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English: Overview of histological findings in trichodysplasia spinulosa, a skin condition caused by trichodysplasia spinulosa polyomavirus (TSPyV) found in immunocompromised individuals. Top row (A1-A3) shows healthy control; bottom row (B1-B3) shows TS skin. Low-magnification-power overview (A1, B1); high-power representative examples of epidermis showing thickening of the skin (acanthosis) in TS (A2, B2); high-power representative examples of hair follicles showing enlarged and dysmorphic appearance in TS (A3, B3). Inset in B3 shows characteristic eosinophilic protein granules, probably trichohyalin (arrowheads). H&E stain. Scale bars are 100µm.

Figure 1 from:

Kazem S, van der Meijden E, Wang RC, Rosenberg AS, Pope E, et al. (2014) Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21. PLoS ONE 9(10): e108947. doi: 10.1371/journal.pone.0108947
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Source http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0108947
Author Siamaque Kazem, Els van der Meijden, Richard C. Wang, Arlene S. Rosenberg, Elena Pope, Taylor Benoit, Philip Fleckman, Mariet C. W. Feltkamp
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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current00:14, 13 August 2016Thumbnail for version as of 00:14, 13 August 20163,020 × 1,665 (8.68 MB)Opabinia regalis{{Information |Description ={{en|1=Overview of histological findings in trichodysplasia spinulosa, a skin condition caused by trichodysplasia spinulosa polyomavirus (TSPyV) found in immunocompromised individuals. Top row (A1-A3) shows healthy contro...

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