File:Official Dapansutrile Mechanism of Action (2).jpg
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Summary
| Description |
English: Figure 3. Dapansutrile's Mechanism of Action. A. Depicts the activation and oligomerization of the NLRP3 inflammsome caused by PAMPS and DAMPS. B. When Dapansutrile is adminstered it binds to the NLRP3 protein and if DAMPS and PAMPS signals are present, Dapansutrile will inhibit NLRP3 inflammasome activation. This leads to an inhibition of the NLRP3 secretion of cytokines (IL-1ẞ and IL-18) and caspase-1 mediated pryopoptosis. Image created in biorender.com. |
| Date | |
| Source | Own work |
| Author | PharmJ 13 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 16:16, 16 December 2020 | | 720 × 504 (157 KB) | PharmJ 13 | Cross-wiki upload from en.wikipedia.org |
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