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Protein-coding gene in the species Homo sapiens
Pacer (also known as Rubicon-like) is a protein that in humans is encoded by the RUBCNL gene .[ 5] autophagy through regulation of PI3KC3 .[ 6]
Pacer contains a Rubicon homology (RH) domain at its C-terminus, which mediates binding to small GTPase Rab7 when Rab7 is phosphorylated following mitochondrial damage.[ 7] [ 5] [ 8] Rubicon and PLEKHM1 .[ 9] autophagy .[ 9]
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