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IONICS Mass Spectrometry Group
Company typePrivate
IndustryMedical Devices
Founded2001 in Markham, Ontario Canada[1]
FoundersDr. Reza Javahery, Dr. Lisa Cousins, Dr.Dragan Vukovic, Charles Jolliffe
Headquarters,
Area served
Canada, United States, European Union, Russia,
Key people
Dr. Reza Javahery, President & CEO
ProductsTriple quadrupole mass spectrometers, upgrades
SubsidiariesIONICS MSV Inc.; IONICS MSE Inc.; IONICS MSW Inc. [2]
Websitehttp://www.ionics.ca

IONICS Mass Spectrometry Group is a private, Canadian corporation producing Triple quadrupole mass spectrometers, and upgrade components.[1] It is headquartered in Bolton, Ontario. The company currently offers products and services directly in the Canadian market, through subsidiaries located in the United States and European Union as well as distributors in over ?????? countries. [2]

IONICS produces its mass spectrometers at its Bolton facility, making it the only domestic, Canadian manufacturer of triple quadrupole mass spectrometers.

The company has been recognized for its innovative practices, receiving awards from both government and private sector organizations and holds many patents in regards to triple quadrupole mass spec. technologies. [3] [4]

History

2001: Founded by Dr. Reza Javahery, Dr. Lisa Cousins, Dr. Dragan Vuckovic, and Charles Jolliffe, IONICS Mass Spectrometry Group was initially located in the Toronto suburb of Markham, Ontario. The initial product offering of the company consisted of upgrade components aimed at improving the performance of AB-Sciex's API line of Triple quadrupole mass spectrometers. These upgrades were purchased by major pharmaceutical and research laboratories such as: GlaxoSmithKline, Biovail, Pfizer and Astra Zeneca; as well as several academic and government institutions. [5] [6] [7] [8]

This will be replaced with IONICS headquarters when I figure out how.

2005: Established a subsidiary in the European Union (IONICS MSV Inc.)[1]

2007: Established two American subsidiaries (IONICS MSE and MSW Inc.) which are tasked with providing sales and service to the East and West coasts of the United States, respectively. [1]

200?: As the the company expanded, it moved its corporate headquarters from its original location in Markham, Ontario to a larger facility in the town of Bolton, Ontario.

2009: Introduced the 3Q Molecular Analyzer Triple quadrupole mass spectrometer[9]

Awards

The company has received several awards and grants for its technological developments.

In 2007, IONICS was awarded a National Research Council of Canada (NRC) grant to further develop a new triple quadrupole mass spectrometer (which eventually turned into the 3Q Molecular Analyzer) [10]

In March of 2010, the company won an Innovation and Technology Award from the Research, Innovation and Commercialization Center (RIC Center) for the development of technologies related to the 3Q Molecular Analyzer Triple quadrupole mass spectrometer[4]

In June of 2010, the company received the top prize of $4 million dollars from the Government of Ontario's Ministry of Economic Development and Trade, to further develop and promote its 3Q Molecular Analyzer. [3]

Products

3Q Molecular Analyzer

The 3Q Molecular Analyzer is IONICS product offering in the triple quadrupole mass spectrometry market. It was announced during theAmerican Society for Mass Spectrometry meeting in May of 2009 and the company began to sell the product in the Autumn of 2009. [9]

The technology behind the 3Q Molecular Analyzer was developed by the company itself, and incorporates several patented features including the company's HSID interface upgrade. [11]

The 3Q Molecular Analyzer is unique in terms of layout as it is the only vertically standing triple quad mass spectrometer currently commercially available.

The instrument competes mainly against products such as: the Waters Xevo, Thermo Fisher TSQ and Sciex API lines of mass spectrometers.

File:Ionics3qanalyzer.jpg
IONICS 3Q Molecular Analyzer, Series A

The software used by the 3Q Analyzer, called MolAna was developed for IONICS by Phenomenome Discoveries Inc. (PDI) of Saskatoon, Saskatchewan, Canada.

Upgrades

File:IonicsHSIDdiagram.jpg
IONICS patented HSID interface system

Additionally, IONICS produces upgrades, aimed at improving the performance of several AB-Sciex mass spectrometers such as: the QSTAR, API 3000, API 2000, API 300 and API 365 models.[12]

The company currently offers four types of upgrades:

HSID

The HSID Atmospheric-pressure chemical ionization interface, utilizes heated, laminar flow in order to reduce sample contamination, providing enhanced sensitivity compared to traditional types of interfaces. [12] [13] The HSID can be installed on several older AB/Sciex API mass spectrometers, including the API models 2000, 3000, 4000, and the QSTAR. The HSID system has been purchased by companies such as Pfizer. [8]

Additionally, the company utilizes the HSID system as the interface for its own 3Q Molecular Analyzer triple quadrupole mass spectrometer. [11]

EP10+

The EP10+ is a sensitivity upgrade for API 300 and 365 systems. It has been purchased by organizations such as GlaxoSmithKline. [12]

EPQ+

The EPQ+ is a collision cell upgrade for the API 2000 model of mass spectrometer. It has been utilized by companies such as Astra Zeneca, in their MoIndal, Sweden research facility. [7]

EPXT+

The EPXT+ is a collision cell upgrade that can be installed on a wider variety of mass spectrometers than the EPQ+. It was designed to reduce issues such as crosstalk, and to enable a more efficient fragmentation process. It has been utilized in the past by companies such as Biovail Contract Research in their Toronto, Ontario facility. [6]

Corporate Structure

The company has operations in ??? countries on ??? continents. [1]

From its Bolton, Ontario headquarters, IONICS conducts the majority of its research, development and production of products for the global market. Additionally, sales and service to the Canadian market are provided from this location.[1]

The company has three directly controlled overseas subsidiary corporations, IONICS MSE, MSW, MSV, which serve the Eastern United States, Western United States and Europe respectively. [1]

IONICS MSV

The first subsidiary established by the company was created in 2005, as a joint venture between IONICS Mass Spectrometry Group and Spectrometry Vision BV. From its headquarters in Almere, Holland, IONICS MSV overseas the entirety of IONICS Mass Spectrometry Group's European operations, including offices in the United Kingdom, France and Germany, as well as dedicated distribution and service personnel in several other European countries. [14]

IONICS MSE

Established in 2007, provides sales and product support for customers in the Eastern United States. It is headquartered in Gaithersburg, Maryland. [15]

IONICS MSW

Established in 2007, provides sales and service to customers in the Western United States, from its headquarters in Carlsbad, California.[2]

Distributors

Service is also provided through the company's distributors located in ???? countries.

See Also

IONICS Mass Spectrometry Group Corporate Website

IONICS MSV (Europe) Corporate Webpage

Mass spectrometry

Triple quadrupole mass spectrometer

National Research Council (Canada)

List of mass spectrometry acronyms

Tandem Mass Spectrometry

References

  1. ^ a b c d e f g h "Company". IONICS Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  2. ^ a b c "Contact". IONICS Mass Spectrometry Corporate Website. Retrieved 29 September 2011.
  3. ^ a b "Supporting Advanced Manufacturing In Bolton: McGuinty Government Helps Company Expand, Creates Jobs". Ontario Ministry of Economic Development and Trade. Retrieved 29 September 2011.
  4. ^ a b "Ionics Mass Spectrometry Group wins Innovation & Technology Award" (PDF). IONICS Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  5. ^ "Products: HSID: Field Applications". IONICS MSV Website. Retrieved 29 September 2011.
  6. ^ a b "A New Interface for High Sensitivity High-throughput Samples Analysis: Assessment Using the LC-MS/MS Method for the Quantitative Analysis of Sumatriptan in Human Plasma" (PDF). IONICS Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  7. ^ a b "Astra Zeneca Upgrade Results" (PDF). IONICS Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  8. ^ a b "A Comparison of API3000 Performance Using the Standard Atmospheric Pressure Interface or a Hot Source-Induced Desolvation (HSID) Interface" (PDF). IONICS Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  9. ^ a b "IONICS ANNOUNCES THE PRODUCT RELEASE OF THE IONICS 3Q MOLECULAR ANALYZER AND MolAna ACQUISITION AND QUANTITATION SOFTWARE" (PDF). Ionics Mass Spectrometry Group Corporate Website. Retrieved 29 September 2011.
  10. ^ "Disclosure of Grant and Contribution Awards Over $25,000". National Research Council of Canada Website.
  11. ^ a b "Inventing Value: IONICS 3Q Molecular Analyzer" (PDF). IONICS Corporate Website. Retrieved 29 September 2011.
  12. ^ a b c "IONICS Upgrade Products". IONICS Corporate Website. Retrieved 29 September 2011.
  13. ^ "Enhanced Ion Extraction through Various Pressure Regimes for Improved Sensitivity in LC/MS/MS". IONICS Corporate Website. {{cite web}}: |access-date= requires |url= (help); Missing or empty |url= (help)
  14. ^ "IONICS MSV: Contact Us". IONICS MSV Corporate Website. Retrieved 29 September 2011.
  15. ^ "IONICS MSE: Contact". IONICS MSE Website. Retrieved 29 September 2011.