DescriptionAmino Acid Transport & Phagolysosome Resolution.jpg
English: (A) Inside the phagolysosome, hydrolases break down proteins into amino acids, represented by pink and cyan dots. Amino acid transporters, such as LAAT-1 (shown in pink) and SLC-36.1 (shown in cyan), export these different amino acids from the phagolysosome lumen into the cytosol.
(B) The exported amino acids activate mTOR (depicted in green). This activation leads to ARL-8-mediated tubulation. ARL-8 (shown in red) likely interacts with motor proteins and microtubules (represented in orange) to facilitate this process.
(C) The tubulation process results in the formation of phagolysosomal vesicles. This cycle repeats until the phagolysosome is fully resolved.
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Captions
This figure illustrates the process of amino acid transport and phagolysosome resolution in three stages.