Bromoacetic acid: Difference between revisions
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| C = 2 | H = 3 | Br = 1 | O = 2 |
| C = 2 | H = 3 | Br = 1 | O = 2 |
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| Appearance = White to light yellow crystalline solid |
| Appearance = White to light yellow crystalline solid |
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| Density = 1.934 g |
| Density = 1.934 g/mL |
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| MeltingPt = 49 - 51 °C |
| MeltingPt = 49 - 51 °C |
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| BoilingPt = 206 - 208 °C |
| BoilingPt = 206 - 208 °C |
Revision as of 18:55, 24 October 2011
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Names | |||
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IUPAC name
2-bromoacetic acid
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Other names
Bromoethanoic acid, α-Bromoacetic acid, Monobromoacetic acid, Carboxymethyl bromide, UN 1938
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Identifiers | |||
3D model (JSmol)
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506167 | |||
ChEMBL | |||
ECHA InfoCard | 100.001.069 | ||
EC Number |
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PubChem CID
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RTECS number |
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CompTox Dashboard (EPA)
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Properties | |||
C2H3BrO2 | |||
Molar mass | 138.948 g·mol−1 | ||
Appearance | White to light yellow crystalline solid | ||
Density | 1.934 g/mL | ||
Melting point | 49 - 51 °C | ||
Boiling point | 206 - 208 °C | ||
polar organic solvents | |||
Acidity (pKa) | 2.86[1] | ||
Refractive index (nD)
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1.4804 (50 °C, D) | ||
Structure | |||
Hexagonal or orthorhombic | |||
Hazards | |||
Occupational safety and health (OHS/OSH): | |||
Main hazards
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Toxic (T), Corrosive {C) | ||
NFPA 704 (fire diamond) | |||
Flash point | 110 °C | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Bromoacetic acid is the chemical compound with the formula CH2BrCO2H. This colorless solid is a relatively strong alkylating agent. Bromoacetic acid and its esters are widely used building blocks in organic synthesis, for example in pharmaceutical chemistry.
The compound is prepared by bromination of acetic acid.[2]
- CH3CO2H + Br2 → CH2BrCO2H + HBr
See also
References
- ^ Dippy, J.F.J., Hughes, S.R.C., Rozanski, A., J. Chem Soc., 1959, 2492.
- ^ Natelson, S.; Gottfried, S. (1955). "Ethyl Bromoacetate". Organic Syntheses
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: CS1 maint: multiple names: authors list (link); Collected Volumes, vol. 3, p. 381.