File:Variant Creutzfeldt-Jakob disease (vCJD), typical amyloid plaques, H&E.jpg
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Summary
| Description |
ID#: 10130 Magnified 158X, and stained with H&E (hematoxylin and eosin) staining technique, this light photomicrograph of brain tissue reveals the presence of typical amyloid plaques found in a case of variant Creutzfeldt-Jakob disease (vCJD). Note that the plaques vary in size, and consist of a hyaline eosinophilic core with a peripheral margin of radiating fibrils surrounded by a pale halo. Variant Creutzfeldt-Jakob disease (vCJD) is a prion disease that was first described in 1996 in the United Kingdom. There is now strong scientific evidence that the agent responsible for the outbreak of prion disease in cows, bovine spongiform encephalopathy (BSE or 'mad cow' disease), is the same agent responsible for the outbreak of vCJD in humans. Both disorders are invariably fatal brain diseases with unusually long incubation periods measured in years, and are caused by an unconventional transmissible agent called a prion. vCJD is not the same disease as classic CJD. It has different clinical and pathologic characteristics from classic CJD. Each disease also has a particular genetic profile of the prion protein gene. |
| Date | Creation Date: 2004 |
| Source | Public Health Image Library (PHIL) ID#: 10131 |
| Author |
Content Providers(s): CDC/ Teresa Hammett Photo Credit: Sherif Zaki; MD; PhD; Wun-Ju Shieh; MD; PhD; MPH |
| Permission (Reusing this file) |
Copyright Restrictions: None - This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image. |
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This file is a work of the Centers for Disease Control and Prevention, part of the United States Department of Health and Human Services, taken or made as part of an employee's official duties. As a work of the U.S. federal government, the file is in the public domain.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:59, 30 January 2008 | | 700 × 554 (93 KB) | Patho | {{Information| == Summary == {{Information| |Description=ID#: 10130 Magnified 158X, and stained with H&E (hematoxylin and eosin) staining technique, this light photomicrograph of brain tissue reveals the presence of typical amyloid plaques found in a cas |
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