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English: Tretionin is synthesized from Beta-carotene. The Beta-carotene is firstly cleaved into Beta-carotene 15-15’-monooxygenase through site 1 double bond oxidized to epoxide. The epoxide is attacked by water to form diol in site 1. NADH, as a reduction agent, reduce the alcohol group to aldehydes. Following with aldehyde dehydrogenase 1 family of enzymes (ALD 1), aldehydes are then reduced to tretionin (retinoic acid).
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Biosynthetic pathway of tretinon

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inception

3 June 2019

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current20:14, 3 June 2019Thumbnail for version as of 20:14, 3 June 20199,068 × 13,150 (2.89 MB)EmilyJWUser created page with UploadWizard

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