OR2H1

OR2H1
Identifiers
Aliases	OR2H1, 6M1-16, HS6M1-16, OLFR42A-9004-14, OR2H6, OR2H8, OR6-2, dJ994E9.4, OLFR42A-9004.14/9026.2, olfactory receptor family 2 subfamily H member 1
External IDs	MGI: 2177474; HomoloGene: 72346; GeneCards: OR2H1; OMA:OR2H1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p22.1 Start 29,457,155 bp End 29,464,328 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 B1 Start 37,401,510 bp End 37,409,170 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle right testis left testis gallbladder caudate nucleus cell monocyte uterine tube hypothalamus blood Top expressed in limb bud More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26716 258470 Ensembl ENSG00000206516 ENSG00000204688 ENSG00000224395 ENSG00000206471 ENSG00000229125 ENSG00000232984 ENSG00000229408 ENSG00000235132 ENSMUSG00000095377 UniProt Q9GZK4 Q7TRL3 RefSeq (mRNA) NM_030883 NM_001318014 NM_001318022 NM_182714 RefSeq (protein) NP_001304943 NP_001304951 NP_112145 NP_874373 Location (UCSC) Chr 6: 29.46 – 29.46 Mb Chr 17: 37.4 – 37.41 Mb PubMed search
Wikidata
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Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi:10.1074/jbc.M212424200. PMID 12637542.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Santos PS, Kellermann T, Uchanska-Ziegler B, et al. (2010). "Genomic architecture of MHC-linked odorant receptor gene repertoires among 16 vertebrate species". Immunogenetics. 62 (9): 569–84. doi:10.1007/s00251-010-0468-6. PMID 20680261. S2CID 23003444.

External links

• OR2H1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.