Jump to content

Human coronavirus 229E

From Wikipedia, the free encyclopedia
The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.
Alphacoronavirus chicagoense
Transmission electron micrograph of human coronavirus 229E
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Nidovirales
Family: Coronaviridae
Genus: Alphacoronavirus
Subgenus: Duvinacovirus
Species:
Alphacoronavirus chicagoense
Synonyms
  • Human coronavirus 229E
  • HCoV-229E

Alphacoronavirus chicagoense [1]( also called Human coronavirus 229E and abbreviated HCoV-229E) is a species of coronavirus which infects humans and bats.[2] It is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the APN receptor.[3] Along with Human coronavirus OC43 (a member of the Betacoronavirus genus), it is one of the viruses responsible for the common cold.[4][5] HCoV-229E is a member of the genus Alphacoronavirus and subgenus Duvinacovirus.[6][7]

Transmission

HCoV-229E transmits via droplet-respiration and fomites.

Signs and symptoms

HCoV-229E is associated with a range of respiratory symptoms, ranging from the common cold to high-morbidity outcomes such as pneumonia and bronchiolitis. However, such high morbidity outcomes are almost always seen in cases with co-infection with other respiratory pathogens; there is a single published case report to date of a 229E infection that caused acute respiratory distress syndrome (ARDS) in an otherwise healthy patient having no detectable co-infection with another pathogen.[8] HCoV-229E is also among the coronaviruses most frequently codetected with other respiratory viruses, particularly with human respiratory syncytial virus (HRSV).[9][10][11]

Epidemiology

HCoV-229E is one of the seven human coronaviruses which include HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV, SARS-CoV-1, and SARS-CoV-2 and are globally distributed.[12][13] However, the viruses were detected in different parts of the world at different times of the year.[14][15][16] A NCBI-study found a previous HCoV-229E infection in 42.9% – 50.0% of children of 6–12 months of age and in 65% of those 2.5–3.5 years of age.[17]

Virology

HCoV-229E is one of seven known coronaviruses to infect humans. The other six are:[18]

Research

Chloroquine, a zinc ionophore, inhibits the replication of Human coronavirus 229E in cell culture.[19]

Human HCoV-229E, and human HCoV-NL63, likely originated from bats.[20]

History

A researcher at the University of Chicago, Dorothy Hamre, first identified 229E in 1965.[21][22]

In 2021 the International Committee on Taxonomy of Viruses (ICTV) approved a new system of naming viruses, by using binomial names. [23]

In 2023 HCoV-229E was renamed to Alphacoronavirus chicagoense

See also

References

  1. ^ "Taxon Details | ICTV". International Committee on Taxonomy of Viruses (ICTV). Retrieved 25 July 2024.
  2. ^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus–Host Interactions". Diseases. 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. See Table 1.
  3. ^ Fehr AR, Perlman S (2015). "Coronaviruses: An Overview of Their Replication and Pathogenesis". In Maier HJ, Bickerton E, Britton P (eds.). Coronaviruses. Methods in Molecular Biology. Vol. 1282. Springer. pp. 1–23. doi:10.1007/978-1-4939-2438-7_1. ISBN 978-1-4939-2438-7. PMC 4369385. PMID 25720466. See Table 1.
  4. ^ Lau, S. K.; Lee, P.; Tsang, A. K.; Yip, C. C.; Tse, H.; Lee, R. A.; So, L. Y.; Lau, Y. L.; Chan, K. H.; Woo, P. C.; Yuen, K. Y. (2011). "Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination". Journal of Virology. 85 (21): 11325–11337. doi:10.1128/JVI.05512-11. PMC 3194943. PMID 21849456.
  5. ^ Gaunt, E. R.; Hardie, A.; Claas, E. C.; Simmonds, P.; Templeton, K. E. (2010). "Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method". Journal of Clinical Microbiology. 48 (8): 2940–2947. doi:10.1128/JCM.00636-10. PMC 2916580. PMID 20554810.
  6. ^ "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV). October 2018. Retrieved 13 January 2019.
  7. ^ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein.
  8. ^ Vassilara, F.; Spyridaki, A.; Pothitos, G.; Deliveliotou, A.; Papadopoulos, A. (2018). "A Rare Case of Human Coronavirus 229E Associated with Acute Respiratory Distress Syndrome in a Healthy Adult". Case Reports in Infectious Diseases. 2018: 1–4. doi:10.1155/2018/6796839. PMC 5925015. PMID 29850307.
  9. ^ Pene, F.; Merlat, A.; Vabret, A.; Rozenberg, F.; Buzyn, A.; Dreyfus, F.; Cariou, A.; Freymuth, F.; Lebon, P. (2003). "Coronavirus 229E-related pneumonia in immunocompromised patients". Clinical Infectious Diseases. 37 (7): 929–932. doi:10.1086/377612. PMC 7107892. PMID 13130404.
  10. ^ Vabret, A.; Mourez, T.; Gouarin, S.; Petitjean, J.; Freymuth, F. (2003). "An outbreak of coronavirus OC43 respiratory infection in Normandy, France". Clinical Infectious Diseases. 36 (8): 985–989. doi:10.1086/374222. PMC 7109673. PMID 12684910.
  11. ^ Woo, P. C.; Lau, S. K.; Tsoi, H. W.; Huang, Y.; Poon, R. W.; Chu, C. M.; Lee, R. A.; Luk, W. K.; Wong, G. K.; Wong, B. H.; Cheng, V. C.; Tang, B. S.; Wu, A. K.; Yung, R. W.; Chen, H.; Guan, Y.; Chan, K. H.; Yuen, K. Y. (2005). "Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia". The Journal of Infectious Diseases. 192 (11): 1898–2707. doi:10.1086/497151. PMC 7110183. PMID 16267760.
  12. ^ Fields, B. N., D. M. Knipe, and P. M. Howley (ed.). 1996. Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, PA.
  13. ^ Van Der Hoek, L.; Pyrc, K.; Berkhout, B. (2006). "Human coronavirus NL63, a new respiratory virus". FEMS Microbiology Reviews. 30 (5): 760–773. doi:10.1111/j.1574-6976.2006.00032.x. PMC 7109777. PMID 16911043.
  14. ^ Esper, F.; Weibel, C.; Ferguson, D.; Landry, M. L.; Kahn, J. S. (2006). "Coronavirus HKU1 infection in the United States". Emerging Infectious Diseases. 12 (5): 775–779. doi:10.3201/eid1205.051316. PMC 3374449. PMID 16704837.
  15. ^ Gerna, G.; Percivalle, E.; Sarasini, A.; Campanini, G.; Piralla, A.; Rovida, F.; Genini, E.; Marchi, A.; Baldanti, F. (2007). "Human respiratory coronavirus HKU1 versus other coronavirus infections in Italian hospitalised patients". Journal of Clinical Virology. 38 (3): 244–250. doi:10.1016/j.jcv.2006.12.008. PMC 7108341. PMID 17222582.
  16. ^ Kaye, H. S.; Marsh, H. B.; Dowdle, W. R. (1971). "Seroepidemiologic survey of coronavirus (Strain OC 43) related infections in a children's population". American Journal of Epidemiology. 94 (1): 43–49. doi:10.1093/oxfordjournals.aje.a121293. PMC 7109649. PMID 5556222.
  17. ^ Principi, N.; Bosis, S.; Esposito, S. (2010). "Effects of coronavirus infections in children". Emerging Infectious Diseases. 16 (2): 183–188. doi:10.3201/eid1602.090469. PMC 2957994. PMID 20113545.
  18. ^ Leung, Daniel (20 January 2019). "Coronaviruses (including SARS)". Infectious Disease Advisor. Decision Support in Medicine, LLC. Archived from the original on 16 April 2021. Retrieved 1 August 2020.
  19. ^ de Wilde, Adriaan H.; Jochmans, Dirk; Posthuma, Clara C.; Zevenhoven-Dobbe, Jessika C.; van Nieuwkoop, Stefan; Bestebroer, Theo M.; van den Hoogen, Bernadette G.; Neyts, Johan; Snijder, Eric J. (August 2014). "Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture". Antimicrobial Agents and Chemotherapy. 58 (8): 4875–4884. doi:10.1128/AAC.03011-14. PMC 4136071. PMID 24841269.
  20. ^ Tao, Y.; Shi, M.; Chommanard, C.; Queen, K.; Zhang, J.; Markotter, W.; Kuzmin, I. V.; Holmes, E. C.; Tong, S. (2017). "Surveillance of Bat Coronaviruses in Kenya Identifies Relatives of Human Coronaviruses NL63 and 229E and Their Recombination History". Journal of Virology. 91 (5). doi:10.1128/JVI.01953-16. PMC 5309958. PMID 28077633.
  21. ^ Knapp, Alex. "The Secret History Of The First Coronavirus". Forbes. Retrieved 2020-05-06.
  22. ^ Hamre, D.; Procknow, J. J. (1966-01-01). "A New Virus Isolated from the Human Respiratory Tract". Experimental Biology and Medicine. 121 (1): 190–193. doi:10.3181/00379727-121-30734. ISSN 1535-3702. PMID 4285768. S2CID 1314901.
  23. ^ "Binomial nomenclature for virus species (continued)". EPPO Global Database. Retrieved 25 July 2024.
Wikispecies has information related to Human coronavirus 229E.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Human_coronavirus_229E&oldid=1242089030"