GPR162

GPR162
Identifiers
Aliases	GPR162, A-2, GRCA, G protein-coupled receptor 162
External IDs	MGI: 1315214; HomoloGene: 8400; GeneCards: GPR162; OMA:GPR162 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	6,829,972 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	124,840,946 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; right uterine tube; ; Brodmann area 9; ; amygdala; ; anterior pituitary; ; nucleus accumbens;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; CA3 field; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; cerebellar cortex; ; neural layer of retina; ; central gray substance of midbrain; ; superior colliculus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	27239
	14788
	ENSG00000250510
	ENSMUSG00000038390
	Q16538
	Q3UN16
	NM_019858; NM_014449
	NM_013533; NM_001355257
	NP_055264; NP_062832
	NP_038561; NP_001342186
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 162 is a protein that in humans is encoded by the GPR162 gene.^[5]^[6]

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000250510 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038390 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gloriam DE, Schioth HB, Fredriksson R (Apr 2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim Biophys Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.
^ ^a ^b "Entrez Gene: GPR162 G protein-coupled receptor 162".

Ansari-Lari MA, Muzny DM, Lu J, et al. (1996). "A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13". Genome Res. 6 (4): 314–26. doi:10.1101/gr.6.4.314. PMID 8723724.
Ansari-Lari MA, Shen Y, Muzny DM, et al. (1997). "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination". Genome Res. 7 (3): 268–80. doi:10.1101/gr.7.3.268. PMID 9074930.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000250510 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038390 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15777626-5] Gloriam DE, Schioth HB, Fredriksson R (Apr 2005). "Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship". Biochim Biophys Acta. 1722 (3): 235–46. doi:10.1016/j.bbagen.2004.12.001. PMID 15777626.

[entrez-6] "Entrez Gene: GPR162 G protein-coupled receptor 162".

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References

Further reading