File:GVHD initiation.jpeg
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Summary
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An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor specific for peptide and MHC molecule recognizes the self-peptide bound to the groove of HLA matched gene as forgein and initiates an immune response. The donor's CD8+ cell targets the recipient’s nucleated cell resulting in graft-versus-host disease.
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I, the copyright holder of this work, hereby publish it under the following license:
  | This work is licensed under the Creative Commons Attribution 4.0 License. |
File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 21:49, 8 February 2017 | | 720 × 540 (47 KB) | Immcarle30 (talk | contribs) | An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient DNA will be translated into protein and is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor spec... |
| 19:18, 8 February 2017 |  | 720 × 540 (45 KB) | Immcarle30 (talk | contribs) | An overview of an immune response during allogeneic stem cell transplantation: A SNP in the coding region of the recipient is polymorphic from the amino acid sequence of a donor's T cell. The T cell receptor specific for peptide and MHC molecule recog... |
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