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English: The RNA silencing suppressor p19 from the tomato bushy stunt virus, rendered from PDB ID 1R9F. The protein, which forms a functional dimer, is shown colored from blue at the N-terminus to red at the C-terminus; the gray dotted line indicates the dimerization interface. The interaction surface formed from the resulting beta sheet is positively charged and binds double-stranded RNAs of 19 to 21 base pairs. Plants use RNA silencing as a defense mechanism against viruses; the p19 protein serves as a viral counter-defense that specifically binds siRNAs and suppresses the silencing machinery.

Keqiong Ye, Lucy Malinina & Dinshaw J. Patel. Recognition of small interfering RNA by a viral suppressor of RNA silencing. Nature 426, 874-878 (18 December 2003). DOI: 10.1038/nature02213.

http://www.nature.com/nature/journal/v426/n6968/full/nature02213.html
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Author Opabinia regalis
Other versions File:1R9F_tombusvirus_p19.png

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current00:26, 2 December 2016Thumbnail for version as of 00:26, 2 December 20161,200 × 1,200 (520 KB)Opabinia regalis{{Information |Description ={{en|1=The RNA silencing suppressor p19 from the tomato bushy stunt virus, rendered from PDB ID 1R9F. The protein, which forms a functional dimer, is shown colored from blue at the N-terminus to red at the C-terminus; the...
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