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English: Cryogenic Optical Localization in Three Dimensions allows to determine the four biotin binding sites in the protein streptavidin.
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Author Weisenburgers

Streptavidin crystal structure: PDB ID: 1STP. Figure was prepared using UCSF Chimera (Pettersen, E.F. et al. J. Comput. Chem. 25, 1605–1612 (2004)).

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