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English: Comparison of Toll pathways among mammals, Drosophila, and shrimp. In mammals, lipopolysaccharide (LPS) activates the Toll-like receptor (TLR) pathway by directly binding to the TLR4 receptor. In Drosophila, G + bacteria or fungi activate the Toll pathway by functional Spätzle binding to Toll. In shrimp, G + bacteria and G − bacteria all can activate the Toll pathway by their pathogen-associated molecular patterns directly binding to Toll receptors. In shrimp, Toll receptors can directly bind to G + and G − bacteria, whether the Spätzles participated in the Toll pathway (like Drosophila) in shrimp still needs further study.
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Source https://www.researchgate.net/figure/Comparison-of-Toll-pathways-among-mammals-Drosophila-and-shrimp-In-mammals_fig6_319933536
Author J. J. Sun, S. Xu, Z. H. He, X. Z. Shi, X. F. Zhao, J. X. Wang: Activation of Toll Pathway Is Different between Kuruma Shrimp and. In: Frontiers in Immunology. Band 8, 2017, S. 1151, DOI 10.3389/fimmu.2017.01151, PMID 28979261.
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current12:56, 25 December 2018Thumbnail for version as of 12:56, 25 December 2018814 × 581 (127 KB)Brackenheim{{Information |Description={{en|Comparison of Toll pathways among mammals, Drosophila, and shrimp. In mammals, lipopolysaccharide (LPS) activates the Toll-like receptor (TLR) pathway by directly binding to the TLR4 receptor. In Drosophila, G + bacteria or fungi activate the Toll pathway by functional Spätzle binding to Toll. In shrimp, G + bacteria and G − bacteria all can activate the Toll pathway by their pathogen-associated molecular patterns directly binding to Toll receptors. In shrimp,...

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