FLS FGS (9 December 1814 – 27 October 1854) was a British medical doctor and a Fellow of the Royal College of Physicians. He became a great authority on kidney diseases and published a comprehensive paper on urinary deposits in 1844. He was also notable for his work in related sciences, especially the medical uses of electricity and electrochemistry. From 1836, he lectured at Guy's Hospital, a well-known teaching hospital in London and now part of King's College London, and published a popular textbook on science for medical students called Elements of Natural Philosophy.
  
  Having developed an interest in chemistry while still a child, largely through self-study, Bird was far enough advanced to deliver lectures to his fellow pupils at school. He later applied this knowledge to medicine and did much research on the chemistry of urine and of kidney stones. In 1842, he was the first to describe oxaluria, a condition which leads to the formation of a particular kind of stone. (Full article...)
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  Micrograph of an intrahepatic cholangiocarcinoma (right of image) adjacent to normal liver cells (left of image). H&E stain.

  
  Cholangiocarcinoma, also known as bile duct cancer, is a type of cancer that forms in the bile ducts. Symptoms of cholangiocarcinoma may include abdominal pain, yellowish skin, weight loss, generalized itching, and fever. Light colored stool or dark urine may also occur. Other biliary tract cancers include gallbladder cancer and cancer of the ampulla of Vater.
  
  
  Risk factors for cholangiocarcinoma include primary sclerosing cholangitis (an inflammatory disease of the bile ducts), ulcerative colitis, cirrhosis, hepatitis C, hepatitis B, infection with certain liver flukes, and some congenital liver malformations. However, most people have no identifiable risk factors. The diagnosis is suspected based on a combination of blood tests, medical imaging, endoscopy, and sometimes surgical exploration. The disease is confirmed by examination of cells from the tumor under a microscope. It is typically an adenocarcinoma (a cancer that forms glands or secretes mucin). (Full article...)
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  Influenza virus

  
  Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease.
  
  There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) is found in cattle and pigs. Influenza A virus and influenza B virus circulate in humans and cause seasonal epidemics, and influenza C virus causes a mild infection, primarily in children. Influenza D virus can infect humans but is not known to cause illness. In humans, influenza viruses are primarily transmitted through respiratory droplets from coughing and sneezing. Transmission through aerosols and surfaces contaminated by the virus also occur. (Full article...)
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  Biopsy of small bowel showing coeliac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts

  
  Coeliac disease (British English) or celiac disease (American English) is a long-term autoimmune disorder, primarily affecting the small intestine, where individuals develop intolerance to gluten, present in foods such as wheat, rye and barley. Classic symptoms include gastrointestinal problems such as chronic diarrhoea, abdominal distention, malabsorption, loss of appetite, and among children failure to grow normally.
  
  Non-classic symptoms are more common, especially in people older than two years. There may be mild or absent gastrointestinal symptoms, a wide number of symptoms involving any part of the body, or no obvious symptoms. Coeliac disease was first described in childhood; however, it may develop at any age. It is associated with other autoimmune diseases, such as Type 1 diabetes mellitus and Hashimoto's thyroiditis, among others. (Full article...)
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  Microscopic image of a Lewy body (adjacent to arrowhead) in a neuron of the substantia nigra; scale bar=20 microns (0.02 mm)

  
  Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and regulation of automatic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive impairment interferes with normal daily functioning. Together with Parkinson's disease dementia, DLB is one of the two Lewy body dementias. It is a common form of dementia, but the prevalence is not known accurately and many diagnoses are missed. The disease was first described on autopsy by Kenji Kosaka in 1976, and he named the condition several years later.
  
  REM sleep behavior disorder (RBD)—in which people lose the muscle paralysis (atonia) that normally occurs during REM sleep and act out their dreams—is a core feature. RBD may appear years or decades before other symptoms. Other core features are visual hallucinations, marked fluctuations in attention or alertness, and parkinsonism (slowness of movement, trouble walking, or rigidity). A presumptive diagnosis can be made if several disease features or biomarkers are present; the diagnostic workup may include blood tests, neuropsychological tests, imaging, and sleep studies. A definitive diagnosis usually requires an autopsy. (Full article...)

Selected image –

This is a dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium.

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  The mouth of a person with symptoms similar to those caused by long-term use of methamphetamine

  
  Meth mouth is a colloquial term used to describe severe tooth decay and tooth loss, as well as tooth fracture, acid erosion, and other oral problems that are often symptomatic to extended use of the drug methamphetamine. The condition is thought to be caused by a combination of side effects of the drug (clenching and grinding of teeth, dry mouth) and lifestyle factors (infrequent oral hygiene, frequent consumption of sugary drinks, as well as neglecting regular dental cleanings and preventive care), which may be present in long-term users. However, the legitimacy of meth mouth as a unique condition has been questioned because of the similar effects of some other drugs on teeth. Images of diseased mouths are often used in anti-drug campaigns.
  
  The condition is difficult to treat, and may involve fillings, fluoride to fight tooth decay and drugs that increase saliva for dry mouth, as well as oral hygiene instruction. It can be dangerous for active methamphetamine users to undergo
  dental surgery because of the cardiac problems that can result from the interaction of local anesthetic with the drug. (Full article...)
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  Andrew Melvin Ramsay (1901–1990) was a British physician, who is known for his research and advocacy on myalgic encephalomyelitis (ME), a chronic disease causing muscle weakness and cognitive dysfunction. Ramsay worked as a consultant at the Royal Free Hospital in London during a mysterious 1955 disease outbreak of what later became known as ME. He studied the disease and similar outbreaks elsewhere. Work by Ramsay showed that although ME seldom caused death, the disease could be highly disabling.
  
  Upset by the lack of sympathy for long-term sufferers, he became their lifelong advocate and co-founded the ME Association. In 1986 he published the first case definition of ME. Two research grants are named after him: the Ramsay research grant from the Solve ME/CFS Initiative and the Ramsay Research Fund of the ME Association. (Full article...)
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  Colored scanning electron microscope (SEM) image of SARS-CoV-2, speculated in 2020 as being the first virus to create Disease X

  
  
  Disease X is a placeholder name that was adopted by the World Health Organization (WHO) in February 2018 on their shortlist of blueprint priority diseases to represent a hypothetical, unknown pathogen that could cause a future epidemic. The WHO adopted the placeholder name to ensure that their planning was sufficiently flexible to adapt to an unknown pathogen (e.g., broader vaccines and manufacturing facilities). Former Director of the US National Institute of Allergy and Infectious Diseases Anthony Fauci stated that the concept of Disease X would encourage WHO projects to focus their research efforts on entire classes of viruses (e.g., flaviviruses), instead of just individual strains (e.g., zika virus), thus improving WHO capability to respond to unforeseen strains.
  
  In 2020, experts, including some of the WHO's own expert advisors, speculated that COVID-19, caused by the SARS-CoV-2 virus strain, met the requirements to be the first Disease X. In December 2024, an unidentified disease in the Democratic Republic of the Congo was sometimes referred to as Disease X, after infecting over 400 people and killing at least 79, later revealed to be an aggressive strain of malaria. (Full article...)
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  MRI of a fractured and dislocated cervical vertebra (C4) in the neck that is compressing the spinal cord

  
  A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function. It is a destructive neurological and pathological state that causes major motor, sensory and autonomic dysfunctions.
  
  Symptoms of spinal cord injury may include loss of muscle function, sensation, or autonomic function in the parts of the body served by the spinal cord below the level of the injury. Injury can occur at any level of the spinal cord and can be complete, with a total loss of sensation and muscle function at lower sacral segments, or incomplete, meaning some nervous signals are able to travel past the injured area of the cord up to the Sacral S4-5 spinal cord segments. Depending on the location and severity of damage, the symptoms vary, from numbness to paralysis, including bowel or bladder incontinence. Long term outcomes also range widely, from full recovery to permanent tetraplegia (also called quadriplegia) or paraplegia. Complications can include muscle atrophy, loss of voluntary motor control, spasticity, pressure sores, infections, and breathing problems. (Full article...)
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  Tawana Vicenia Brawley (born December 15, 1971) is an African American woman from New York who gained notoriety in November 1987 at age 15 when she falsely accused four white men of kidnapping and raping her over a four-day period.
  
  On November 28, 1987, Brawley was found in a trash bag after having been missing for four days from her home in Wappingers Falls, New York. She had racial slurs written on her body and was covered in feces. The feces came from a collie owned by a resident of the building where Brawley was found. Brawley accused four white men of having raped her. The charges received national attention in part because of the appalling condition in which she had been left, her young age, and the professional status of the persons she accused of the crime (including police officers and a prosecuting attorney). Brawley's advisers—Al Sharpton, Alton H. Maddox, and C. Vernon Mason—helped in bringing the case to national prominence. (Full article...)
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  The Society in 1853. Standing: Charles Eliot Ware, Robert William Hooper, Le Baron Russell, and Samuel Parkman. Seated: George Amory Bethune, O. W. Holmes, Samuel Cabot III, Jonathan Mason Warren, William Edward Coale, and James Browne Gregerson.

  
  The Boston Society for Medical Improvement was an elite society of Boston physicians, established in 1828 for "the cultivation of confidence and good feeling between members of the profession; the eliciting and imparting of information upon the different branches of medical science; and the establishment of a Museum and Library of Pathological Anatomy". It held regular meetings until at least 1917. (Full article...)
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  Linderfelt in 1892

  
  Klas August Linderfelt (1847 – March 18, 1900) was an American librarian. A native of Sweden, he emigrated to Milwaukee, Wisconsin and became a teacher and a librarian. As the first librarian of the Milwaukee Public Library, he became a significant figure in the city and in the library profession, becoming the seventh President of the American Library Association. He left both the city and the profession permanently following his arrest for embezzlement. (Full article...)
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  Portrait, c. 1950s–1960s

  
  Johannes Leimena (Often abbreviated as J. Leimana; 6 March 1905 – 29 March 1977), more colloquially referred to as Om Jo, was an Indonesian politician, physician, and national hero. He was one of the longest-serving government ministers in Indonesia, and was the longest-serving under President Sukarno. He filled the roles of Deputy Prime Minister and Minister of Health. An Ambonese Christian, he served in the People's Representative Council and the Constitutional Assembly during the 1950s, and was the chairman of the Indonesian Christian Party from 1951 until 1960.
  
  Leimena was born in Ambon, Maluku, but he grew up in Cimahi and later Batavia (today Jakarta). He became involved in Indonesian nationalist movements through the Ambonese youth group Jong Ambon, and he took part in the two Youth Congresses in 1926 and 1928. In addition, he participated in the Christian ecumenical movement during his time at Batavia's medical school (STOVIA), from which he graduated in 1930. After briefly working in a Batavian hospital, he moved to work at a missionary hospital in Bandung. In 1941, he became a chief physician of hospitals in Purwakarta and Tangerang throughout the Japanese occupation, during which he was briefly arrested and imprisoned. (Full article...)
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  Pituitary apoplexy is bleeding into or impaired blood supply of the pituitary gland. This usually occurs in the presence of a tumor of the pituitary, although in 80% of cases this has not been diagnosed previously. The most common initial symptom is a sudden headache, often associated with a rapidly worsening visual field defect or double vision caused by compression of nerves surrounding the gland. This is often followed by acute symptoms caused by lack of secretion of essential hormones, predominantly adrenal insufficiency.
  
  The diagnosis is achieved with magnetic resonance imaging and blood tests. Treatment is by the timely correction of hormone deficiencies. In many cases, surgical decompression is required. Many people who have had a pituitary apoplexy develop pituitary hormone deficiencies and require long-term hormone supplementation. The first case of the disease was recorded in 1898. (Full article...)
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  Body image disturbance (BID) is a common symptom in patients with eating disorders and is characterized by an altered perception of one's own body.
  
  The onset is mainly attributed to patients with anorexia nervosa who persistently tend to subjectively discern themselves as average or overweight despite adequate, clinical grounds for a classification of being considerably or severely underweight. The symptom is an altered perception of one's body and a severe state of bodily dissatisfaction characterizing the body image disturbance. It is included among the diagnostic criteria for anorexia nervosa in DSM-5 (criterion C). (Full article...)
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  Reconstruction of the trachea and bronchi with x-ray computed tomography showing disruption of the right main bronchus with abnormal lucency (arrow)

  
  Tracheobronchial injury is damage to the tracheobronchial tree (the airway structure involving the trachea and bronchi). It can result from blunt or penetrating trauma to the neck or chest, inhalation of harmful fumes or smoke, or aspiration of liquids or objects.
  
  
  Though rare, TBI is a serious condition; it may cause obstruction of the airway with resulting life-threatening respiratory insufficiency. Other injuries accompany TBI in about half of cases. Of those people with TBI who die, most do so before receiving emergency care, either from airway obstruction, exsanguination, or from injuries to other vital organs. Of those who do reach a hospital, the mortality rate may be as high as 30%. (Full article...)
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  Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.
  
  
  Common side effects include hair loss, bone marrow suppression, vomiting, rash, and inflammation of the mouth. Other serious side effects may include allergic reactions such as anaphylaxis, heart damage, tissue damage at the site of injection, radiation recall, and treatment-related leukemia. People often experience red discoloration of the urine for a few days. Doxorubicin is in the anthracycline and antitumor antibiotic family of medications. It works in part by interfering with the function of DNA. (Full article...)
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  Dorothy P. Rice (June 11, 1922 – February 25, 2017) was an American health statistician whose work contributed to the creation of Medicare in the United States. Rice graduated from the University of Wisconsin–Madison and began working with the US government soon after, but left the workforce to begin raising a child. Just over a decade later, she returned to government work with a position at the Social Security Administration, where she was one of the first scientists to study the economic cost of illness and exposed a lack of health insurance among the elderly.
  
  Rice was later the director of the National Center for Health Statistics from 1976 to 1982, where she helped create the National Death Index. She finished her career at the University of California, San Francisco, where she was a Regents' lecturer and professor emeritus. During her time at the university, she co-authored a paper on the costs of smoking, which impacted ongoing legal negotiations between the US government and the US tobacco industry and contributed to the Tobacco Master Settlement Agreement. (Full article...)
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  Racz in 2010

  
  Gábor Béla Rácz (born 1937), is a Hungarian-American board-certified anesthesiologist and professor emeritus at Texas Tech University Health Science Center (TTUHSC) in Lubbock, Texas, where he is also Chairman Emeritus of the Department of Anesthesiology and Co-Director of Pain Services. He has worked in the field of chronic back pain and complex regional pain syndrome (CRPS).
  
  In 1982, he designed the Racz catheter, a flexible, spring-wound catheter with a small fluoroscopic probe. In 1989, he developed epidural lysis of adhesions, sometimes referred to as percutaneous adhesiolysis, or simply the Racz procedure. It is a minimally invasive, percutaneous intervention for treating chronic spinal pain often due to scarring after post lumbar surgery syndrome, sometimes called failed back surgery, and also low-back and radicular pain from spinal stenosis, a disease of aging. The procedure is somewhat similar to an epidural and is used when conventional methods have failed. The Racz procedure may employ the use of a wire-bound catheter to mechanically break-up or dissolve scar tissue, also called epidural adhesions or fibrosis, which have formed around the nerve roots, and allows for local anesthetics, saline, and steroids to be injected into the affected area. (Full article...)
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  Eilish Cleary (October 22, 1963 – March 22, 2024) was an Irish-born Canadian physician, health officer, and public health advocate who served as the Chief Medical Officer of Health in New Brunswick from 2007 until her termination in 2015, following a controversial decision by the provincial government. Shortly before her dismissal, she was studying glyphosate, a herbicide that is used in the province and has been characterized as potentially being carcinogenic to humans.
  
  Born in Dublin, Cleary became the country's youngest doctor upon graduating from Trinity College. She later moved to Canada where she served as a public health official in Manitoba before moving to New Brunswick to work there. After her termination, Cleary continued worked as a public health official for other provinces until her death in 2024 from ovarian cancer. She received multiple awards and honours throughout her career, including the Queen Elizabeth II Diamond Jubilee Medal as well as appointments to various institutions such as the University of Manitoba and the University of New Brunswick. (Full article...)

Did you know –

• ...the symptoms of Alzheimer's disease as a distinct entity were first identified by Emil Kraepelin, and the characteristic neuropathology was first observed by Alois Alzheimer, a German psychiatrist, in 1906? In this sense, the disease was co-discovered by Kraepelin and Alzheimer, who worked in Kraepelin's laboratory. Because of the overwhelming importance Kraepelin attached to finding the neuropathological basis of psychiatric disorders, Kraepelin made the generous decision that the disease would bear Alzheimer's name.

• ...bariatrics is the branch of medicine that deals with the causes, prevention, and treatment of obesity?
• In 2006, according to the World Health Organization, at least 171 million people worldwide suffer from diabetes?

General images –

The following are images from various Medicine-related articles on Wikipedia.

• 
  AMA Code of Medical Ethics (from Medical ethics)
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  The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care)
• 
  The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine)
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  The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine)
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  Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine)
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  A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine)
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  Charite in Berlin (from History of medicine)
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  An American billing clerk preparing a detailed invoice. (1992) (from Medical billing)
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  Infographic showing how healthcare data flows within the billing process (from Medical billing)
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  Hospital train "Therapist Matvei Mudrov" in Khabarovsk, Russia (from Health care)
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  "Diagram of the causes of mortality in the army in the East" by Florence Nightingale (from History of medicine)
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  Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE) (from History of medicine)
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  A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq.
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  Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine)
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  Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
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  The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance)
• 
  Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine)
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  Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine)
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  A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE) (from History of medicine)
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  A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine)
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  The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine)
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  Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine)
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  "More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics)
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  Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance)
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  Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine)
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  Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report. (from Health care)
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  National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care)
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  A 12th-century Byzantine manuscript of the Hippocratic Oath (from Medical ethics)
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  Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty (from History of medicine)
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  American Civil War hospital at Gettysburg, 1863 (from History of medicine)
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  Medicine during the First World War - medical transport (from History of medicine)
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  Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics (from History of medicine)
• 
  Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine)
• 
  A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine)
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  Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period (from History of medicine)
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  COVID-19 swab testing in Rwanda (2021) (from History of medicine)
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  Traditional medicine in a market in Antananarivo, Madagascar (from Traditional medicine)
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  Health expenditure funding types (from Health insurance)
• 
  Taoist symbol of Yin and Yang (from Medical ethics)
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  Primary care may be provided in community health centers. (from Health care)
• 
  Guy's Hospital in 1820 (from History of medicine)
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  Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine)
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  Replica of Antonie van Leeuwenhoek's microscope of the 1670s (from History of medicine)
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  Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine)
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  Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine)
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  18th-century medical remedies collected by a British Gentry family (from History of medicine)
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  Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care)
• 
  Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine)
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  American combat surgery during the Pacific War, 1943 (from History of medicine)
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  Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care)
• 
  Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care)
• 
  A Ukrainian monument to the HIV pandemic (from History of medicine)
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  Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care)
• 
  healthcare expenditure in Japan by age group (from Health insurance)
• 
  Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine)
• 
  Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics)
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  Galen (129–216 CE), known for his wide insights into anatomy (from History of medicine)
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  Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine)
• 
  Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine)
• 
  Louis Pasteur experimenting on bacteria, c. 1870 (from History of medicine)

More Did you know (auto generated)

• ... that Tang Zonghai was one of the first advocates for the integration of Chinese and Western medicine?
• ... that the Noongar used the Eucalyptus wandoo tree as a medicine and ointment?
• ... that Constance Fozzard was told during her surgical training that women with children could not become consultants?
• ... that Margaret C. Roberts was encouraged to study medicine by LDS Church leader Brigham Young to reduce mortality rates during childbirth?
• ... that fourteenth-century Buddhist monk Tuệ Tĩnh is referred to as a founding father of traditional Vietnamese medicine?
• ... that a lack of screening for pregnant women with syphilis in sub-Saharan Africa is associated with increased infant mortality?

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