DescriptionExample of an Application of the Cook-Heilbron Thiazole Synthesis.png
English: An example of an application of the Cook-Heilbron thiazole synthesis. Illustrates the synthesis of 2-methyl-5-aminothiazoles were prepared via condensation and cyclization of aminoacetonitrile and ethyldithioacetate as part of an approach to synthesize pyridyl and thiazoyl bisamide CSF-1R inhibitors for use in novel cancer therapeutics. Adapted from study by 12. Scott et al. (2008). Pyridyl and thiazolyl bisamide CSF-1R inhibitors for the treatment of cancer. Bioorganic & Medicinal Chemistry Letters, 18(17), pp.4794-4797.
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