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Summary
DescriptionSome alternative ways of linking µ chains.jpg
English: A, B) These figures depict two of many possible models of inter-µ chain disulfide bonding in hexameric IgM. As in Figure 1, the Cµ2 disulfide bonds and the Cµ4tp disulfide bonds are represented by a red double arrowhead, and the Cµ3 disulfide bonds are represented by the long double-headed arrows. In both models A and B each type of disulfide bond (Cµ2-Cµ2; Cµ3-Cµ3; Cµ4tp-Cµ4tp) joins µ chains in series with each of the others. Methods for distinguishing these and other models are discussed in reference [28].
C) This representation of pentameric IgM illustrates how J chain might be bonded to µ chains that are not linked via Cµ3 disulfide bonds
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