File:Pegaptanib induced fit binding.png
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Summary
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English: Free aptamer conformation and induced fit binding between the wet AMD treatment Macugen (pegaptanib) and its target, VEGF165, as determined by nuclear magnetic resonance (NMR) spectroscopy. The protein is in yellow. Residues undergoing conformational change on binding are in blue, while the other residues are in orange. Residues participating in binding are highlighted in red.
CC BY 4.0 license. |
| Date | |
| Source | Zhang, N., Chen, Z., Liu, D., Jiang, H., Zhang, Z. K., Lu, A., ... & Zhang, G. (2021). Structural biology for the molecular insight between aptamers and target proteins. International Journal of Molecular Sciences, 22(8), 4093. Publisher: MDPI. |
| Author | Ning Zhang, Zihao Chen, Dingdong Liu, Hewen Jiang, Zong-Kang Zhang, Aiping Lu, Bao-Ting Zhang, Yuanyuan Yu, and Ge Zhang |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 16:49, 1 July 2022 | | 850 × 340 (85 KB) | AllAmericanBreakfast | "a" and "b" subfigure identifiers removed |
| 16:38, 1 July 2022 |  | 850 × 340 (81 KB) | AllAmericanBreakfast | Uploaded a work by Ning Zhang, Zihao Chen, Dingdong Liu, Hewen Jiang, Zong-Kang Zhang, Aiping Lu, Bao-Ting Zhang, Yuanyuan Yu, and Ge Zhang from Zhang, N., Chen, Z., Liu, D., Jiang, H., Zhang, Z. K., Lu, A., ... & Zhang, G. (2021). Structural biology for the molecular insight between aptamers and target proteins. International Journal of Molecular Sciences, 22(8), 4093. Publisher: MDPI. with UploadWizard |
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